Kuan-Cheng Chen

Kin Tung Michael Ho, Kuan-Cheng Chen, Lily Lee et al.

The escalating impacts of climate change and the increasing demand for sustainable development and natural resource management necessitate innovative technological solutions. Quantum computing (QC) has emerged as a promising tool with the potential to revolutionize these critical areas. This review explores the application of quantum machine learning and optimization techniques for climate change prediction and enhancing sustainable development. Traditional computational methods often fall short in handling the scale and complexity of climate models and natural resource management. Quantum advancements, however, offer significant improvements in computational efficiency and problem-solving capabilities. By synthesizing the latest research and developments, this paper highlights how QC and quantum machine learning can optimize multi-infrastructure systems towards climate neutrality. The paper also evaluates the performance of current quantum algorithms and hardware in practical applications and presents realistic cases, i.e., waste-to-energy in anaerobic digestion, disaster prevention in flooding prediction, and new material development for carbon capture. The integration of these quantum technologies promises to drive significant advancements in achieving climate resilience and sustainable development.

Kuan-Cheng Chen, Yi-Tien Li, Tai-Yu Li et al.

This paper introduces CompressedMediQ, a novel hybrid quantum-classical machine learning pipeline specifically developed to address the computational challenges associated with high-dimensional multi-class neuroimaging data analysis. Standard neuroimaging datasets, such as large-scale MRI data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and Neuroimaging in Frontotemporal Dementia (NIFD), present significant hurdles due to their vast size and complexity. CompressedMediQ integrates classical high-performance computing (HPC) nodes for advanced MRI pre-processing and Convolutional Neural Network (CNN)-PCA-based feature extraction and reduction, addressing the limited-qubit availability for quantum data encoding in the NISQ (Noisy Intermediate-Scale Quantum) era. This is followed by Quantum Support Vector Machine (QSVM) classification. By utilizing quantum kernel methods, the pipeline optimizes feature mapping and classification, enhancing data separability and outperforming traditional neuroimaging analysis techniques. Experimental results highlight the pipeline's superior accuracy in dementia staging, validating the practical use of quantum machine learning in clinical diagnostics. Despite the limitations of NISQ devices, this proof-of-concept demonstrates the transformative potential of quantum-enhanced learning, paving the way for scalable and precise diagnostic tools in healthcare and signal processing.

Kuan-Cheng Chen, Xiaotian Xu, Henry Makhanov et al.

In this study, we introduce an innovative Quantum-enhanced Support Vector Machine (QSVM) approach for stellar classification, leveraging the power of quantum computing and GPU acceleration. Our QSVM algorithm significantly surpasses traditional methods such as K-Nearest Neighbors (KNN) and Logistic Regression (LR), particularly in handling complex binary and multi-class scenarios within the Harvard stellar classification system. The integration of quantum principles notably enhances classification accuracy, while GPU acceleration using the cuQuantum SDK ensures computational efficiency and scalability for large datasets in quantum simulators. This synergy not only accelerates the processing process but also improves the accuracy of classifying diverse stellar types, setting a new benchmark in astronomical data analysis. Our findings underscore the transformative potential of quantum machine learning in astronomical research, marking a significant leap forward in both precision and processing speed for stellar classification. This advancement has broader implications for astrophysical and related scientific fields

Kuan-Cheng Chen, Wenxuan Ma, Xiaotian Xu

This paper presents a Consensus-based Distributed Quantum Kernel Learning (CDQKL) framework aimed at improving speech recognition through distributed quantum computing.CDQKL addresses the challenges of scalability and data privacy in centralized quantum kernel learning. It does this by distributing computational tasks across quantum terminals, which are connected through classical channels. This approach enables the exchange of model parameters without sharing local training data, thereby maintaining data privacy and enhancing computational efficiency. Experimental evaluations on benchmark speech emotion recognition datasets demonstrate that CDQKL achieves competitive classification accuracy and scalability compared to centralized and local quantum kernel learning models. The distributed nature of CDQKL offers advantages in privacy preservation and computational efficiency, making it suitable for data-sensitive fields such as telecommunications, automotive, and finance. The findings suggest that CDQKL can effectively leverage distributed quantum computing for large-scale machine-learning tasks.

