Chen Fang

Zhe Wang, Yuhua Ru, Fabian Bauer et al.

Magnetic Resonance Imaging (MRI) offers critical insights into microstructural details, however, the spatial resolution of standard 1.5T imaging systems is often limited. In contrast, 7T MRI provides significantly enhanced spatial resolution, enabling finer visualization of anatomical structures. Though this, the high cost and limited availability of 7T MRI hinder its widespread use in clinical settings. To address this challenge, a novel Super-Resolution (SR) model is proposed to generate 7T-like MRI from standard 1.5T MRI scans. Our approach leverages a diffusion-based architecture, incorporating gradient nonlinearity correction and bias field correction data from 7T imaging as guidance. Moreover, to improve deployability, a progressive distillation strategy is introduced. Specifically, the student model refines the 7T SR task with steps, leveraging feature maps from the inference phase of the teacher model as guidance, aiming to allow the student model to achieve progressively 7T SR performance with a smaller, deployable model size. Experimental results demonstrate that our baseline teacher model achieves state-of-the-art SR performance. The student model, while lightweight, sacrifices minimal performance. Furthermore, the student model is capable of accepting MRI inputs at varying resolutions without the need for retraining, significantly further enhancing deployment flexibility. The clinical relevance of our proposed method is validated using clinical data from Massachusetts General Hospital. Our code is available at https://github.com/ZWang78/SR.

Mohammad Sadegh Khorshidi, Navid Yazdanjue, Hassan Gharoun et al.

In machine learning, the exponential growth of data and the associated ``curse of dimensionality'' pose significant challenges, particularly with expansive yet sparse datasets. Addressing these challenges, multi-view ensemble learning (MEL) has emerged as a transformative approach, with feature partitioning (FP) playing a pivotal role in constructing artificial views for MEL. Our study introduces the Semantic-Preserving Feature Partitioning (SPFP) algorithm, a novel method grounded in information theory. The SPFP algorithm effectively partitions datasets into multiple semantically consistent views, enhancing the MEL process. Through extensive experiments on eight real-world datasets, ranging from high-dimensional with limited instances to low-dimensional with high instances, our method demonstrates notable efficacy. It maintains model accuracy while significantly improving uncertainty measures in scenarios where high generalization performance is achievable. Conversely, it retains uncertainty metrics while enhancing accuracy where high generalization accuracy is less attainable. An effect size analysis further reveals that the SPFP algorithm outperforms benchmark models by large effect size and reduces computational demands through effective dimensionality reduction. The substantial effect sizes observed in most experiments underscore the algorithm's significant improvements in model performance.

Sharath Nittur Sridhar, Maciej Szankin, Fang Chen et al.

Recent one-shot Neural Architecture Search algorithms rely on training a hardware-agnostic super-network tailored to a specific task and then extracting efficient sub-networks for different hardware platforms. Popular approaches separate the training of super-networks from the search for sub-networks, often employing predictors to alleviate the computational overhead associated with search. Additionally, certain methods also incorporate the quantization policy within the search space. However, while the quantization policy search for convolutional neural networks is well studied, the extension of these methods to transformers and especially foundation models remains under-explored. In this paper, we demonstrate that by using multi-objective search algorithms paired with lightly trained predictors, we can efficiently search for both the sub-network architecture and the corresponding quantization policy and outperform their respective baselines across different performance objectives such as accuracy, model size, and latency. Specifically, we demonstrate that our approach performs well across both uni-modal (ViT and BERT) and multi-modal (BEiT-3) transformer-based architectures as well as convolutional architectures (ResNet). For certain networks, we demonstrate an improvement of up to $4.80x$ and $3.44x$ for latency and model size respectively, without degradation in accuracy compared to the fully quantized INT8 baselines.

Shuiqiao Yang, Sunny Verma, Borui Cai et al.

Recent works for attributed network clustering utilize graph convolution to obtain node embeddings and simultaneously perform clustering assignments on the embedding space. It is effective since graph convolution combines the structural and attributive information for node embedding learning. However, a major limitation of such works is that the graph convolution only incorporates the attribute information from the local neighborhood of nodes but fails to exploit the mutual affinities between nodes and attributes. In this regard, we propose a variational co-embedding learning model for attributed network clustering (VCLANC). VCLANC is composed of dual variational auto-encoders to simultaneously embed nodes and attributes. Relying on this, the mutual affinity information between nodes and attributes could be reconstructed from the embedding space and served as extra self-supervised knowledge for representation learning. At the same time, trainable Gaussian mixture model is used as priors to infer the node clustering assignments. To strengthen the performance of the inferred clusters, we use a mutual distance loss on the centers of the Gaussian priors and a clustering assignment hardening loss on the node embeddings. Experimental results on four real-world attributed network datasets demonstrate the effectiveness of the proposed VCLANC for attributed network clustering.

Chen Fang, Panuwat Janwattanapong, Chunfei Li et al.

Multiple modalities of biomarkers have been proved to be very sensitive in assessing the progression of Alzheimer's disease (AD), and using these modalities and machine learning algorithms, several approaches have been proposed to assist in the early diagnosis of AD. Among the recent investigated state-of-the-art approaches, Gaussian discriminant analysis (GDA)-based approaches have been demonstrated to be more effective and accurate in the classification of AD, especially for delineating its prodromal stage of mild cognitive impairment (MCI). Moreover, among those binary classification investigations, the local feature extraction methods were mostly used, which made them hardly be applied to a practical computer aided diagnosis system. Therefore, this study presents a novel global feature extraction model taking advantage of the recent proposed GDA-based dual high-dimensional decision spaces, which can significantly improve the early diagnosis performance comparing to those local feature extraction methods. In the true test using 20% held-out data, for discriminating the most challenging MCI group from the cognitively normal control (CN) group, an F1 score of 91.06%, an accuracy of 88.78%, a sensitivity of 91.80%, and a specificity of 83.78% were achieved that can be considered as the best performance obtained so far.

Daniel N. Rockmore, Chen Fang, Nicholas J. Foti et al.

We explore how ideas from infectious disease and genetics can be used to uncover patterns of cultural inheritance and innovation in a corpus of 591 national constitutions spanning 1789 - 2008. Legal "Ideas" are encoded as "topics" - words statistically linked in documents - derived from topic modeling the corpus of constitutions. Using these topics we derive a diffusion network for borrowing from ancestral constitutions back to the US Constitution of 1789 and reveal that constitutions are complex cultural recombinants. We find systematic variation in patterns of borrowing from ancestral texts and "biological"-like behavior in patterns of inheritance with the distribution of "offspring" arising through a bounded preferential-attachment process. This process leads to a small number of highly innovative (influential) constitutions some of which have yet to have been identified as so in the current literature. Our findings thus shed new light on the critical nodes of the constitution-making network. The constitutional network structure reflects periods of intense constitution creation, and systematic patterns of variation in constitutional life-span and temporal influence.