Lakshmi Raman

Fateme Golivand, Michael Skinner, Saurabh Mathur et al.

Pediatric critical care is a dynamic, high-stakes process involving constant monitoring and adjustments in life-saving treatments. Modeling these interventions is crucial for effective decision support. To address the challenges of high complexity and data scarcity in pediatric Extracorporeal Membrane Oxygenation (ECMO), we frame clinical decision-making as learning to act from trajectories, i.e., imitation learning that learns action models from observational data, with a key feature that actions are not directly observed. We consider TabPFN, a recent transformer-based approach for tabular data, and traditional baselines including XGBoost and Multi-Layer Perceptrons(MLPs) on real-world pediatric ECMO data to learn the action models. We find that the TabPFN-based approach consistently outperforms these classical baselines, supporting its use as a strong clinician-behavior baseline for pediatric ECMO decision support.

Michael A. Skinner, Lakshmi Raman, Neel Shah et al.

The increased use of electronic health records has made possible the automated extraction of medical policies from patient records to aid in the development of clinical decision support systems. We adapted a boosted Statistical Relational Learning (SRL) framework to learn probabilistic rules from clinical hospital records for the management of physiologic parameters of children with severe cardiac or respiratory failure who were managed with extracorporeal membrane oxygenation. In this preliminary study, the results were promising. In particular, the algorithm returned logic rules for medical actions that are consistent with medical reasoning.