Yu-Cheng Lin, Yu-Chao Hsu, I-Shan Tsai et al.

High-performance computing (HPC) is increasingly important for scalable quantum chemistry workflows that couple classical generative models, quantum circuit simulation, and selected configuration interaction postprocessing. We present the generative quantum-inspired Kolmogorov-Arnold eigensolver (GQKAE), a parameter-efficient extension of the generative quantum eigensolver (GQE) for quantum chemistry. GQKAE replaces the parameter-heavy feed-forward network components in GPT-style generative eigensolvers with hybrid quantum-inspired Kolmogorov-Arnold network modules, forming a compact HQKANsformer backbone. The method preserves autoregressive operator selection and the quantum-selected configuration interaction evaluation pipeline, while using single-qubit DatA Re-Uploading ActivatioN modules to provide expressive nonlinear mappings. Numerical benchmarks on H4, N2, LiH, C2H6, H2O, and the H2O dimer show that GQKAE achieves chemical accuracy comparable to the GPT-based GQE architecture, while reducing trainable parameters and memory by approximately 66% and improving wall-time performance. For strongly correlated systems such as N2 and LiH, GQKAE also improves convergence behavior and final energy errors. These results indicate that quantum-inspired Kolmogorov-Arnold networks can reduce classical-side overhead while preserving circuit-generation quality, offering a scalable route for HPC-quantum co-design on near-term quantum platforms.

Haomu Yuan, Hanqing Wu, Kuan-Cheng Chen et al.

Cardinality-constrained binary optimization is a fundamental computational primitive with broad applications in machine learning, finance, and scientific computing. In this work, we introduce a Grover-based quantum algorithm that exploits the structure of the fixed-cardinality feasible subspace under a natural promise on solution existence. For quadratic objectives, our approach achieves ${O}\left(\sqrt{\frac{\binom{n}{k}}{M}}\right)$ Grover rotations for any fixed cardinality $k$ and degeneracy of the optima $M$, yielding an exponential reduction in the number of Grover iterations compared with unstructured search over $\{0,1\}^n$. Building on this result, we develop a hybrid classical--quantum framework based on the alternating direction method of multipliers (ADMM) algorithm. The proposed framework is guaranteed to output an $ε$-approximate solution with a consistency tolerance $ε+ δ$ using at most $ {O}\left(\sqrt{\binom{n}{k}}\frac{n^{6}k^{3/2} }{ \sqrt{M}ε^2 δ}\right)$ queries to a quadratic oracle, together with ${O}\left(\frac{n^{6}k^{3/2}}{ε^2δ}\right)$ classical overhead. Overall, our method suggests a practical use of quantum resources and demonstrates an exponential improvements over existing Grover-based approaches in certain parameter regimes, thereby paving the way toward quantum advantage in constrained binary optimization.

Kuan-Cheng Chen, Samuel Yen-Chi Chen, Chen-Yu Liu et al.

The rapid growth of industrial Internet of Things (IIoT) systems has created new challenges for anomaly detection in high-dimensional, multivariate time-series, where privacy, scalability, and communication efficiency are critical. Classical federated learning approaches mitigate privacy concerns by enabling decentralized training, but they often struggle with highly non-linear decision boundaries and imbalanced anomaly distributions. To address this gap, we propose a Federated Quantum Kernel Learning (FQKL) framework that integrates quantum feature maps with federated aggregation to enable distributed, privacy-preserving anomaly detection across heterogeneous IoT networks. In our design, quantum edge nodes locally compute compressed kernel statistics using parameterized quantum circuits and share only these summaries with a central server, which constructs a global Gram matrix and trains a decision function (e.g., Fed-QSVM). Experimental results on synthetic IIoT benchmarks demonstrate that FQKL achieves superior generalization in capturing complex temporal correlations compared to classical federated baselines, while significantly reducing communication overhead. This work highlights the promise of quantum kernels in federated settings, advancing the path toward scalable, robust, and quantum-enhanced intelligence for next-generation IoT infrastructures.

