Cesare Hassan

Mauro Orazio Drago, Luca Carlini, Pelinsu Celebi Balyemez et al.

Video Question Answering (VideoQA) in the surgical domain aims to enhance intraoperative understanding by enabling AI models to reason over temporally coherent events rather than isolated frames. Current approaches are limited to static image features, and available datasets often lack temporal annotations, ignoring the dynamics critical for accurate procedural interpretation. We propose SurgViVQA, a surgical VideoQA model that extends visual reasoning from static images to dynamic surgical scenes. It uses a Masked Video--Text Encoder to fuse video and question features, capturing temporal cues such as motion and tool--tissue interactions, which a fine-tuned large language model (LLM) then decodes into coherent answers. To evaluate its performance, we curated REAL-Colon-VQA, a colonoscopic video dataset that includes motion-related questions and diagnostic attributes, as well as out-of-template questions with rephrased or semantically altered formulations to assess model robustness. Experimental validation on REAL-Colon-VQA and the public EndoVis18-VQA dataset shows that SurgViVQA outperforms existing image-based VQA benchmark models, particularly in keyword accuracy, improving over PitVQA by +11\% on REAL-Colon-VQA and +9\% on EndoVis18-VQA. A perturbation study on the questions further confirms improved generalizability and robustness to variations in question phrasing. SurgViVQA and the REAL-Colon-VQA dataset provide a framework for temporally-aware understanding in surgical VideoQA, enabling AI models to interpret dynamic procedural contexts more effectively. Code and dataset available at https://github.com/madratak/SurgViVQA.

Dennis Pierantozzi, Luca Carlini, Mauro Orazio Drago et al.

Safety and reliability are essential for deploying Visual Question Answering (VQA) in surgery, where incorrect or ambiguous responses can harm the patient. Most surgical VQA research focuses on accuracy or linguistic quality while overlooking safety behaviors such as ambiguity awareness, referral to human experts, or triggering a second opinion. Inspired by Automatic Failure Detection (AFD), we study uncertainty estimation as a key enabler of safer decision making. We introduce Question Aligned Semantic Nearest Neighbor Entropy (QA-SNNE), a black box uncertainty estimator that incorporates question semantics into prediction confidence. It measures semantic entropy by comparing generated answers with nearest neighbors in a medical text embedding space, conditioned on the question. We evaluate five models, including domain specific Parameter-Efficient Fine-Tuned (PEFT) models and zero-shot Large Vision-Language Models (LVLMs), on EndoVis18-VQA and PitVQA. PEFT models degrade under mild paraphrasing, while LVLMs are more resilient. Across three LVLMs and two PEFT baselines, QA-SNNE improves AUROC in most in-template settings and enhances hallucination detection. The Area Under the ROC Curve (AUROC) increases by 15-38% for zero-shot models, with gains maintained under out-of-template stress. QA-SNNE offers a practical and interpretable step toward AFD in surgical VQA by linking semantic uncertainty to question context. Combining LVLM backbones with question aligned uncertainty estimation can improve safety and clinician trust. The code and model are available at https://github.com/DennisPierantozzi/QASNNE

Luca Carlini, Chiara Lena, Cesare Hassan et al.

Surgical Video Question Answering (VideoQA) requires accurate temporal grounding while remaining robust to natural variation in how clinicians phrase questions, where linguistic bias can arise. Standard Parameter Efficient Fine Tuning (PEFT) methods adapt pretrained projections without explicitly modeling frame-to-frame interactions within the adaptation pathway, limiting their ability to exploit sparse temporal evidence. We introduce TemporalDoRA, a video-specific PEFT formulation that extends Weight-Decomposed Low-Rank Adaptation by (i) inserting lightweight temporal Multi-Head Attention (MHA) inside the low-rank bottleneck of the vision encoder and (ii) selectively applying weight decomposition only to the trainable low-rank branch rather than the full adapted weight. This design enables temporally-aware updates while preserving a frozen backbone and stable scaling. By mixing information across frames within the adaptation subspace, TemporalDoRA steers updates toward temporally consistent visual cues and improves robustness with minimal parameter overhead. To benchmark this setting, we present REAL-Colon-VQA, a colonoscopy VideoQA dataset with 6,424 clip--question pairs, including paired rephrased Out-of-Template questions to evaluate sensitivity to linguistic variation. TemporalDoRA improves Out-of-Template performance, and ablation studies confirm that temporal mixing inside the low-rank branch is the primary driver of these gains. We also validate on EndoVis18-VQA adapted to short clips and observe consistent improvements on the Out-of-Template split. Code and dataset available at~\href{https://anonymous.4open.science/r/TemporalDoRA-BFC8/}{Anonymous GitHub}.

Chiara Lena, Davide Milesi, Alessandro Casella et al.

Deep learning has the potential to improve colonoscopy by enabling 3D reconstruction of the colon, providing a comprehensive view of mucosal surfaces and lesions, and facilitating the identification of unexplored areas. However, the development of robust methods is limited by the scarcity of large-scale ground truth data. We propose RealSynCol, a highly realistic synthetic dataset designed to replicate the endoscopic environment. Colon geometries extracted from 10 CT scans were imported into a virtual environment that closely mimics intraoperative conditions and rendered with realistic vascular textures. The resulting dataset comprises 28\,130 frames, paired with ground truth depth maps, optical flow, 3D meshes, and camera trajectories. A benchmark study was conducted to evaluate the available synthetic colon datasets for the tasks of depth and pose estimation. Results demonstrate that the high realism and variability of RealSynCol significantly enhance generalization performance on clinical images, proving it to be a powerful tool for developing deep learning algorithms to support endoscopic diagnosis.

Carlo Biffi, Giulio Antonelli, Sebastian Bernhofer et al.

Detection and diagnosis of colon polyps are key to preventing colorectal cancer. Recent evidence suggests that AI-based computer-aided detection (CADe) and computer-aided diagnosis (CADx) systems can enhance endoscopists' performance and boost colonoscopy effectiveness. However, most available public datasets primarily consist of still images or video clips, often at a down-sampled resolution, and do not accurately represent real-world colonoscopy procedures. We introduce the REAL-Colon (Real-world multi-center Endoscopy Annotated video Library) dataset: a compilation of 2.7M native video frames from sixty full-resolution, real-world colonoscopy recordings across multiple centers. The dataset contains 350k bounding-box annotations, each created under the supervision of expert gastroenterologists. Comprehensive patient clinical data, colonoscopy acquisition information, and polyp histopathological information are also included in each video. With its unprecedented size, quality, and heterogeneity, the REAL-Colon dataset is a unique resource for researchers and developers aiming to advance AI research in colonoscopy. Its openness and transparency facilitate rigorous and reproducible research, fostering the development and benchmarking of more accurate and reliable colonoscopy-related algorithms and models.