Giuseppe Patanè

Martina Paccini, Giuseppe Patanè, Michela Spagnuolo

This work addresses the patient-specific characterisation of the morphology and pathologies of muscle-skeletal districts (e.g., wrist, spine) to support diagnostic activities and follow-up exams through the integration of morphological and tissue information. We propose different methods for the integration of morphological information, retrieved from the geometrical analysis of 3D surface models, with tissue information extracted from volume images. For the qualitative and quantitative validation, we will discuss the localisation of bone erosion sites on the wrists to monitor rheumatic diseases and the characterisation of the three functional regions of the spinal vertebrae to study the presence of osteoporotic fractures. The proposed approach supports the quantitative and visual evaluation of possible damages, surgery planning, and early diagnosis or follow-up studies. Finally, our analysis is general enough to be applied to different districts.

Martina Paccini, Giacomo Paschina, Stefano De Beni et al.

This paper presents an innovative automatic fusion imaging system that combines 3D CT/MR images with real-time ultrasound (US) acquisition. The system eliminates the need for external physical markers and complex training, making image fusion feasible for physicians with different experience levels. The integrated system involves a portable 3D camera for patient-specific surface acquisition, an electromagnetic tracking system, and US components. The fusion algorithm comprises two main parts: skin segmentation and rigid co-registration, both integrated into the US machine. The co-registration software aligns the surface extracted from CT/MR images with patient-specific coordinates, facilitating rapid and effective fusion. Experimental testing in different settings validates the system's accuracy, computational efficiency, noise robustness, and operator independence. The co-registration error remains under the acceptable range of~$1$ cm.

Simone Cammarasana, Paolo Nicolardi, Giuseppe Patanè

We propose a novel deep-learning framework for super-resolution ultrasound images and videos in terms of spatial resolution and line reconstruction. We up-sample the acquired low-resolution image through a vision-based interpolation method; then, we train a learning-based model to improve the quality of the up-sampling. We qualitatively and quantitatively test our model on different anatomical districts (e.g., cardiac, obstetric) images and with different up-sampling resolutions (i.e., 2X, 4X). Our method improves the PSNR median value with respect to SOTA methods of $1.7\%$ on obstetric 2X raw images, $6.1\%$ on cardiac 2X raw images, and $4.4\%$ on abdominal raw 4X images; it also improves the number of pixels with a low prediction error of $9.0\%$ on obstetric 4X raw images, $5.2\%$ on cardiac 4X raw images, and $6.2\%$ on abdominal 4X raw images. The proposed method is then applied to the spatial super-resolution of 2D videos, by optimising the sampling of lines acquired by the probe in terms of the acquisition frequency. Our method specialises trained networks to predict the high-resolution target through the design of the network architecture and the loss function, taking into account the anatomical district and the up-sampling factor and exploiting a large ultrasound data set. The use of deep learning on large data sets overcomes the limitations of vision-based algorithms that are general and do not encode the characteristics of the data. Furthermore, the data set can be enriched with images selected by medical experts to further specialise the individual networks. Through learning and high-performance computing, our super-resolution is specialised to different anatomical districts by training multiple networks. Furthermore, the computational demand is shifted to centralised hardware resources with a real-time execution of the network's prediction on local devices.

Simone Cammarasana, Giuseppe Patanè

Several applications require the super-resolution of noisy images and the preservation of geometrical and texture features. State-of-the-art super-resolution methods do not account for noise and generally enhance the output image's artefacts (e.g., aliasing, blurring). We propose a learning-based method that accounts for the presence of noise and preserves the properties of the input image, as measured by quantitative metrics (e.g., normalised crossed correlation, normalised mean squared error, peak-signal-to-noise-ration, structural similarity feature-based similarity, universal image quality). We train our network to up-sample a low-resolution noisy image while preserving its properties. We perform our tests on the Cineca Marconi100 cluster, at the 26th position in the top500 list. The experimental results show that our method outperforms learning-based methods, has comparable results with standard methods, preserves the properties of the input image as contours, brightness, and textures, and reduces the artefacts. As average quantitative metrics, our method has a PSNR value of 23.81 on the super-resolution of Gaussian noise images with a 2X up-sampling factor. In contrast, previous work has a PSNR value of 23.09 (standard method) and 21.78 (learning-based method). Our learning-based and quality-preserving super-resolution improves the high-resolution prediction of noisy images with respect to state-of-the-art methods with different noise types and up-sampling factors.

