Minh Hoang Le

Khang Le, Ha Thach, Anh M. Vu et al.

Weakly supervised semantic segmentation (WSSS) in histopathology relies heavily on classification backbones, yet these models often localize only the most discriminative regions and struggle to capture the full spatial extent of tissue structures. Vision-language models such as CONCH offer rich semantic alignment and morphology-aware representations, while modern segmentation backbones like SegFormer preserve fine-grained spatial cues. However, combining these complementary strengths remains challenging, especially under weak supervision and without dense annotations. We propose a prototype learning framework for WSSS in histopathological images that integrates morphology-aware representations from CONCH, multi-scale structural cues from SegFormer, and text-guided semantic alignment to produce prototypes that are simultaneously semantically discriminative and spatially coherent. To effectively leverage these heterogeneous sources, we introduce text-guided prototype initialization that incorporates pathology descriptions to generate more complete and semantically accurate pseudo-masks. A structural distillation mechanism transfers spatial knowledge from SegFormer to preserve fine-grained morphological patterns and local tissue boundaries during prototype learning. Our approach produces high-quality pseudo masks without pixel-level annotations, improves localization completeness, and enhances semantic consistency across tissue types. Experiments on BCSS-WSSS datasets demonstrate that our prototype learning framework outperforms existing WSSS methods while remaining computationally efficient through frozen foundation model backbones and lightweight trainable adapters.

Anh M. Vu, Khang P. Le, Trang T. K. Vo et al.

Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage effect of CAM-based supervision. We propose a simple and effective prototype-driven framework that leverages vision-language alignment to improve region discovery under weak supervision. Our method integrates CoOp-style learnable prompt tuning to generate text-based prototypes and combines them with learnable image prototypes, forming a dual-modal prototype bank that captures both semantic and appearance cues. To address oversmoothing in ViT representations, we incorporate a multi-scale pyramid module that enhances spatial precision and improves localization quality. Experiments on the BCSS-WSSS benchmark show that our approach surpasses existing state-of-the-art methods, and detailed analyses demonstrate the benefits of text description diversity, context length, and the complementary behavior of text and image prototypes. These results highlight the effectiveness of jointly leveraging textual semantics and visual prototype learning for WSSS in digital pathology.

Huu-Loc Tran, Tinh-Anh Nguyen-Nhu, Huu-Phong Phan-Nguyen et al.

Long-form video understanding presents significant challenges for interactive retrieval systems, as conventional methods struggle to process extensive video content efficiently. Existing approaches often rely on single models, inefficient storage, unstable temporal search, and context-agnostic reranking, limiting their effectiveness. This paper presents a novel framework to enhance interactive video retrieval through four key innovations: (1) an ensemble search strategy that integrates coarse-grained (CLIP) and fine-grained (BEIT3) models to improve retrieval accuracy, (2) a storage optimization technique that reduces redundancy by selecting representative keyframes via TransNetV2 and deduplication, (3) a temporal search mechanism that localizes video segments using dual queries for start and end points, and (4) a temporal reranking approach that leverages neighboring frame context to stabilize rankings. Evaluated on known-item search and question-answering tasks, our framework demonstrates substantial improvements in retrieval precision, efficiency, and user interpretability, offering a robust solution for real-world interactive video retrieval applications.

Khang Le, Anh Mai Vu, Thi Kim Trang Vo et al.

Weakly supervised semantic segmentation (WSSS) in histopathology reduces pixel-level labeling by learning from image-level labels, but it is hindered by inter-class homogeneity, intra-class heterogeneity, and CAM-induced region shrinkage (global pooling-based class activation maps whose activations highlight only the most distinctive areas and miss nearby class regions). Recent works address these challenges by constructing a clustering prototype bank and then refining masks in a separate stage; however, such two-stage pipelines are costly, sensitive to hyperparameters, and decouple prototype discovery from segmentation learning, limiting their effectiveness and efficiency. We propose a cluster-free, one-stage learnable-prototype framework with diversity regularization to enhance morphological intra-class heterogeneity coverage. Our approach achieves state-of-the-art (SOTA) performance on BCSS-WSSS, outperforming prior methods in mIoU and mDice. Qualitative segmentation maps show sharper boundaries and fewer mislabels, and activation heatmaps further reveal that, compared with clustering-based prototypes, our learnable prototypes cover more diverse and complementary regions within each class, providing consistent qualitative evidence for their effectiveness.

Minh Le, Bao-Ngoc Dao, Huy Nguyen et al.

Prompt-based methods have recently gained prominence in Continual Learning (CL) due to their strong performance and memory efficiency. A prevalent strategy in this paradigm assigns a dedicated subset of prompts to each task, which, while effective, incurs substantial computational overhead and causes memory requirements to scale linearly with the number of tasks. Conversely, approaches employing a single shared prompt across tasks offer greater efficiency but often suffer from degraded performance due to knowledge interference. To reconcile this trade-off, we propose SMoPE, a novel framework that integrates the benefits of both task-specific and shared prompt strategies. Inspired by recent findings on the relationship between Prefix Tuning and Mixture of Experts (MoE), SMoPE organizes a shared prompt into multiple "prompt experts" within a sparse MoE architecture. For each input, only a select subset of relevant experts is activated, effectively mitigating interference. To facilitate expert selection, we introduce a prompt-attention score aggregation mechanism that computes a unified proxy score for each expert, enabling dynamic and sparse activation. Additionally, we propose an adaptive noise mechanism to encourage balanced expert utilization while preserving knowledge from prior tasks. To further enhance expert specialization, we design a prototype-based loss function that leverages prefix keys as implicit memory representations. Extensive experiments across multiple CL benchmarks demonstrate that SMoPE consistently outperforms task-specific prompt methods and achieves performance competitive with state-of-the-art approaches, all while significantly reducing parameter counts and computational costs.