Meixu Chen

Yunxiang Li, Meixu Chen, Kai Wang et al.

Image translation has wide applications, such as style transfer and modality conversion, usually aiming to generate images having both high degrees of realism and faithfulness. These problems remain difficult, especially when it is important to preserve content structures. Traditional image-level similarity metrics are of limited use, since the content structures of an image are high-level, and not strongly governed by pixel-wise faithfulness to an original image. To fill this gap, we introduce SAMScore, a generic content structural similarity metric for evaluating the faithfulness of image translation models. SAMScore is based on the recent high-performance Segment Anything Model (SAM), which allows content similarity comparisons with standout accuracy. We applied SAMScore on 19 image translation tasks, and found that it is able to outperform all other competitive metrics on all tasks. We envision that SAMScore will prove to be a valuable tool that will help to drive the vibrant field of image translation, by allowing for more precise evaluations of new and evolving translation models. The code is available at https://github.com/Kent0n-Li/SAMScore.

Meixu Chen, Kai Wang, Payal Kapur et al.

Purpose: A reliable cancer prognosis model for clear cell renal cell carcinoma (ccRCC) can enhance personalized treatment. We developed a multi-modal ensemble model (MMEM) that integrates pretreatment clinical data, multi-omics data, and histopathology whole slide image (WSI) data to predict overall survival (OS) and disease-free survival (DFS) for ccRCC patients. Methods: We analyzed 226 patients from The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma (TCGA-KIRC) dataset, which includes OS, DFS follow-up data, and five data modalities: clinical data, WSIs, and three multi-omics datasets (mRNA, miRNA, and DNA methylation). Separate survival models were built for OS and DFS. Cox-proportional hazards (CPH) model with forward feature selection is used for clinical and multi-omics data. Features from WSIs were extracted using ResNet and three general-purpose foundation models. A deep learning-based CPH model predicted survival using encoded WSI features. Risk scores from all models were combined based on training performance. Results: Performance was assessed using concordance index (C-index) and AUROC. The clinical feature-based CPH model received the highest weight for both OS and DFS tasks. Among WSI-based models, the general-purpose foundation model (UNI) achieved the best performance. The final MMEM model surpassed single-modality models, achieving C-indices of 0.820 (OS) and 0.833 (DFS), and AUROC values of 0.831 (3-year patient death) and 0.862 (cancer recurrence). Using predicted risk medians to stratify high- and low-risk groups, log-rank tests showed improved performance in both OS and DFS compared to single-modality models. Conclusion: MMEM is the first multi-modal model for ccRCC patients, integrating five data modalities. It outperformed single-modality models in prognostic ability and has the potential to assist in ccRCC patient management if independently validated.

Yaoyao Qian, Yuanli Wang, Jinda Zhang et al.

Current evaluation of web agents largely reduces to binary success metrics or conformity to a single reference trajectory, ignoring the structural diversity present in benchmark datasets. We present WebGraphEval, a framework that abstracts trajectories from multiple agents into a unified, weighted action graph. This representation is directly compatible with benchmarks such as WebArena, leveraging leaderboard runs and newly collected trajectories without modifying environments. The framework canonically encodes actions, merges recurring behaviors, and applies structural analyses including reward propagation and success-weighted edge statistics. Evaluations across thousands of trajectories from six web agents show that the graph abstraction captures cross-model regularities, highlights redundancy and inefficiency, and identifies critical decision points overlooked by outcome-based metrics. By framing web interaction as graph-structured data, WebGraphEval establishes a general methodology for multi-path, cross-agent, and efficiency-aware evaluation of web agents.

Meixu Chen, Richard Webb, Alan C. Bovik

The requirements of much larger file sizes, different storage formats, and immersive viewing conditions of VR pose significant challenges to the goals of acquiring, transmitting, compressing, and displaying high-quality VR content. At the same time, the great potential of deep learning to advance progress on the video compression problem has driven a significant research effort. Because of the high bandwidth requirements of VR, there has also been significant interest in the use of space-variant, foveated compression protocols. We have integrated these techniques to create an end-to-end deep learning video compression framework. A feature of our new compression model is that it dispenses with the need for expensive search-based motion prediction computations. This is accomplished by exploiting statistical regularities inherent in video motion expressed by displaced frame differences. Foveation protocols are desirable since only a small portion of a video viewed in VR may be visible as a user gazes in any given direction. Moreover, even within a current field of view (FOV), the resolution of retinal neurons rapidly decreases with distance (eccentricity) from the projected point of gaze. In our learning based approach, we implement foveation by introducing a Foveation Generator Unit (FGU) that generates foveation masks which direct the allocation of bits, significantly increasing compression efficiency while making it possible to retain an impression of little to no additional visual loss given an appropriate viewing geometry. Our experiment results reveal that our new compression model, which we call the Foveated MOtionless VIdeo Codec (Foveated MOVI-Codec), is able to efficiently compress videos without computing motion, while outperforming foveated version of both H.264 and H.265 on the widely used UVG dataset and on the HEVC Standard Class B Test Sequences.