Rundong Xue

Rizhuo Huang, Yifan Feng, Rundong Xue et al.

Knowledge hypergraphs surpass traditional binary knowledge graphs by encapsulating complex $n$-ary atomic facts, providing a more comprehensive paradigm for semantic representation. However, constructing high-quality hypergraphs remains challenging due to the \textit{scenario gap}: generic extractors struggle to generalize across diverse domains with specific jargon, while existing methods often fail to balance structural skeletons with fine-grained details. To bridge this gap, we propose \textbf{Hyper-KGGen}, a skill-driven framework that reformulates extraction as a dynamic skill-evolving process. First, Hyper-KGGen employs a \textit{coarse-to-fine} mechanism to systematically decompose documents, ensuring full-dimensional coverage from binary links to complex hyperedges. Crucially, it incorporates an \textit{adaptive skill acquisition} module that actively distills domain expertise into a Global Skill Library. This is achieved via a stability-based feedback loop, where extraction stability serves as a relative reward signal to induce high-quality skills from unstable traces and missed predictions. Additionally, we present \textbf{HyperDocRED}, a rigorously annotated benchmark for document-level knowledge hypergraph extraction. Experiments demonstrate that Hyper-KGGen significantly outperforms strong baselines, validating that evolved skills provide substantially richer guidance than static few-shot examples in multi-scenario settings.

Shengbo Tan, Rundong Xue, Shipeng Luo et al.

Hepatic vessels in computed tomography scans often suffer from image fragmentation and noise interference, making it difficult to maintain vessel integrity and posing significant challenges for vessel segmentation. To address this issue, we propose an innovative model: SegKAN. First, we improve the conventional embedding module by adopting a novel convolutional network structure for image embedding, which smooths out image noise and prevents issues such as gradient explosion in subsequent stages. Next, we transform the spatial relationships between Patch blocks into temporal relationships to solve the problem of capturing positional relationships between Patch blocks in traditional Vision Transformer models. We conducted experiments on a Hepatic vessel dataset, and compared to the existing state-of-the-art model, the Dice score improved by 1.78%. These results demonstrate that the proposed new structure effectively enhances the segmentation performance of high-resolution extended objects. Code will be available at https://github.com/goblin327/SegKAN

Zhihan Guo, Rundong Xue, Yuting Lu et al.

Novice math teachers often encounter students' mistakes that are difficult to diagnose and remediate. Misconceptions are especially challenging because teachers must explain what went wrong and how to solve them. Although many existing large language model (LLM) platforms can assist in generating instructional feedback, these LLMs loosely connect pedagogical knowledge and student mistakes, which might make the guidance less actionable for teachers. To address this gap, we propose MisEdu-RAG, a dual-hypergraph-based retrieval-augmented generation (RAG) framework that organizes pedagogical knowledge as a concept hypergraph and real student mistake cases as an instance hypergraph. Given a query, MisEdu-RAG performs a two-stage retrieval to gather connected evidence from both layers and generates a response grounded in the retrieved cases and pedagogical principles. We evaluate on \textit{MisstepMath}, a dataset of math mistakes paired with teacher solutions, as a benchmark for misconception-aware retrieval and response generation across topics and error types. Evaluation results on \textit{MisstepMath} show that, compared with baseline models, MisEdu-RAG improves token-F1 by 10.95\% and yields up to 15.3\% higher five-dimension response quality, with the largest gains on \textit{Diversity} and \textit{Empowerment}. To verify its applicability in practical use, we further conduct a pilot study through a questionnaire survey of 221 teachers and interviews with 6 novices. The findings suggest that MisEdu-RAG provides diagnosis results and concrete teaching moves for high-demand misconception scenarios. Overall, MisEdu-RAG demonstrates strong potential for scalable teacher training and AI-assisted instruction for misconception handling. Our code is available on GitHub: https://github.com/GEMLab-HKU/MisEdu-RAG.

Yang Luo, Shiru Wang, Jun Liu et al.

