Sara Khalid

Anshu Ankolekar, Sebastian Boie, Maryam Abdollahyan et al.

Federated Learning (FL) has emerged as a promising solution to address the limitations of centralised machine learning (ML) in oncology, particularly in overcoming privacy concerns and harnessing the power of diverse, multi-center data. This systematic review synthesises current knowledge on the state-of-the-art FL in oncology, focusing on breast, lung, and prostate cancer. Distinct from previous surveys, our comprehensive review critically evaluates the real-world implementation and impact of FL on cancer care, demonstrating its effectiveness in enhancing ML generalisability, performance and data privacy in clinical settings and data. We evaluated state-of-the-art advances in FL, demonstrating its growing adoption amid tightening data privacy regulations. FL outperformed centralised ML in 15 out of the 25 studies reviewed, spanning diverse ML models and clinical applications, and facilitating integration of multi-modal information for precision medicine. Despite the current challenges identified in reproducibility, standardisation and methodology across studies, the demonstrable benefits of FL in harnessing real-world data and addressing clinical needs highlight its significant potential for advancing cancer research. We propose that future research should focus on addressing these limitations and investigating further advanced FL methods, to fully harness data diversity and realise the transformative power of cutting-edge FL in cancer care.

Usman Nazir, Wadood Islam, Sara Khalid et al.

Land-use monitoring is fundamental for spatial planning, particularly in view of compound impacts of growing global populations and climate change. Despite existing applications of deep learning in land use monitoring, standard convolutional kernels in deep neural networks limit the applications of these networks to the Euclidean domain only. Considering the geodesic nature of the measurement of the earth's surface, remote sensing is one such area that can benefit from non-Euclidean and spherical domains. For this purpose, we designed a novel Graph Neural Network architecture for spatial and spatio-temporal classification using satellite imagery to acquire insights into socio-economic indicators. We propose a hybrid attention method to learn the relative importance of irregular neighbors in remote sensing data. Instead of classifying each pixel, we propose a method based on Simple Linear Iterative Clustering (SLIC) image segmentation and Graph Attention Network. The superpixels obtained from SLIC become the nodes of our Graph Convolution Network (GCN). A region adjacency graph (RAG) is then constructed where each superpixel is connected to every other adjacent superpixel in the image, enabling information to propagate globally. Finally, we propose a Spatially driven Attention Graph Neural Network (SAG-NN) to classify each RAG. We also propose an extension to our SAG-NN for spatio-temporal data. Unlike regular grids of pixels in images, superpixels are irregular in nature and cannot be used to create spatio-temporal graphs. We introduce temporal bias by combining unconnected RAGs from each image into one supergraph. This is achieved by introducing block adjacency matrices resulting in novel Spatio-Temporal driven Attention Graph Neural Network with Block Adjacency matrix (STAG-NN-BA). SAG-NN and STAG-NN-BA outperform graph and non-graph baselines on Asia14 and C2D2 datasets efficiently.

Usman Nazir, Murtaza Taj, Momin Uppal et al.

Industrial air pollution has a direct health impact and is a major contributor to climate change. Small scale industries particularly bull-trench brick kilns are one of the key sources of air pollution in South Asia often creating hazardous levels of smog that is injurious to human health. To mitigate the climate and health impact of the kiln industry, fine-grained kiln localization at different geographic locations is needed. Kiln localization using multi-spectral remote sensing data such as vegetation indices can result in a noisy estimates whereas relying solely on high-resolution imagery is infeasible due to cost and compute complexities. This paper proposes a fusion of spatio-temporal multi-spectral data with high-resolution imagery for detection of brick kilns within the "Brick-Kiln-Belt" of South Asia. We first perform classification using low-resolution spatio-temporal multi-spectral data from Sentinel-2 imagery by combining vegetation, burn, build up and moisture indices. Next, orientation aware object detector YOLOv3 (with theta value) is implemented for removal of false detections and fine-grained localization. Our proposed technique, when compared with other benchmarks, results in a 21 times improvement in speed with comparable or higher accuracy when tested over multiple countries.

Usman Nazir, Xidong Chen, Hafiz Muhammad Abubakar et al.

