Xinyu Li

Bo Peng, Xiaofeng Li, Xinyu Li et al.

Hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis (CA) are both heart conditions that can progress to heart failure if untreated. They exhibit similar echocardiographic characteristics, often leading to diagnostic challenges. This paper introduces a novel multi-view deep learning approach that utilizes 2D echocardiography for differentiating between HCM and CA. The method begins by classifying 2D echocardiography data into five distinct echocardiographic views: apical 4-chamber, parasternal long axis of left ventricle, parasternal short axis at levels of the mitral valve, papillary muscle, and apex. It then extracts features of each view separately and combines five features for disease classification. A total of 212 patients diagnosed with HCM, and 30 patients diagnosed with CA, along with 200 individuals with normal cardiac function(Normal), were enrolled in this study from 2018 to 2022. This approach achieved a precision, recall of 0.905, and micro-F1 score of 0.904, demonstrating its effectiveness in accurately identifying HCM and CA using a multi-view analysis.

Mingda Li, Xinyu Li, Weinan Zhang et al.

Uncertainty Quantification (UQ) is a promising approach to improve model reliability, yet quantifying the uncertainty of Large Language Models (LLMs) is non-trivial. In this work, we establish a connection between the uncertainty of LLMs and their invariance under semantic-preserving intervention from a causal perspective. Building on this foundation, we propose a novel grey-box uncertainty quantification method that measures the variation in model outputs before and after the semantic-preserving intervention. Through theoretical justification, we show that our method provides an effective estimate of epistemic uncertainty. Our extensive experiments, conducted across various LLMs and a variety of question-answering (QA) datasets, demonstrate that our method excels not only in terms of effectiveness but also in computational efficiency.