Simone Cammarasana, Giuseppe Patanè

We introduce a novel weighted convolution operator that enhances traditional convolutional neural networks (CNNs) by integrating a spatial density function into the convolution operator. This extension enables the network to differentially weight neighbouring pixels based on their relative position to the reference pixel, improving spatial characterisation and feature extraction. The proposed operator maintains the same number of trainable parameters and is fully compatible with existing CNN architectures. Although developed for 2D image data, the framework is generalisable to signals on regular grids of arbitrary dimensions, such as 3D volumetric data or 1D time series. We propose an efficient implementation of the weighted convolution by pre-computing the density function and achieving execution times comparable to standard convolution layers. We evaluate our method on two deep learning tasks: image classification using the CIFAR-100 dataset [KH+09] and image denoising using the DIV2K dataset [AT17]. Experimental results with state-of-the-art classification (e.g., VGG [SZ15], ResNet [HZRS16]) and denoising (e.g., DnCNN [ZZC+17], NAFNet [CCZS22]) methods show that the weighted convolution improves performance with respect to standard convolution across different quantitative metrics. For example, VGG achieves an accuracy of 66.94% with weighted convolution versus 56.89% with standard convolution on the classification problem, while DnCNN improves the PSNR value from 20.17 to 22.63 on the denoising problem. All models were trained on the CINECA Leonardo cluster to reduce the execution time and improve the tuning of the density function values. The PyTorch implementation of the weighted convolution is publicly available at: https://github.com/cammarasana123/weightedConvolution2.0.

Daniele Di Mauro, Antonino Furnari, Giuseppe Patanè et al.

Semantic segmentation methods have achieved outstanding performance thanks to deep learning. Nevertheless, when such algorithms are deployed to new contexts not seen during training, it is necessary to collect and label scene-specific data in order to adapt them to the new domain using fine-tuning. This process is required whenever an already installed camera is moved or a new camera is introduced in a camera network due to the different scene layouts induced by the different viewpoints. To limit the amount of additional training data to be collected, it would be ideal to train a semantic segmentation method using labeled data already available and only unlabeled data coming from the new camera. We formalize this problem as a domain adaptation task and introduce a novel dataset of urban scenes with the related semantic labels. As a first approach to address this challenging task, we propose SceneAdapt, a method for scene adaptation of semantic segmentation algorithms based on adversarial learning. Experiments and comparisons with state-of-the-art approaches to domain adaptation highlight that promising performance can be achieved using adversarial learning both when the two scenes have different but points of view, and when they comprise images of completely different scenes. To encourage research on this topic, we made our code available at our web page: https://iplab.dmi.unict.it/ParkSmartSceneAdaptation/.

Martina Paccini, Simone Cammarasana, Giuseppe Patanè

Musculoskeletal disorders (MSDs) are a leading cause of disability worldwide, requiring advanced diagnostic and therapeutic tools for personalised assessment and treatment. Effective management of MSDs involves the interaction of heterogeneous data sources, making the Digital Twin (DT) paradigm a valuable option. This paper introduces the Musculoskeletal Digital Twin (MS-DT), a novel framework that integrates multiscale biomechanical data with computational modelling to create a detailed, patient-specific representation of the musculoskeletal system. By combining motion capture, ultrasound imaging, electromyography, and medical imaging, the MS-DT enables the analysis of spinal kinematics, posture, and muscle function. An interactive visualisation platform provides clinicians and researchers with an intuitive interface for exploring biomechanical parameters and tracking patient-specific changes. Results demonstrate the effectiveness of MS-DT in extracting precise kinematic and dynamic tissue features, offering a comprehensive tool for monitoring spine biomechanics and rehabilitation. This framework provides high-fidelity modelling and real-time visualization to improve patient-specific diagnosis and intervention planning.

