Correlation-based Discovery of Disease Patterns for Syndromic SurveillanceMichael Rapp, Moritz Kulessa, Eneldo Loza Mencía et al.
Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected increases of infections by monitoring confirmed cases, syndromic surveillance aims at the detection of cases with early symptoms, which allows a more timely disclosure of outbreaks. However, the definition of these disease patterns is often challenging, as early symptoms are usually shared among many diseases and a particular disease can have several clinical pictures in the early phase of an infection. To support epidemiologists in the process of defining reliable disease patterns, we present a novel, data-driven approach to discover such patterns in historic data. The key idea is to take into account the correlation between indicators in a health-related data source and the reported number of infections in the respective geographic region. In an experimental evaluation, we use data from several emergency departments to discover disease patterns for three infectious diseases. Our results suggest that the proposed approach is able to find patterns that correlate with the reported infections and often identifies indicators that are related to the respective diseases.
3.3LGNov 2, 2020
A Flexible Class of Dependence-aware Multi-Label Loss FunctionsEyke Hüllermeier, Marcel Wever, Eneldo Loza Mencia et al.
Multi-label classification is the task of assigning a subset of labels to a given query instance. For evaluating such predictions, the set of predicted labels needs to be compared to the ground-truth label set associated with that instance, and various loss functions have been proposed for this purpose. In addition to assessing predictive accuracy, a key concern in this regard is to foster and to analyze a learner's ability to capture label dependencies. In this paper, we introduce a new class of loss functions for multi-label classification, which overcome disadvantages of commonly used losses such as Hamming and subset 0/1. To this end, we leverage the mathematical framework of non-additive measures and integrals. Roughly speaking, a non-additive measure allows for modeling the importance of correct predictions of label subsets (instead of single labels), and thereby their impact on the overall evaluation, in a flexible way - by giving full importance to single labels and the entire label set, respectively, Hamming and subset 0/1 are rather extreme in this regard. We present concrete instantiations of this class, which comprise Hamming and subset 0/1 as special cases, and which appear to be especially appealing from a modeling perspective. The assessment of multi-label classifiers in terms of these losses is illustrated in an empirical study.
Efficient Discovery of Expressive Multi-label Rules using Relaxed PruningYannik Klein, Michael Rapp, Eneldo Loza Mencía
Being able to model correlations between labels is considered crucial in multi-label classification. Rule-based models enable to expose such dependencies, e.g., implications, subsumptions, or exclusions, in an interpretable and human-comprehensible manner. Albeit the number of possible label combinations increases exponentially with the number of available labels, it has been shown that rules with multiple labels in their heads, which are a natural form to model local label dependencies, can be induced efficiently by exploiting certain properties of rule evaluation measures and pruning the label search space accordingly. However, experiments have revealed that multi-label heads are unlikely to be learned by existing methods due to their restrictiveness. To overcome this limitation, we propose a plug-in approach that relaxes the search space pruning used by existing methods in order to introduce a bias towards larger multi-label heads resulting in more expressive rules. We further demonstrate the effectiveness of our approach empirically and show that it does not come with drawbacks in terms of training time or predictive performance.