Karanpartap Singh

Kasra Naftchi-Ardebili, Karanpartap Singh, Reza Pourabolghasem et al.

Deep learning offers potential for various healthcare applications, yet requires extensive datasets of curated medical images where data privacy, cost, and distribution mismatch across various acquisition centers could become major problems. To overcome these challenges, we propose a generative adversarial network (SkullGAN) to create large datasets of synthetic skull CT slices, geared towards training models for transcranial ultrasound. With wide ranging applications in treatment of essential tremor, Parkinson's, and Alzheimer's disease, transcranial ultrasound clinical pipelines can be significantly optimized via integration of deep learning. The main roadblock is the lack of sufficient skull CT slices for the purposes of training, which SkullGAN aims to address. Actual CT slices of 38 healthy subjects were used for training. The generated synthetic skull images were then evaluated based on skull density ratio, mean thickness, and mean intensity. Their fidelity was further analyzed using t-distributed stochastic neighbor embedding (t-SNE), Fréchet inception distance (FID) score, and visual Turing test (VTT) taken by four staff clinical radiologists. SkullGAN-generated images demonstrated similar quantitative radiological features to real skulls. t-SNE failed to separate real and synthetic samples from one another, and the FID score was 49. Expert radiologists achieved a 60\% mean accuracy on the VTT. SkullGAN makes it possible for researchers to generate large numbers of synthetic skull CT segments, necessary for training neural networks for medical applications involving the human skull, such as transcranial focused ultrasound, mitigating challenges with access, privacy, capital, time, and the need for domain expertise.

Karanpartap Singh, James Zou

With the increasing use of large-language models (LLMs) like ChatGPT, watermarking has emerged as a promising approach for tracing machine-generated content. However, research on LLM watermarking often relies on simple perplexity or diversity-based measures to assess the quality of watermarked text, which can mask important limitations in watermarking. Here we introduce two new easy-to-use methods for evaluating watermarking algorithms for LLMs: 1) evaluation by LLM-judger with specific guidelines; and 2) binary classification on text embeddings to distinguish between watermarked and unwatermarked text. We apply these methods to characterize the effectiveness of current watermarking techniques. Our experiments, conducted across various datasets, reveal that current watermarking methods are detectable by even simple classifiers, challenging the notion of watermarking subtlety. We also found, through the LLM judger, that watermarking impacts text quality, especially in degrading the coherence and depth of the response. Our findings underscore the trade-off between watermark robustness and text quality and highlight the importance of having more informative metrics to assess watermarking quality.

Karanpartap Singh, Neil Band, Ehsan Adeli

As the cost of pretraining large language models grows, there is continued interest in strategies to improve learning efficiency during this core training stage. Motivated by cognitive development, where humans gradually build knowledge as their brains mature, we propose Curriculum-Guided Layer Scaling (CGLS), a framework for compute-efficient pretraining that synchronizes increasing data difficulty with model growth through progressive layer stacking (i.e. gradually adding layers during training). At the 100M parameter scale, using a curriculum transitioning from synthetic short stories to general web data, CGLS outperforms baseline methods on the question-answering benchmarks PIQA and ARC. Pretraining at the 1.2B scale, we stratify the DataComp-LM corpus with a DistilBERT-based classifier and progress from general text to highly technical or specialized content. Our results show that progressively increasing model depth alongside sample difficulty leads to better generalization and zero-shot performance on various downstream benchmarks. Altogether, our findings demonstrate that CGLS unlocks the potential of progressive stacking, offering a simple yet effective strategy for improving generalization on knowledge-intensive and reasoning tasks.