Wei Chen

Yuanlei Zheng, Pei Fu, Hang Li et al.

Multi-page Document Visual Question Answering requires reasoning over semantics, layouts, and visual elements in long, visually dense documents. Existing OCR-free methods face a trade-off between capacity and precision: end-to-end models scale poorly with document length, while visual retrieval-based pipelines are brittle and passive. We propose Doc-$V^*$, an \textbf{OCR-free agentic} framework that casts multi-page DocVQA as sequential evidence aggregation. Doc-$V^*$ begins with a thumbnail overview, then actively navigates via semantic retrieval and targeted page fetching, and aggregates evidence in a structured working memory for grounded reasoning. Trained by imitation learning from expert trajectories and further optimized with Group Relative Policy Optimization, Doc-$V^*$ balances answer accuracy with evidence-seeking efficiency. Across five benchmarks, Doc-$V^*$ outperforms open-source baselines and approaches proprietary models, improving out-of-domain performance by up to \textbf{47.9\%} over RAG baseline. Other results reveal effective evidence aggregation with selective attention, not increased input pages.

Yingyong Hou, Xinyuan Lao, Huimei Wang et al.

Background: Agent skills are increasingly deployed as modular, reusable capability units in AI agent systems. Medical research agent skills require safeguards beyond general-purpose evaluation, including scientific integrity, methodological validity, reproducibility, and boundary safety. This study developed and preliminarily evaluated a domain-specific audit framework for medical research agent skills, with a focus on reliability against expert review. Methods: We developed MedSkillAudit (skill-auditor@1.0), a layered framework assessing skill release readiness before deployment. We evaluated 75 skills across five medical research categories (15 per category). Two experts independently assigned a quality score (0-100), an ordinal release disposition (Production Ready / Limited Release / Beta Only / Reject), and a high-risk failure flag. System-expert agreement was quantified using ICC(2,1) and linearly weighted Cohen's kappa, benchmarked against the human inter-rater baseline. Results: The mean consensus quality score was 72.4 (SD = 13.0); 57.3% of skills fell below the Limited Release threshold. MedSkillAudit achieved ICC(2,1) = 0.449 (95% CI: 0.250-0.610), exceeding the human inter-rater ICC of 0.300. System-consensus score divergence (SD = 9.5) was smaller than inter-expert divergence (SD = 12.4), with no directional bias (Wilcoxon p = 0.613). Protocol Design showed the strongest category-level agreement (ICC = 0.551); Academic Writing showed a negative ICC (-0.567), reflecting a structural rubric-expert mismatch. Conclusions: Domain-specific pre-deployment audit may provide a practical foundation for governing medical research agent skills, complementing general-purpose quality checks with structured audit workflows tailored to scientific use cases.

Zhijie Bao, Fangke Chen, Licheng Bao et al.

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that report single or coarse-grained metrics are lack the granularity required for specialized clinical support and fail to assess the reliability of reasoning mechanisms. To address this, we propose a paradigm shift toward multidimensional, fine-grained and in-depth evaluation. Based on a two-stage systematic construction pipeline designed for this paradigm, we instantiate it with MedRCube. We benchmark 33 MLLMs, \textit{Lingshu-32B} achieve top-tier performance. Crucially, MedRCube exposes a series of pronounced insights inaccessible under prior evaluation settings. Furthermore, we introduce a credibility evaluation subset to quantify reasoning credibility, uncover a highly significant positive association between shortcut behavior and diagnostic task performance, raising concerns for clinically trustworthy deployment. The resources of this work can be found at https://github.com/F1mc/MedRCube.

Fengxian Dong, Zhi Zheng, Xiao Han et al.

Automated feature generation extracts informative features from raw tabular data without manual intervention and is crucial for accurate, generalizable machine learning. Traditional methods rely on predefined operator libraries and cannot leverage task semantics, limiting their ability to produce diverse, high-value features for complex tasks. Recent Large Language Model (LLM)-based approaches introduce richer semantic signals, but still suffer from a restricted feature space due to fixed generation patterns and from the absence of feedback from the learning objective. To address these challenges, we propose a Memory-Augmented LLM-based Multi-Agent System (\textbf{MALMAS}) for automated feature generation. MALMAS decomposes the generation process into agents with distinct responsibilities, and a Router Agent activates an appropriate subset of agents per iteration, further broadening exploration of the feature space. We further integrate a memory module comprising procedural memory, feedback memory, and conceptual memory, enabling iterative refinement that adaptively guides subsequent feature generation and improves feature quality and diversity. Extensive experiments on multiple public datasets against state-of-the-art baselines demonstrate the effectiveness of our approach. The code is available at https://github.com/fxdong24/MALMAS

Baran Atalar, Xutong Liu, Jinhang Zuo et al.

