Jun Hong

Jue Jiang, Jun Hong, Kathryn Tringale et al.

Method: ProRSeg was trained using 5-fold cross-validation with 110 T2-weighted MRI acquired at 5 treatment fractions from 10 different patients, taking care that same patient scans were not placed in training and testing folds. Segmentation accuracy was measured using Dice similarity coefficient (DSC) and Hausdorff distance at 95th percentile (HD95). Registration consistency was measured using coefficient of variation (CV) in displacement of OARs. Ablation tests and accuracy comparisons against multiple methods were done. Finally, applicability of ProRSeg to segment cone-beam CT (CBCT) scans was evaluated on 80 scans using 5-fold cross-validation. Results: ProRSeg processed 3D volumes (128 $\times$ 192 $\times$ 128) in 3 secs on a NVIDIA Tesla V100 GPU. It's segmentations were significantly more accurate ($p<0.001$) than compared methods, achieving a DSC of 0.94 $\pm$0.02 for liver, 0.88$\pm$0.04 for large bowel, 0.78$\pm$0.03 for small bowel and 0.82$\pm$0.04 for stomach-duodenum from MRI. ProRSeg achieved a DSC of 0.72$\pm$0.01 for small bowel and 0.76$\pm$0.03 for stomach-duodenum from CBCT. ProRSeg registrations resulted in the lowest CV in displacement (stomach-duodenum $CV_{x}$: 0.75\%, $CV_{y}$: 0.73\%, and $CV_{z}$: 0.81\%; small bowel $CV_{x}$: 0.80\%, $CV_{y}$: 0.80\%, and $CV_{z}$: 0.68\%; large bowel $CV_{x}$: 0.71\%, $CV_{y}$ : 0.81\%, and $CV_{z}$: 0.75\%). ProRSeg based dose accumulation accounting for intra-fraction (pre-treatment to post-treatment MRI scan) and inter-fraction motion showed that the organ dose constraints were violated in 4 patients for stomach-duodenum and for 3 patients for small bowel. Study limitations include lack of independent testing and ground truth phantom datasets to measure dose accumulation accuracy.

Jingyu Hu, Hongbo Bo, Jun Hong et al.

Graph Neural Networks (GNNs) often suffer from degree bias in node classification tasks, where prediction performance varies across nodes with different degrees. Several approaches, which adopt Graph Contrastive Learning (GCL), have been proposed to mitigate this bias. However, the limited number of positive pairs and the equal weighting of all positives and negatives in GCL still lead to low-degree nodes acquiring insufficient and noisy information. This paper proposes the Hardness Adaptive Reweighted (HAR) contrastive loss to mitigate degree bias. It adds more positive pairs by leveraging node labels and adaptively weights positive and negative pairs based on their learning hardness. In addition, we develop an experimental framework named SHARP to extend HAR to a broader range of scenarios. Both our theoretical analysis and experiments validate the effectiveness of SHARP. The experimental results across four datasets show that SHARP achieves better performance against baselines at both global and degree levels.

Oluwaseun Ajao, Deepak P, Jun Hong

The impact of social media and its growing association with the sharing of ideas and propagation of messages remains vital in everyday communication. Twitter is one effective platform for the dissemination of news and stories about recent events happening around the world. It has a continually growing database currently adopted by over 300 million users. In this paper we propose a novel grid-based approach employing supervised Multinomial Naive Bayes while extracting geographic entities from relevant user descriptions metadata which gives a spatial indication of the user location. To the best of our knowledge our approach is the first to make location inference from tweets using geo-enriched grid-based classification. Our approach performs better than existing baselines achieving more than 57% accuracy at city-level granularity. In addition we present a novel framework for content-based estimation of user locations by specifying levels of granularity required in pre-defined location grids.