Kuan-Cheng Chen, Shang Yu, Chen-Yu Liu et al.

Photonic quantum processors naturally produce intrinsically stochastic measurement outcomes, offering a hardware-native source of structured randomness that can be exploited during machine-learning training. Here we introduce Photonic Quantum-Enhanced Knowledge Distillation (PQKD), a hybrid quantum photonic--classical framework in which a programmable photonic circuit generates a compact conditioning signal that constrains and guides a parameter-efficient student network during distillation from a high-capacity teacher. PQKD replaces fully trainable convolutional kernels with dictionary convolutions: each layer learns only a small set of shared spatial basis filters, while sample-dependent channel-mixing weights are derived from shot-limited photonic features and mapped through a fixed linear transform. Training alternates between standard gradient-based optimisation of the student and sampling-robust, gradient-free updates of photonic parameters, avoiding differentiation through photonic hardware. Across MNIST, Fashion-MNIST and CIFAR-10, PQKD traces a controllable compression--accuracy frontier, remaining close to teacher performance on simpler benchmarks under aggressive convolutional compression. Performance degrades predictably with finite sampling, consistent with shot-noise scaling, and exponential moving-average feature smoothing suppresses high-frequency shot-noise fluctuations, extending the practical operating regime at moderate shot budgets.

Kuo-Chung Peng, Samuel Yen-Chi Chen, Jiun-Cheng Jiang et al.

Fast Weight Programmers (FWPs) encode temporal dependencies through dynamically updated parameters rather than recurrent hidden states. Quantum FWPs (QFWPs) extend this idea with variational quantum circuits (VQCs), but existing implementations rely on multi-qubit architectures that are difficult to scale on noisy intermediate-scale quantum (NISQ) devices and expensive to simulate classically. We propose gated QKAN-FWP, a fast-weight framework that integrates FWP with Quantum-inspired Kolmogorov-Arnold Network (QKAN) using single-qubit data re-uploading circuits as learnable nonlinear activation, known as DatA Re-Uploading ActivatioN (DARUAN). We further introduce a scalar-gated fast-weight update rule that stabilizes parameter evolution, supported by a theoretical analysis of its adaptive memory kernel, geometric boundedness, and parallelizable gradient paths. We evaluate the framework across time-series benchmarks, MiniGrid reinforcement learning, and highlight real-world solar cycle forecasting as our main practical result. In the long-horizon setting with 528-month input window and 132-month forecast horizon, our 12.5k-parameter model achieves lower scaled Mean Square Error (MSE), peak amplitude error, and peak timing error than a suite of classical recurrent baselines with up to 13x more parameters, including Long Short-Term Memory (LSTM) networks (25.9k-89.1k parameters), WaveNet-LSTM (167k), Vanilla recurrent neural network (11.5k), and a Modified Echo State Network (132k). To validate NISQ compatibility, we further deploy the trained fast programmer on IonQ and IBM Quantum processors, recovering forecasting accuracy within 0.1% relative MSE of the noiseless simulator at 1024 shots. These results position gated QKAN-FWP as a scalable, parameter-efficient, and NISQ-compatible approach to quantum-inspired sequence modeling.

Kuan-Cheng Chen, Samuel Yen-Chi Chen, Chen-Yu Liu et al.