Simone Cammarasana, Giuseppe Patanè

The paper introduces the weighted convolution, a novel approach to the convolution for signals defined on regular grids (e.g., 2D images) through the application of an optimal density function to scale the contribution of neighbouring pixels based on their distance from the central pixel. This choice differs from the traditional uniform convolution, which treats all neighbouring pixels equally. Our weighted convolution can be applied to convolutional neural network problems to improve the approximation accuracy. Given a convolutional network, we define a framework to compute the optimal density function through a minimisation model. The framework separates the optimisation of the convolutional kernel weights (using stochastic gradient descent) from the optimisation of the density function (using DIRECT-L). Experimental results on a learning model for an image-to-image task (e.g., image denoising) show that the weighted convolution significantly reduces the loss (up to 53% improvement) and increases the test accuracy compared to standard convolution. While this method increases execution time by 11%, it is robust across several hyperparameters of the learning model. Future work will apply the weighted convolution to real-case 2D and 3D image convolutional learning problems.

Davide Micale, Gianpiero Costantino, Ilaria Matteucci et al.

The introduction of Information and Communication Technology (ICT) in transportation systems leads to several advantages (efficiency of transport, mobility, traffic management). However, it may bring some drawbacks in terms of increasing security challenges, also related to human behaviour. As an example , in the last decades attempts to characterize drivers' behaviour have been mostly targeted. This paper presents Secure Routine, a paradigm that uses driver's habits to driver identification and, in particular, to distinguish the vehicle's owner from other drivers. We evaluate Secure Routine in combination with other three existing research works based on machine learning techniques. Results are measured using well-known metrics and show that Secure Routine outperforms the compared works.

Simone Cammarasana, Paolo Nicolardi, Giuseppe Patanè

Ultrasound images are widespread in medical diagnosis for muscle-skeletal, cardiac, and obstetrical diseases, due to the efficiency and non-invasiveness of the acquisition methodology. However, ultrasound acquisition introduces noise in the signal, which corrupts the resulting image and affects further processing steps, e.g., segmentation and quantitative analysis. We define a novel deep learning framework for the real-time denoising of ultrasound images. Firstly, we compare state-of-the-art methods for denoising (e.g., spectral, low-rank methods) and select WNNM (Weighted Nuclear Norm Minimisation) as the best denoising in terms of accuracy, preservation of anatomical features, and edge enhancement. Then, we propose a tuned version of WNNM (tuned-WNNM) that improves the quality of the denoised images and extends its applicability to ultrasound images. Through a deep learning framework, the tuned-WNNM qualitatively and quantitatively replicates WNNM results in real-time. Finally, our approach is general in terms of its building blocks and parameters of the deep learning and high-performance computing framework; in fact, we can select different denoising algorithms and deep learning architectures.

Giuseppe Patanè

Data are represented as graphs in a wide range of applications, such as Computer Vision (e.g., images) and Graphics (e.g., 3D meshes), network analysis (e.g., social networks), and bio-informatics (e.g., molecules). In this context, our overall goal is the definition of novel Fourier-based and graph filters induced by rational polynomials for graph processing, which generalise polynomial filters and the Fourier transform to non-Euclidean domains. For the efficient evaluation of discrete spectral Fourier-based and wavelet operators, we introduce a spectrum-free approach, which requires the solution of a small set of sparse, symmetric, well-conditioned linear systems and is oblivious of the evaluation of the Laplacian or kernel spectrum. Approximating arbitrary graph filters with rational polynomials provides a more accurate and numerically stable alternative with respect to polynomials. To achieve these goals, we also study the link between spectral operators, wavelets, and filtered convolution with integral operators induced by spectral kernels. According to our tests, main advantages of the proposed approach are (i) its generality with respect to the input data (e.g., graphs, 3D shapes), applications (e.g., signal reconstruction and smoothing, shape correspondence), and filters (e.g., polynomial, rational polynomial), and (ii) a spectrum-free computation with a generally low computational cost and storage overhead.