Sara Khalid

CV
h-index24
3papers
21citations
Novelty32%
AI Score34

3 Papers

2.6LGAug 8, 2024
Advancing oncology with federated learning: transcending boundaries in breast, lung, and prostate cancer. A systematic review

Anshu Ankolekar, Sebastian Boie, Maryam Abdollahyan et al.

Federated Learning (FL) has emerged as a promising solution to address the limitations of centralised machine learning (ML) in oncology, particularly in overcoming privacy concerns and harnessing the power of diverse, multi-center data. This systematic review synthesises current knowledge on the state-of-the-art FL in oncology, focusing on breast, lung, and prostate cancer. Distinct from previous surveys, our comprehensive review critically evaluates the real-world implementation and impact of FL on cancer care, demonstrating its effectiveness in enhancing ML generalisability, performance and data privacy in clinical settings and data. We evaluated state-of-the-art advances in FL, demonstrating its growing adoption amid tightening data privacy regulations. FL outperformed centralised ML in 15 out of the 25 studies reviewed, spanning diverse ML models and clinical applications, and facilitating integration of multi-modal information for precision medicine. Despite the current challenges identified in reproducibility, standardisation and methodology across studies, the demonstrable benefits of FL in harnessing real-world data and addressing clinical needs highlight its significant potential for advancing cancer research. We propose that future research should focus on addressing these limitations and investigating further advanced FL methods, to fully harness data diversity and realise the transformative power of cutting-edge FL in cancer care.

8.7APApr 29
AlphaEarth Satellite Embeddings for Modelling Climate Sensitive Diseases Towards Global Health Resilience

Usman Nazir, I-Han Cheng, Sara Khalid

Malaria, childhood acute respiratory infection, and child undernutrition together account for over two million deaths annually in children under five, with the burden concentrated in low and middle-income countries where climate variability modulates transmission, exposure, and nutritional outcomes. Routine health surveillance in these settings remains sparse and reactive. Satellite-derived representations of the Earth's surface offer a scalable, low-cost complement to traditional covariates, yet their utility as predictors of population health outcomes is poorly characterised. We summarise findings from three studies evaluating AlphaEarth Foundations 64-dimensional satellite embeddings as predictors of population health outcomes, focusing on vulnerable populations. The studies span infectious disease (malaria, respiratory infection) and stunting. In each study, embeddings provide predictive value at sufficient spatial granularity: (i) malaria prediction across Nigeria shows consistent per-region R^2 gains; (ii) childhood acute respiratory infection prediction across 11 DHS countries increases pooled R^2 from 0.157 to 0.206 across three tree-based estimators; (iii) stunting prediction across 35 countries is neutral at country level due to collinearity with fixed effects. The stunting case is currently limited by lack of DHS cluster-level coordinates, which is the next key experiment.

2.8CVMar 21, 2023
Mitigating climate and health impact of small-scale kiln industry using multi-spectral classifier and deep learning

Usman Nazir, Murtaza Taj, Momin Uppal et al.

Industrial air pollution has a direct health impact and is a major contributor to climate change. Small scale industries particularly bull-trench brick kilns are one of the key sources of air pollution in South Asia often creating hazardous levels of smog that is injurious to human health. To mitigate the climate and health impact of the kiln industry, fine-grained kiln localization at different geographic locations is needed. Kiln localization using multi-spectral remote sensing data such as vegetation indices can result in a noisy estimates whereas relying solely on high-resolution imagery is infeasible due to cost and compute complexities. This paper proposes a fusion of spatio-temporal multi-spectral data with high-resolution imagery for detection of brick kilns within the "Brick-Kiln-Belt" of South Asia. We first perform classification using low-resolution spatio-temporal multi-spectral data from Sentinel-2 imagery by combining vegetation, burn, build up and moisture indices. Next, orientation aware object detector YOLOv3 (with theta value) is implemented for removal of false detections and fine-grained localization. Our proposed technique, when compared with other benchmarks, results in a 21 times improvement in speed with comparable or higher accuracy when tested over multiple countries.