In this paper, we introduce Quantum-Train-Based Distributed Multi-Agent Reinforcement Learning (Dist-QTRL), a novel approach to addressing the scalability challenges of traditional Reinforcement Learning (RL) by integrating quantum computing principles. Quantum-Train Reinforcement Learning (QTRL) leverages parameterized quantum circuits to efficiently generate neural network parameters, achieving a \(poly(\log(N))\) reduction in the dimensionality of trainable parameters while harnessing quantum entanglement for superior data representation. The framework is designed for distributed multi-agent environments, where multiple agents, modeled as Quantum Processing Units (QPUs), operate in parallel, enabling faster convergence and enhanced scalability. Additionally, the Dist-QTRL framework can be extended to high-performance computing (HPC) environments by utilizing distributed quantum training for parameter reduction in classical neural networks, followed by inference using classical CPUs or GPUs. This hybrid quantum-HPC approach allows for further optimization in real-world applications. In this paper, we provide a mathematical formulation of the Dist-QTRL framework and explore its convergence properties, supported by empirical results demonstrating performance improvements over centric QTRL models. The results highlight the potential of quantum-enhanced RL in tackling complex, high-dimensional tasks, particularly in distributed computing settings, where our framework achieves significant speedups through parallelization without compromising model accuracy. This work paves the way for scalable, quantum-enhanced RL systems in practical applications, leveraging both quantum and classical computational resources.

Yu-Chao Hsu, Tai-Yu Li, Kuan-Cheng Chen

The integration of quantum computing into classical machine learning architectures has emerged as a promising approach to enhance model efficiency and computational capacity. In this work, we introduce the Quantum Kernel-Based Long Short-Term Memory (QK-LSTM) network, which utilizes quantum kernel functions within the classical LSTM framework to capture complex, non-linear patterns in sequential data. By embedding input data into a high-dimensional quantum feature space, the QK-LSTM model reduces the reliance on large parameter sets, achieving effective compression while maintaining accuracy in sequence modeling tasks. This quantum-enhanced architecture demonstrates efficient convergence, robust loss minimization, and model compactness, making it suitable for deployment in edge computing environments and resource-limited quantum devices (especially in the NISQ era). Benchmark comparisons reveal that QK-LSTM achieves performance on par with classical LSTM models, yet with fewer parameters, underscoring its potential to advance quantum machine learning applications in natural language processing and other domains requiring efficient temporal data processing.

Chu-Hsuan Abraham Lin, Chen-Yu Liu, Samuel Yen-Chi Chen et al.

The rise of deepfake technologies has posed significant challenges to privacy, security, and information integrity, particularly in audio and multimedia content. This paper introduces a Quantum-Trained Convolutional Neural Network (QT-CNN) framework designed to enhance the detection of deepfake audio, leveraging the computational power of quantum machine learning (QML). The QT-CNN employs a hybrid quantum-classical approach, integrating Quantum Neural Networks (QNNs) with classical neural architectures to optimize training efficiency while reducing the number of trainable parameters. Our method incorporates a novel quantum-to-classical parameter mapping that effectively utilizes quantum states to enhance the expressive power of the model, achieving up to 70% parameter reduction compared to classical models without compromising accuracy. Data pre-processing involved extracting essential audio features, label encoding, feature scaling, and constructing sequential datasets for robust model evaluation. Experimental results demonstrate that the QT-CNN achieves comparable performance to traditional CNNs, maintaining high accuracy during training and testing phases across varying configurations of QNN blocks. The QT framework's ability to reduce computational overhead while maintaining performance underscores its potential for real-world applications in deepfake detection and other resource-constrained scenarios. This work highlights the practical benefits of integrating quantum computing into artificial intelligence, offering a scalable and efficient approach to advancing deepfake detection technologies.

Yu-Chao Hsu, Nan-Yow Chen, Tai-Yu Li et al.

