Ge Lin

Lin Ge, Jitao Wang, Chengchun Shi et al.

Mediation analysis learns the causal effect transmitted via mediator variables between treatments and outcomes and receives increasing attention in various scientific domains to elucidate causal relations. Most existing works focus on point-exposure studies where each subject only receives one treatment at a single time point. However, there are a number of applications (e.g., mobile health) where the treatments are sequentially assigned over time and the dynamic mediation effects are of primary interest. Proposing a reinforcement learning (RL) framework, we are the first to evaluate dynamic mediation effects in settings with infinite horizons. We decompose the average treatment effect into an immediate direct effect, an immediate mediation effect, a delayed direct effect, and a delayed mediation effect. Upon the identification of each effect component, we further develop robust and semi-parametrically efficient estimators under the RL framework to infer these causal effects. The superior performance of the proposed method is demonstrated through extensive numerical studies, theoretical results, and an analysis of a mobile health dataset.

Haitao Jiang, Lin Ge, Yuhe Gao et al.

Large Language Models (LLMs) have shown their success in language understanding and reasoning on general topics. However, their capability to perform inference based on user-specified structured data and knowledge in corpus-rare concepts, such as causal decision-making is still limited. In this work, we explore the possibility of fine-tuning an open-sourced LLM into LLM4Causal, which can identify the causal task, execute a corresponding function, and interpret its numerical results based on users' queries and the provided dataset. Meanwhile, we propose a data generation process for more controllable GPT prompting and present two instruction-tuning datasets: (1) Causal-Retrieval-Bench for causal problem identification and input parameter extraction for causal function calling and (2) Causal-Interpret-Bench for in-context causal interpretation. By conducting end-to-end evaluations and two ablation studies, we showed that LLM4Causal can deliver end-to-end solutions for causal problems and provide easy-to-understand answers, which significantly outperforms the baselines.

Runzhe Wan, Lin Ge, Rui Song

Online learning in large-scale structured bandits is known to be challenging due to the curse of dimensionality. In this paper, we propose a unified meta-learning framework for a general class of structured bandit problems where the parameter space can be factorized to item-level. The novel bandit algorithm is general to be applied to many popular problems,scalable to the huge parameter and action spaces, and robust to the specification of the generalization model. At the core of this framework is a Bayesian hierarchical model that allows information sharing among items via their features, upon which we design a meta Thompson sampling algorithm. Three representative examples are discussed thoroughly. Both theoretical analysis and numerical results support the usefulness of the proposed method.

Lin Ge, Xinming An, Donglin Zeng et al.

Adverse posttraumatic neuropsychiatric sequelae (APNS) are common among veterans and millions of Americans after traumatic exposures, resulting in substantial burdens for trauma survivors and society. Despite numerous studies conducted on APNS over the past decades, there has been limited progress in understanding the underlying neurobiological mechanisms due to several unique challenges. One of these challenges is the reliance on subjective self-report measures to assess APNS, which can easily result in measurement errors and biases (e.g., recall bias). To mitigate this issue, in this paper, we investigate the potential of leveraging the objective longitudinal mobile device data to identify homogeneous APNS states and study the dynamic transitions and potential risk factors of APNS after trauma exposure. To handle specific challenges posed by longitudinal mobile device data, we developed exploratory hidden Markov factor models and designed a Stabilized Expectation-Maximization algorithm for parameter estimation. Simulation studies were conducted to evaluate the performance of parameter estimation and model selection. Finally, to demonstrate the practical utility of the method, we applied it to mobile device data collected from the Advancing Understanding of RecOvery afteR traumA (AURORA) study.