Dayu Tan

Rui Hao, Dayu Tan, Qiankun Li et al.

Accurate segmentation of organs-at-risk (OARs) is vital for safe and precise radiotherapy and surgery. Most existing studies segment only a limited set of organs or regions, lacking a systematic treatment of OARs segmentation. We present a Multi-scale Cascaded Fusion Network (MCFNet) that aggregates features across multiple scales and resolutions. MCFNet consists of a Sharp Extraction Backbone for the downsampling path and a Flexible Connection Backbone for skip-connection fusion, strengthening representation learning in both stages. This design improves boundary localization and preserves fine structures while maintaining computational efficiency, enabling reliable performance even on low-resolution inputs. Experiments on an NVIDIA A6000 GPU using 36,131 image-mask pairs from 671 patients across 10 datasets show consistent robustness and strong cross-dataset generalization. An adaptive loss-aggregation strategy further stabilizes optimization and yields additional gains in accuracy and training efficiency. Through extensive validation, MCFNet outperforms existing methods, excelling in organ segmentation and providing reliable image-guided support for computer-aided diagnosis. Our solution aims to improve the precision and safety of radiotherapy and surgery while supporting personalized treatment, advancing modern medical technology. The code has been made available on GitHub: https://github.com/Henry991115/MCFNet.

Dayu Tan, Cheng Kong, Yansen Su et al.

In the field of multi-organ medical image segmentation, recent methods frequently employ Transformers to capture long-range dependencies from image features. However, these methods overlook the high computational cost of Transformers and their deficiencies in extracting local detailed information. To address high computational costs and inadequate local detail information, we reassess the design of feature extraction modules and propose a new deep-learning network called LamFormer for fine-grained segmentation tasks across multiple organs. LamFormer is a novel U-shaped network that employs Linear Attention Mamba (LAM) in an enhanced pyramid encoder to capture multi-scale long-range dependencies. We construct the Parallel Hierarchical Feature Aggregation (PHFA) module to aggregate features from different layers of the encoder, narrowing the semantic gap among features while filtering information. Finally, we design the Reduced Transformer (RT), which utilizes a distinct computational approach to globally model up-sampled features. RRT enhances the extraction of detailed local information and improves the network's capability to capture long-range dependencies. LamFormer outperforms existing segmentation methods on seven complex and diverse datasets, demonstrating exceptional performance. Moreover, the proposed network achieves a balance between model performance and model complexity.

Dayu Tan, Zheng Huang, Xin Peng et al.

Cluster assignment of large and complex images is a crucial but challenging task in pattern recognition and computer vision. In this study, we explore the possibility of employing fuzzy clustering in a deep neural network framework. Thus, we present a novel evolutionary unsupervised learning representation model with iterative optimization. It implements the deep adaptive fuzzy clustering (DAFC) strategy that learns a convolutional neural network classifier from given only unlabeled data samples. DAFC consists of a deep feature quality-verifying model and a fuzzy clustering model, where deep feature representation learning loss function and embedded fuzzy clustering with the weighted adaptive entropy is implemented. We joint fuzzy clustering to the deep reconstruction model, in which fuzzy membership is utilized to represent a clear structure of deep cluster assignments and jointly optimize for the deep representation learning and clustering. Also, the joint model evaluates current clustering performance by inspecting whether the re-sampled data from estimated bottleneck space have consistent clustering properties to progressively improve the deep clustering model. Comprehensive experiments on a variety of datasets show that the proposed method obtains a substantially better performance for both reconstruction and clustering quality when compared to the other state-of-the-art deep clustering methods, as demonstrated with the in-depth analysis in the extensive experiments.