We present the Quantum Kernel-Based Long short-memory (QK-LSTM) network, which integrates quantum kernel methods into classical LSTM architectures to enhance predictive accuracy and computational efficiency in climate time-series forecasting tasks, such as Air Quality Index (AQI) prediction. By embedding classical inputs into high-dimensional quantum feature spaces, QK-LSTM captures intricate nonlinear dependencies and temporal dynamics with fewer trainable parameters. Leveraging quantum kernel methods allows for efficient computation of inner products in quantum spaces, addressing the computational challenges faced by classical models and variational quantum circuit-based models. Designed for the Noisy Intermediate-Scale Quantum (NISQ) era, QK-LSTM supports scalable hybrid quantum-classical implementations. Experimental results demonstrate that QK-LSTM outperforms classical LSTM networks in AQI forecasting, showcasing its potential for environmental monitoring and resource-constrained scenarios, while highlighting the broader applicability of quantum-enhanced machine learning frameworks in tackling large-scale, high-dimensional climate datasets.

Kuan-Cheng Chen, Xiaoren Li, Xiaotian Xu et al.

Achieving high-performance computation on quantum systems presents a formidable challenge that necessitates bridging the capabilities between quantum hardware and classical computing resources. This study introduces an innovative distribution-aware Quantum-Classical-Quantum (QCQ) architecture, which integrates cutting-edge quantum software framework works with high-performance classical computing resources to address challenges in quantum simulation for materials and condensed matter physics. At the heart of this architecture is the seamless integration of VQE algorithms running on QPUs for efficient quantum state preparation, Tensor Network states, and QCNNs for classifying quantum states on classical hardware. For benchmarking quantum simulators, the QCQ architecture utilizes the cuQuantum SDK to leverage multi-GPU acceleration, integrated with PennyLane's Lightning plugin, demonstrating up to tenfold increases in computational speed for complex phase transition classification tasks compared to traditional CPU-based methods. This significant acceleration enables models such as the transverse field Ising and XXZ systems to accurately predict phase transitions with a 99.5% accuracy. The architecture's ability to distribute computation between QPUs and classical resources addresses critical bottlenecks in Quantum-HPC, paving the way for scalable quantum simulation. The QCQ framework embodies a synergistic combination of quantum algorithms, machine learning, and Quantum-HPC capabilities, enhancing its potential to provide transformative insights into the behavior of quantum systems across different scales. As quantum hardware continues to improve, this hybrid distribution-aware framework will play a crucial role in realizing the full potential of quantum computing by seamlessly integrating distributed quantum resources with the state-of-the-art classical computing infrastructure.

Kuan-Cheng Chen, Samuel Yen-Chi Chen, Chen-Yu Liu et al.

In this work, we introduce a Distributed Quantum Long Short-Term Memory (QLSTM) framework that leverages modular quantum computing to address scalability challenges on Noisy Intermediate-Scale Quantum (NISQ) devices. By embedding variational quantum circuits into LSTM cells, the QLSTM captures long-range temporal dependencies, while a distributed architecture partitions the underlying Variational Quantum Circuits (VQCs) into smaller, manageable subcircuits that can be executed on a network of quantum processing units. We assess the proposed framework using nontrivial benchmark problems such as damped harmonic oscillators and Nonlinear Autoregressive Moving Average sequences. Our results demonstrate that the distributed QLSTM achieves stable convergence and improved training dynamics compared to classical approaches. This work underscores the potential of modular, distributed quantum computing architectures for large-scale sequence modelling, providing a foundation for the future integration of hybrid quantum-classical solutions into advanced Quantum High-performance computing (HPC) ecosystems.

Samuel Yen-Chi Chen, Chen-Yu Liu, Kuan-Cheng Chen et al.