Brick kilns are a major source of air pollution and forced labor in South Asia, yet large-scale monitoring remains limited by sparse and outdated ground data. We study brick kiln detection at scale using high-resolution satellite imagery and curate a multi city zoom-20 (0.149 meters per pixel) resolution dataset comprising over 1.3 million image tiles across five regions in South and Central Asia. We propose ClimateGraph, a region-adaptive graph-based model that captures spatial and directional structure in kiln layouts, and evaluate it against established graph learning baselines. In parallel, we assess a remote sensing based detection pipeline and benchmark it against recent foundation models for satellite imagery. Our results highlight complementary strengths across graph, foundation, and remote sensing approaches, providing practical guidance for scalable brick kiln monitoring from satellite imagery.

Usman Nazir, Disha Gomathinayagam, Muhammad Kamran et al.

Pakistan experienced an unusually severe flood season between June and December 2025, with cascading impacts on population, infrastructure, and agriculture. Existing operational flood products (e.g., UNOSAT) provide valuable episode-level snapshots but rarely deliver spatially and temporally continuous inundation maps at near-real-time latency within the country. We present a multi-sensor, ensemble-based remote-sensing framework for continuous flood nowcasting in Pakistan that integrates Sentinel-1 SAR, Harmonized Landsat-Sentinel (HLS L30 and S30), MODIS, and VIIRS observations on a harmonized grid in Google Earth Engine. The framework employs a tiered nowcasting ensemble that prioritizes higher-resolution sensors (Sentinel-1 and HLS) and falls back to MODIS and VIIRS when necessary, preserving daily continuity of flood extent at each sensor's native resolution. Applied to the 2025 monsoon period, the system generates near-real-time, spatially consistent inundation maps across Pakistan. As a nowcasting case study, we track the super-flood of 26 August-7 September 2025 day by day, demonstrating the framework's ability to capture the evolving flood footprint in near real time and extend beyond the temporal limits of episodic mapping products. Validation against GloFAS discharge anomalies and precipitation datasets (CHIRPS v3.0, MSWEP) shows strong agreement with observed hydrometeorological conditions. By integrating nowcast outputs with exposure layers (WorldPop, ESA WorldCover, Giga-HOTOSM), the framework enables rapid estimation of affected populations, cropland, and critical infrastructure, supporting timely disaster response and resilience planning in South Asia.

Usman Nazir, I-Han Cheng, Sara Khalid

Malaria, childhood acute respiratory infection, and child undernutrition together account for over two million deaths annually in children under five, with the burden concentrated in low and middle-income countries where climate variability modulates transmission, exposure, and nutritional outcomes. Routine health surveillance in these settings remains sparse and reactive. Satellite-derived representations of the Earth's surface offer a scalable, low-cost complement to traditional covariates, yet their utility as predictors of population health outcomes is poorly characterised. We summarise findings from three studies evaluating AlphaEarth Foundations 64-dimensional satellite embeddings as predictors of population health outcomes, focusing on vulnerable populations. The studies span infectious disease (malaria, respiratory infection) and stunting. In each study, embeddings provide predictive value at sufficient spatial granularity: (i) malaria prediction across Nigeria shows consistent per-region R^2 gains; (ii) childhood acute respiratory infection prediction across 11 DHS countries increases pooled R^2 from 0.157 to 0.206 across three tree-based estimators; (iii) stunting prediction across 35 countries is neutral at country level due to collinearity with fixed effects. The stunting case is currently limited by lack of DHS cluster-level coordinates, which is the next key experiment.

João Matos, Ben Van Calster, Leo Anthony Celi et al.

Predictive artificial intelligence (AI) offers an opportunity to improve clinical practice and patient outcomes, but risks perpetuating biases if fairness is inadequately addressed. However, the definition of "fairness" remains unclear. We conducted a scoping review to identify and critically appraise fairness metrics for clinical predictive AI. We defined a "fairness metric" as a measure quantifying whether a model discriminates (societally) against individuals or groups defined by sensitive attributes. We searched five databases (2014-2024), screening 820 records, to include 41 studies, and extracted 62 fairness metrics. Metrics were classified by performance-dependency, model output level, and base performance metric, revealing a fragmented landscape with limited clinical validation and overreliance on threshold-dependent measures. Eighteen metrics were explicitly developed for healthcare, including only one clinical utility metric. Our findings highlight conceptual challenges in defining and quantifying fairness and identify gaps in uncertainty quantification, intersectionality, and real-world applicability. Future work should prioritise clinically meaningful metrics.