James E. Baciak

Yuheng Li, Yuan Gao, Haoyu Dong et al.

Computed tomography (CT) is a central to three-dimensional medical imaging, yet CT-based artificial intelligence remains fragmented across task-specific models for segmentation, classification, registration, and report analysis. Here we present FlexiCT, a family of CT foundation models trained by agglomerative continual pretraining on 266,227 CT volumes from 56 publicly available datasets, forming a large-scale public resource for CT representation learning. FlexiCT uses agglomerative pretraining across three stages: two-dimensional axial pretraining, three-dimensional anatomical pretraining and report-guided semantic alignment. This training strategy supports slice-level, volume-level and vision-language analysis. Across five downstream task families (segmentation, classification, registration, vision-language understanding and clinical retrieval), FlexiCT matches or exceeds prior task-specific approaches on multiple benchmarks. Its embeddings further organize CT scans along gradients associated with various tumor stages, suggesting that CT foundation models can capture imaging features relevant to disease phenotype characterization. Code is available at https://github.com/ricklisz/FlexiCT

Jose F. Ruiz-Munoz, Jyothier K. Nimmagadda, Tyler G. Dowd et al.

High-resolution cameras have become very helpful for plant phenotyping by providing a mechanism for tasks such as target versus background discrimination, and the measurement and analysis of fine-above-ground plant attributes. However, the acquisition of high-resolution (HR) imagery of plant roots is more challenging than above-ground data collection. Thus, an effective super-resolution (SR) algorithm is desired for overcoming resolution limitations of sensors, reducing storage space requirements, and boosting the performance of later analysis, such as automatic segmentation. We propose a SR framework for enhancing images of plant roots by using convolutional neural networks (CNNs). We compare three alternatives for training the SR model: i) training with non-plant-root images, ii) training with plant-root images, and iii) pretraining the model with non-plant-root images and fine-tuning with plant-root images. We demonstrate on a collection of publicly available datasets that the SR models outperform the basic bicubic interpolation even when trained with non-root datasets. Also, our segmentation experiments show that high performance on this task can be achieved independently of the SNR. Therefore, we conclude that the quality of the image enhancement depends on the application.