The rapid advancements in quantum computing (QC) and machine learning (ML) have led to the emergence of quantum machine learning (QML), which integrates the strengths of both fields. Among QML approaches, variational quantum circuits (VQCs), also known as quantum neural networks (QNNs), have shown promise both empirically and theoretically. However, their broader adoption is hindered by reliance on quantum hardware during inference. Hardware imperfections and limited access to quantum devices pose practical challenges. To address this, the Quantum-Train (QT) framework leverages the exponential scaling of quantum amplitudes to generate classical neural network parameters, enabling inference without quantum hardware and achieving significant parameter compression. Yet, designing effective quantum circuit architectures for such quantum-enhanced neural programmers remains non-trivial and often requires expertise in quantum information science. In this paper, we propose an automated solution using differentiable optimization. Our method jointly optimizes both conventional circuit parameters and architectural parameters in an end-to-end manner via automatic differentiation. We evaluate the proposed framework on classification, time-series prediction, and reinforcement learning tasks. Simulation results show that our method matches or outperforms manually designed QNN architectures. This work offers a scalable and automated pathway for designing QNNs that can generate classical neural network parameters across diverse applications.

Chen-Yu Liu, Kuan-Cheng Chen, Yi-Chien Chen et al.

Typhoon trajectory forecasting is essential for disaster preparedness but remains computationally demanding due to the complexity of atmospheric dynamics and the resource requirements of deep learning models. Quantum-Train (QT), a hybrid quantum-classical framework that leverages quantum neural networks (QNNs) to generate trainable parameters exclusively during training, eliminating the need for quantum hardware at inference time. Building on QT's success across multiple domains, including image classification, reinforcement learning, flood prediction, and large language model (LLM) fine-tuning, we introduce Quantum Parameter Adaptation (QPA) for efficient typhoon forecasting model learning. Integrated with an Attention-based Multi-ConvGRU model, QPA enables parameter-efficient training while maintaining predictive accuracy. This work represents the first application of quantum machine learning (QML) to large-scale typhoon trajectory prediction, offering a scalable and energy-efficient approach to climate modeling. Our results demonstrate that QPA significantly reduces the number of trainable parameters while preserving performance, making high-performance forecasting more accessible and sustainable through hybrid quantum-classical learning.

Kuan-Cheng Chen, Chen-Yu Liu, Yu Shang et al.

We introduce a distributed quantum-classical framework that synergizes photonic quantum neural networks (QNNs) with matrix-product-state (MPS) mapping to achieve parameter-efficient training of classical neural networks. By leveraging universal linear-optical decompositions of $M$-mode interferometers and photon-counting measurement statistics, our architecture generates neural parameters through a hybrid quantum-classical workflow: photonic QNNs with $M(M+1)/2$ trainable parameters produce high-dimensional probability distributions that are mapped to classical network weights via an MPS model with bond dimension $χ$. Empirical validation on MNIST classification demonstrates that photonic QT achieves an accuracy of $95.50\% \pm 0.84\%$ using 3,292 parameters ($χ= 10$), compared to $96.89\% \pm 0.31\%$ for classical baselines with 6,690 parameters. Moreover, a ten-fold compression ratio is achieved at $χ= 4$, with a relative accuracy loss of less than $3\%$. The framework outperforms classical compression techniques (weight sharing/pruning) by 6--12\% absolute accuracy while eliminating quantum hardware requirements during inference through classical deployment of compressed parameters. Simulations incorporating realistic photonic noise demonstrate the framework's robustness to near-term hardware imperfections. Ablation studies confirm quantum necessity: replacing photonic QNNs with random inputs collapses accuracy to chance level ($10.0\% \pm 0.5\%$). Photonic quantum computing's room-temperature operation, inherent scalability through spatial-mode multiplexing, and HPC-integrated architecture establish a practical pathway for distributed quantum machine learning, combining the expressivity of photonic Hilbert spaces with the deployability of classical neural networks.

