Ziteng Li

Ziteng Li, Malte Kuhlmann, Ilana Nisky et al.

Compliance is a critical parameter for describing objects in engineering, agriculture, and biomedical applications. Traditional compliance detection methods are limited by their lack of portability and scalability, rely on specialized, often expensive equipment, and are unsuitable for robotic applications. Moreover, existing neural network-based approaches using vision-based tactile sensors still suffer from insufficient prediction accuracy. In this paper, we propose two models based on Long-term Recurrent Convolutional Networks (LRCNs) and Transformer architectures that leverage RGB tactile images and other information captured by the vision-based sensor GelSight to predict compliance metrics accurately. We validate the performance of these models using multiple metrics and demonstrate their effectiveness in accurately estimating compliance. The proposed models exhibit significant performance improvement over the baseline. Additionally, we investigated the correlation between sensor compliance and object compliance estimation, which revealed that objects that are harder than the sensor are more challenging to estimate.

Till Rossner, Ziteng Li, Jonas Balke et al.

AI-driven drug response prediction holds great promise for advancing personalized cancer treatment. However, the inherent heterogenity of cancer and high cost of data generation make accurate prediction challenging. In this study, we investigate whether incorporating the pretrained foundation model scGPT can enhance the performance of existing drug response prediction frameworks. Our approach builds on the DeepCDR framework, which encodes drug representations from graph structures and cell representations from multi-omics profiles. We adapt this framework by leveraging scGPT to generate enriched cell representations using its pretrained knowledge to compensate for limited amount of data. We evaluate our modified framework using IC$_{50}$ values on Pearson correlation coefficient (PCC) and a leave-one-drug out validation strategy, comparing it against the original DeepCDR framework and a prior scFoundation-based approach. scGPT not only outperforms previous approaches but also exhibits greater training stability, highlighting the value of leveraging scGPT-derived knowledge in this domain.