Charles N. John

Ali Imran, Iryna Posokhova, Haneya N. Qureshi et al.

Background: The inability to test at scale has become humanity's Achille's heel in the ongoing war against the COVID-19 pandemic. A scalable screening tool would be a game changer. Building on the prior work on cough-based diagnosis of respiratory diseases, we propose, develop and test an Artificial Intelligence (AI)-powered screening solution for COVID-19 infection that is deployable via a smartphone app. The app, named AI4COVID-19 records and sends three 3-second cough sounds to an AI engine running in the cloud, and returns a result within two minutes. Methods: Cough is a symptom of over thirty non-COVID-19 related medical conditions. This makes the diagnosis of a COVID-19 infection by cough alone an extremely challenging multidisciplinary problem. We address this problem by investigating the distinctness of pathomorphological alterations in the respiratory system induced by COVID-19 infection when compared to other respiratory infections. To overcome the COVID-19 cough training data shortage we exploit transfer learning. To reduce the misdiagnosis risk stemming from the complex dimensionality of the problem, we leverage a multi-pronged mediator centered risk-averse AI architecture. Results: Results show AI4COVID-19 can distinguish among COVID-19 coughs and several types of non-COVID-19 coughs. The accuracy is promising enough to encourage a large-scale collection of labeled cough data to gauge the generalization capability of AI4COVID-19. AI4COVID-19 is not a clinical grade testing tool. Instead, it offers a screening tool deployable anytime, anywhere, by anyone. It can also be a clinical decision assistance tool used to channel clinical-testing and treatment to those who need it the most, thereby saving more lives.

Charles Bales, Muhammad Nabeel, Charles N. John et al.

Emerging wireless technologies, such as 5G and beyond, are bringing new use cases to the forefront, one of the most prominent being machine learning empowered health care. One of the notable modern medical concerns that impose an immense worldwide health burden are respiratory infections. Since cough is an essential symptom of many respiratory infections, an automated system to screen for respiratory diseases based on raw cough data would have a multitude of beneficial research and medical applications. In literature, machine learning has already been successfully used to detect cough events in controlled environments. In this paper, we present a low complexity, automated recognition and diagnostic tool for screening respiratory infections that utilizes Convolutional Neural Networks (CNNs) to detect cough within environment audio and diagnose three potential illnesses (i.e., bronchitis, bronchiolitis and pertussis) based on their unique cough audio features. Both proposed detection and diagnosis models achieve an accuracy of over 89%, while also remaining computationally efficient. Results show that the proposed system is successfully able to detect and separate cough events from background noise. Moreover, the proposed single diagnosis model is capable of distinguishing between different illnesses without the need of separate models.