Nicolas Guigui

Nina Miolane, Alice Le Brigant, Johan Mathe et al.

We introduce Geomstats, an open-source Python toolbox for computations and statistics on nonlinear manifolds, such as hyperbolic spaces, spaces of symmetric positive definite matrices, Lie groups of transformations, and many more. We provide object-oriented and extensively unit-tested implementations. Among others, manifolds come equipped with families of Riemannian metrics, with associated exponential and logarithmic maps, geodesics and parallel transport. Statistics and learning algorithms provide methods for estimation, clustering and dimension reduction on manifolds. All associated operations are vectorized for batch computation and provide support for different execution backends, namely NumPy, PyTorch and TensorFlow, enabling GPU acceleration. This paper presents the package, compares it with related libraries and provides relevant code examples. We show that Geomstats provides reliable building blocks to foster research in differential geometry and statistics, and to democratize the use of Riemannian geometry in machine learning applications. The source code is freely available under the MIT license at \url{geomstats.ai}.

Nicolas Guigui, Pamela Moceri, Maxime Sermesant et al.

In cases of pressure or volume overload, probing cardiac function may be difficult because of the interactions between shape and deformations.In this work, we use the LDDMM framework and parallel transport to estimate and reorient deformations of the right ventricle. We then propose a normalization procedure for the amplitude of the deformation, and a second-order spline model to represent the full cardiac contraction. The method is applied to 3D meshes of the right ventricle extracted from echocardiographic sequences of 314 patients divided into three disease categories and a control group. We find significant differences between pathologies in the model parameters, revealing insights into the dynamics of each disease.

Alice Le Brigant, Nicolas Guigui, Sana Rebbah et al.

In this paper, we use tools of information geometry to compare, average and classify histograms. Beta distributions are fitted to the histograms and the corresponding Fisher information geometry is used for comparison. We show that this geometry is negatively curved, which guarantees uniqueness of the notion of mean, and makes it suitable to classify histograms through the popular K-means algorithm. We illustrate the use of these geometric tools in supervised and unsupervised classification procedures of two medical data-sets, cardiac shape deformations for the detection of pulmonary hypertension and brain cortical thickness for the diagnosis of Alzheimer's disease.