As Large Language Models (LLMs) become increasingly popular, caching responses so that they can be reused by users with semantically similar queries has become a vital strategy for reducing inference costs and latency. Existing caching frameworks have proposed to decide which query responses to cache by assuming a finite, known universe of discrete queries and learning their serving costs and arrival probabilities. As LLMs' pool of users and queries expands, however, such an assumption becomes increasingly untenable: real-world LLM queries reside in an infinite, continuous embedding space. In this paper, we establish the first rigorous theoretical framework for semantic LLM response caching in continuous query space under uncertainty. To bridge the gap between discrete optimization and continuous representation spaces, we introduce dynamic $ε$-net discretization coupled with Kernel Ridge Regression. This design enables the system to formally quantify estimation uncertainty and generalize partial feedback on LLM query costs across continuous semantic query neighborhoods. We develop both offline learning and online adaptive algorithms optimized to reduce switching costs incurred by changing the cached responses. We prove that our online algorithm achieves a sublinear regret bound against an optimal continuous oracle, which reduces to existing bounds for discrete query models. Extensive empirical evaluations demonstrate that our framework approximates the continuous optimal cache well while also reducing computational and switching overhead compared to existing methods.

Yu Zhang, Xing Shen, Kemeng Huang et al.

Incremental Potential Contact (IPC) guarantees intersection-free simulation but suffers from high computational costs due to the expensive Hessian assembly and linear solves required by Newton's method. While Preconditioned Nonlinear Conjugate Gradient (PNCG) avoids Hessian assembly, it has historically struggled with poor convergence in stiff, contact-rich scenarios due to the lack of effective preconditioners; simple Jacobi preconditioners fail to capture the global coupling, while advanced hierarchy-based preconditioners like Multilevel Additive Schwarz (MAS) are computationally prohibitive to rebuild at every nonlinear iteration. We present MAS-PNCG, a method that unlocks the power of hierarchical preconditioning for nonlinear optimization. Our key technical innovation is a Sparse-Input Woodbury update algorithm that incrementally adapts the fine-level MAS components to rapidly evolving contact sets. This bypasses the need for full preconditioner rebuilds, reducing maintenance cost to near-zero while capturing the complex spectral properties of the contact system. Furthermore, we replace heuristic PNCG search directions with a Hessian-aware 2D subspace minimization that optimally combines the preconditioned gradient and previous direction. We also apply a fast per-subdomain conservative CCD method that ensures penetration-free trajectories while avoiding overly restrictive global step sizes. Experiments demonstrate that our MAS-PNCG outperforms state-of-the-art Newton-PCG solvers, GIPC and StiffGIPC, both preconditioned with MAS up to 5.66$\times$ and 2.07$\times$ respectively.

Yahao Pang, Xingyuan Wu, Xiaojin Zhang et al.

Significant advancements have been made by Large Language Models (LLMs) in the domains of natural language understanding and automated content creation. However, they still face persistent problems, including substantial computational costs and inadequate availability of training data. The combination of Federated Learning (FL) and LLMs (federated LLMs) offers a solution by leveraging distributed data while protecting privacy, which positions it as an ideal choice for sensitive domains. However, Federated LLMs still suffer from robustness challenges, including data heterogeneity, malicious clients, and adversarial attacks, which greatly hinder their applications. We first introduce the robustness problems in federated LLMs, to address these challenges, we propose FedEAT (Federated Embedding space Adversarial Training), a novel framework that applies adversarial training in the embedding space of client LLM and employs a robust aggregation approach, specifically geometric median aggregation, to enhance the robustness of Federated LLMs. Our experiments demonstrate that FedEAT effectively improves the robustness of Federated LLMs with minimal performance loss.

Siyu He, Yin Li, Yu Feng et al.

Matter evolved under influence of gravity from minuscule density fluctuations. Non-perturbative structure formed hierarchically over all scales, and developed non-Gaussian features in the Universe, known as the Cosmic Web. To fully understand the structure formation of the Universe is one of the holy grails of modern astrophysics. Astrophysicists survey large volumes of the Universe and employ a large ensemble of computer simulations to compare with the observed data in order to extract the full information of our own Universe. However, to evolve trillions of galaxies over billions of years even with the simplest physics is a daunting task. We build a deep neural network, the Deep Density Displacement Model (hereafter D$^3$M), to predict the non-linear structure formation of the Universe from simple linear perturbation theory. Our extensive analysis, demonstrates that D$^3$M outperforms the second order perturbation theory (hereafter 2LPT), the commonly used fast approximate simulation method, in point-wise comparison, 2-point correlation, and 3-point correlation. We also show that D$^3$M is able to accurately extrapolate far beyond its training data, and predict structure formation for significantly different cosmological parameters. Our study proves, for the first time, that deep learning is a practical and accurate alternative to approximate simulations of the gravitational structure formation of the Universe.