Suqing Tian

Jiashu Dong, Jiabing Xiang, Lisheng Geng et al.

X-ray computed tomography (CT) is widely used in medical imaging, with sparse-view reconstruction offering an effective way to reduce radiation dose. However, ill-posed conditions often result in severe streak artifacts. Recent advances in deep learning-based methods have improved reconstruction quality, but challenges still remain. To address these challenges, we propose a novel semantic feature contrastive learning loss function that evaluates semantic similarity in high-level latent spaces and anatomical similarity in shallow latent spaces. Our approach utilizes a three-stage U-Net-based architecture: one for coarse reconstruction, one for detail refinement, and one for semantic similarity measurement. Tests on a chest dataset with orthogonal projections demonstrate that our method achieves superior reconstruction quality and faster processing compared to other algorithms. The results show significant improvements in image quality while maintaining low computational complexity, making it a practical solution for orthogonal CT reconstruction.

Dongdong Meng, Sheng Li, Hao Wu et al.

Accurate automatic medical image segmentation relies on high-quality, dense annotations, which are costly and time-consuming. Weakly supervised learning provides a more efficient alternative by leveraging sparse and coarse annotations instead of dense, precise ones. However, segmentation performance degradation and overfitting caused by sparse annotations remain key challenges. To address these issues, we propose CmFNet, a novel 3D weakly supervised cross-modal medical image segmentation approach. CmFNet consists of three main components: a modality-specific feature learning network, a cross-modal feature learning network, and a hybrid-supervised learning strategy. Specifically, the modality-specific feature learning network and the cross-modal feature learning network effectively integrate complementary information from multi-modal images, enhancing shared features across modalities to improve segmentation performance. Additionally, the hybrid-supervised learning strategy guides segmentation through scribble supervision, intra-modal regularization, and inter-modal consistency, modeling spatial and contextual relationships while promoting feature alignment. Our approach effectively mitigates overfitting, delivering robust segmentation results. It excels in segmenting both challenging small tumor regions and common anatomical structures. Extensive experiments on a clinical cross-modal nasopharyngeal carcinoma (NPC) dataset (including CT and MR imaging) and the publicly available CT Whole Abdominal Organ dataset (WORD) show that our approach outperforms state-of-the-art weakly supervised methods. In addition, our approach also outperforms fully supervised methods when full annotation is used. Our approach can facilitate clinical therapy and benefit various specialists, including physicists, radiologists, pathologists, and oncologists.