Kuan-Cheng Chen, Hiromichi Matsuyama, Wei-Hao Huang

Quantum Approximate Optimization Algorithms (QAOA) promise efficient solutions to classically intractable combinatorial optimization problems by harnessing shallow-depth quantum circuits. Yet, their performance and scalability often hinge on effective parameter optimization, which remains nontrivial due to rugged energy landscapes and hardware noise. In this work, we introduce a quantum meta-learning framework that combines quantum neural networks, specifically Quantum Long Short-Term Memory (QLSTM) architectures, with QAOA. By training the QLSTM optimizer on smaller graph instances, our approach rapidly generalizes to larger, more complex problems, substantially reducing the number of iterations required for convergence. Through comprehensive benchmarks on Max-Cut and Sherrington-Kirkpatrick model instances, we demonstrate that QLSTM-based optimizers converge faster and achieve higher approximation ratios compared to classical baselines, thereby offering a robust pathway toward scalable quantum optimization in the NISQ era.

Kuan-Cheng Chen, Samuel Yen-Chi Chen, Tai-Yue Li et al.

Intrusion detection in unmanned-aerial-vehicle (UAV) swarms is complicated by high mobility, non-stationary traffic, and severe class imbalance. Leveraging a 120 k-flow simulation corpus that covers five attack types, we benchmark three quantum-machine-learning (QML) approaches - quantum kernels, variational quantum neural networks (QNNs), and hybrid quantum-trained neural networks (QT-NNs) - against strong classical baselines. All models consume an 8-feature flow representation and are evaluated under identical preprocessing, balancing, and noise-model assumptions. We analyse the influence of encoding strategy, circuit depth, qubit count, and shot noise, reporting accuracy, macro-F1, ROC-AUC, Matthews correlation, and quantum-resource footprints. Results reveal clear trade-offs: quantum kernels and QT-NNs excel in low-data, nonlinear regimes, while deeper QNNs suffer from trainability issues, and CNNs dominate when abundant data offset their larger parameter count. The complete codebase and dataset partitions are publicly released to enable reproducible QML research in network security.

Kuan-Cheng Chen, Huan-Hsin Tseng, Samuel Yen-Chi Chen et al.

We propose SUN-VQC, a variational-circuit architecture whose elementary layers are single exponentials of a symmetry-restricted Lie subgroup, $\mathrm{SU}(2^{k}) \subset \mathrm{SU}(2^{n})$ with $k \ll n$. Confining the evolution to this compact subspace reduces the dynamical Lie-algebra dimension from $\mathcal{O}(4^{n})$ to $\mathcal{O}(4^{k})$, ensuring only polynomial suppression of gradient variance and circumventing barren plateaus that plague hardware-efficient ansätze. Exact, hardware-compatible gradients are obtained using a generalized parameter-shift rule, avoiding ancillary qubits and finite-difference bias. Numerical experiments on quantum auto-encoding and classification show that SUN-VQCs sustain order-of-magnitude larger gradient signals, converge 2--3$\times$ faster, and reach higher final fidelities than depth-matched Pauli-rotation or hardware-efficient circuits. These results demonstrate that Lie-subalgebra engineering provides a principled, scalable route to barren-plateau-resilient VQAs compatible with near-term quantum processors.

Chen-Yu Liu, Leonardo Placidi, Kuan-Cheng Chen et al.

Quantum machine learning (QML) models conventionally rely on repeated measurements (shots) of observables to obtain reliable predictions. This dependence on large shot budgets leads to high inference cost and time overhead, which is particularly problematic as quantum hardware access is typically priced proportionally to the number of shots. In this work we propose You Only Measure Once (Yomo), a simple yet effective design that achieves accurate inference with dramatically fewer measurements, down to the single-shot regime. Yomo replaces Pauli expectation-value outputs with a probability aggregation mechanism and introduces loss functions that encourage sharp predictions. Our theoretical analysis shows that Yomo avoids the shot-scaling limitations inherent to expectation-based models, and our experiments on MNIST and CIFAR-10 confirm that Yomo consistently outperforms baselines across different shot budgets and under simulations with depolarizing channels. By enabling accurate single-shot inference, Yomo substantially reduces the financial and computational costs of deploying QML, thereby lowering the barrier to practical adoption of QML.