Zewen Qiang

Haochun Wang, Chi Liu, Nuwa Xi et al.

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks due to the need for medical expertise in the responses. In response to this challenge, we propose HuaTuo, a LLaMA-based model that has been supervised-fine-tuned with generated QA (Question-Answer) instances. The experimental results demonstrate that HuaTuo generates responses that possess more reliable medical knowledge. Our proposed HuaTuo model is accessible at https://github.com/SCIR-HI/Huatuo-Llama-Med-Chinese.

Haochun Wang, Sendong Zhao, Zewen Qiang et al.

Large Language Models (LLMs) have demonstrated remarkable success in diverse natural language processing (NLP) tasks in general domains. However, LLMs sometimes generate responses with the hallucination about medical facts due to limited domain knowledge. Such shortcomings pose potential risks in the utilization of LLMs within medical contexts. To address this challenge, we propose knowledge-tuning, which leverages structured medical knowledge bases for the LLMs to grasp domain knowledge efficiently and facilitate reliable response generation. We also release cMedKnowQA, a Chinese medical knowledge question-answering dataset constructed from medical knowledge bases to assess the medical knowledge proficiency of LLMs. Experimental results show that the LLMs which are knowledge-tuned with cMedKnowQA, can exhibit higher levels of accuracy in response generation compared with vanilla instruction-tuning and offer a new reliable way for the domain adaptation of LLMs.

Yanrui Du, Sendong Zhao, Haochun Wang et al.

Explaining black-box model behavior with natural language has achieved impressive results in various NLP tasks. Recent research has explored the utilization of subsequences from the input text as a rationale, providing users with evidence to support the model decision. Although existing frameworks excel in generating high-quality rationales while achieving high task performance, they neglect to account for the unreliable link between the generated rationale and model decision. In simpler terms, a model may make correct decisions while attributing wrong rationales, or make poor decisions while attributing correct rationales. To mitigate this issue, we propose a unified two-stage framework known as Self-Attribution and Decision-Making (SADM). Through extensive experiments on five reasoning datasets from the ERASER benchmark, we demonstrate that our framework not only establishes a more reliable link between the generated rationale and model decision but also achieves competitive results in task performance and the quality of rationale. Furthermore, we explore the potential of our framework in semi-supervised scenarios.

Haochun Wang, Sendong Zhao, Jingbo Wang et al.

Multi-agent collaboration has emerged as a pivotal paradigm for addressing complex, distributed tasks in large language model (LLM)-driven applications. While prior research has focused on high-level architectural frameworks, the granular mechanisms governing agents, critical to performance and scalability, remain underexplored. This study systematically investigates four dimensions of collaboration strategies: (1) agent governance, (2) participation control, (3) interaction dynamics, and (4) dialogue history management. Through rigorous experimentation under two context-dependent scenarios: Distributed Evidence Integration (DEI) and Structured Evidence Synthesis (SES), we quantify the impact of these strategies on both task accuracy and computational efficiency. Our findings reveal that centralized governance, instructor-led participation, ordered interaction patterns, and instructor-curated context summarization collectively optimize the trade-off between decision quality and resource utilization with the support of the proposed Token-Accuracy Ratio (TAR). This work establishes a foundation for designing adaptive, scalable multi-agent systems, shifting the focus from structural novelty to strategic interaction mechanics.

Muzhen Cai, Sendong Zhao, Haochun Wang et al.

Artificial Intelligence predicts drug properties by encoding drug molecules, aiding in the rapid screening of candidates. Different molecular representations, such as SMILES and molecule graphs, contain complementary information for molecular encoding. Thus exploiting complementary information from different molecular representations is one of the research priorities in molecular encoding. Most existing methods for combining molecular multi-modalities only use molecular-level information, making it hard to encode intra-molecular alignment information between different modalities. To address this issue, we propose a multi-granularity fusion method that is MolFusion. The proposed MolFusion consists of two key components: (1) MolSim, a molecular-level encoding component that achieves molecular-level alignment between different molecular representations. and (2) AtomAlign, an atomic-level encoding component that achieves atomic-level alignment between different molecular representations. Experimental results show that MolFusion effectively utilizes complementary multimodal information, leading to significant improvements in performance across various classification and regression tasks.