Breast cancer survival prediction in computational pathology presents a remarkable challenge due to tumor heterogeneity. For instance, different regions of the same tumor in the pathology image can show distinct morphological and molecular characteristics. This makes it difficult to extract representative features from whole slide images (WSIs) that truly reflect the tumor's aggressive potential and likely survival outcomes. In this paper, we present PathoHR, a novel pipeline for accurate breast cancer survival prediction that enhances any size of pathological images to enable more effective feature learning. Our approach entails (1) the incorporation of a plug-and-play high-resolution Vision Transformer (ViT) to enhance patch-wise WSI representation, enabling more detailed and comprehensive feature extraction, (2) the systematic evaluation of multiple advanced similarity metrics for comparing WSI-extracted features, optimizing the representation learning process to better capture tumor characteristics, (3) the demonstration that smaller image patches enhanced follow the proposed pipeline can achieve equivalent or superior prediction accuracy compared to raw larger patches, while significantly reducing computational overhead. Experimental findings valid that PathoHR provides the potential way of integrating enhanced image resolution with optimized feature learning to advance computational pathology, offering a promising direction for more accurate and efficient breast cancer survival prediction. Code will be available at https://github.com/AIGeeksGroup/PathoHR.

Anglin Liu, Rundong Xue, Xu R. Cao et al.

Medical image segmentation is fundamental for biomedical discovery. Existing methods lack generalizability and demand extensive, time-consuming manual annotation for new clinical application. Here, we propose MedSAM-3, a text promptable medical segmentation model for medical image and video segmentation. By fine-tuning the Segment Anything Model (SAM) 3 architecture on medical images paired with semantic conceptual labels, our MedSAM-3 enables medical Promptable Concept Segmentation (PCS), allowing precise targeting of anatomical structures via open-vocabulary text descriptions rather than solely geometric prompts. We further introduce the MedSAM-3 Agent, a framework that integrates Multimodal Large Language Models (MLLMs) to perform complex reasoning and iterative refinement in an agent-in-the-loop workflow. Comprehensive experiments across diverse medical imaging modalities, including X-ray, MRI, Ultrasound, CT, and video, demonstrate that our approach significantly outperforms existing specialist and foundation models. We will release our code and model at https://github.com/Joey-S-Liu/MedSAM3.

Hongjie Zhu, Xiwei Liu, Rundong Xue et al.

In the era of information explosion, efficiently leveraging large-scale unlabeled data while minimizing the reliance on high-quality pixel-level annotations remains a critical challenge in the field of medical imaging. Semi-supervised learning (SSL) enhances the utilization of unlabeled data by facilitating knowledge transfer, significantly improving the performance of fully supervised models and emerging as a highly promising research direction in medical image analysis. Inspired by the ability of Vision Foundation Models (e.g., SAM-2) to provide rich prior knowledge, we propose SSS (Semi-Supervised SAM-2), a novel approach that leverages SAM-2's robust feature extraction capabilities to uncover latent knowledge in unlabeled medical images, thus effectively enhancing feature support for fully supervised medical image segmentation. Specifically, building upon the single-stream "weak-to-strong" consistency regularization framework, this paper introduces a Discriminative Feature Enhancement (DFE) mechanism to further explore the feature discrepancies introduced by various data augmentation strategies across multiple views. By leveraging feature similarity and dissimilarity across multi-scale augmentation techniques, the method reconstructs and models the features, thereby effectively optimizing the salient regions. Furthermore, a prompt generator is developed that integrates Physical Constraints with a Sliding Window (PCSW) mechanism to generate input prompts for unlabeled data, fulfilling SAM-2's requirement for additional prompts. Extensive experiments demonstrate the superiority of the proposed method for semi-supervised medical image segmentation on two multi-label datasets, i.e., ACDC and BHSD. Notably, SSS achieves an average Dice score of 53.15 on BHSD, surpassing the previous state-of-the-art method by +3.65 Dice. Code will be available at https://github.com/AIGeeksGroup/SSS.