Renzhen Wang

Quanziang Wang, Renzhen Wang, Yichen Wu et al. · harvard

Online continual learning (CL) aims to learn new knowledge and consolidate previously learned knowledge from non-stationary data streams. Due to the time-varying training setting, the model learned from a changing distribution easily forgets the previously learned knowledge and biases toward the newly received task. To address this problem, we propose a Continual Bias Adaptor (CBA) module to augment the classifier network to adapt to catastrophic distribution change during training, such that the classifier network is able to learn a stable consolidation of previously learned tasks. In the testing stage, CBA can be removed which introduces no additional computation cost and memory overhead. We theoretically reveal the reason why the proposed method can effectively alleviate catastrophic distribution shifts, and empirically demonstrate its effectiveness through extensive experiments based on four rehearsal-based baselines and three public continual learning benchmarks.

Renzhen Wang, Xixi Jia, Quanziang Wang et al. · harvard

Pseudo-labeling has proven to be a promising semi-supervised learning (SSL) paradigm. Existing pseudo-labeling methods commonly assume that the class distributions of training data are balanced. However, such an assumption is far from realistic scenarios and thus severely limits the performance of current pseudo-labeling methods under the context of class-imbalance. To alleviate this problem, we design a bias adaptive classifier that targets the imbalanced SSL setups. The core idea is to automatically assimilate the training bias caused by class imbalance via the bias adaptive classifier, which is composed of a novel bias attractor and the original linear classifier. The bias attractor is designed as a light-weight residual network and optimized through a bi-level learning framework. Such a learning strategy enables the bias adaptive classifier to fit imbalanced training data, while the linear classifier can provide unbiased label prediction for each class. We conduct extensive experiments under various imbalanced semi-supervised setups, and the results demonstrate that our method can be applied to different pseudo-labeling models and is superior to current state-of-the-art methods.

Quanziang Wang, Renzhen Wang, Yichen Wu et al. · harvard

In online continual learning (CL), models trained on changing distributions easily forget previously learned knowledge and bias toward newly received tasks. To address this issue, we present Continual Bias Adaptor (CBA), a bi-level framework that augments the classification network to adapt to catastrophic distribution shifts during training, enabling the network to achieve a stable consolidation of all seen tasks. However, the CBA module adjusts distribution shifts in a class-specific manner, exacerbating the stability gap issue and, to some extent, fails to meet the need for continual testing in online CL. To mitigate this challenge, we further propose a novel class-agnostic CBA module that separately aggregates the posterior probabilities of classes from new and old tasks, and applies a stable adjustment to the resulting posterior probabilities. We combine the two kinds of CBA modules into a unified Dual-CBA module, which thus is capable of adapting to catastrophic distribution shifts and simultaneously meets the real-time testing requirements of online CL. Besides, we propose Incremental Batch Normalization (IBN), a tailored BN module to re-estimate its population statistics for alleviating the feature bias arising from the inner loop optimization problem of our bi-level framework. To validate the effectiveness of the proposed method, we theoretically provide some insights into how it mitigates catastrophic distribution shifts, and empirically demonstrate its superiority through extensive experiments based on four rehearsal-based baselines and three public continual learning benchmarks.

Yichen Wu, Hongming Piao, Long-Kai Huang et al.

Continual Learning (CL) with foundation models has recently emerged as a promising paradigm to exploit abundant knowledge acquired during pre-training for tackling sequential tasks. However, existing prompt-based and Low-Rank Adaptation-based (LoRA-based) methods often require expanding a prompt/LoRA pool or retaining samples of previous tasks, which poses significant scalability challenges as the number of tasks grows. To address these limitations, we propose Scalable Decoupled LoRA (SD-LoRA) for class incremental learning, which continually separates the learning of the magnitude and direction of LoRA components without rehearsal. Our empirical and theoretical analysis reveals that SD-LoRA tends to follow a low-loss trajectory and converges to an overlapping low-loss region for all learned tasks, resulting in an excellent stability-plasticity trade-off. Building upon these insights, we introduce two variants of SD-LoRA with further improved parameter efficiency. All parameters of SD-LoRAs can be end-to-end optimized for CL objectives. Meanwhile, they support efficient inference by allowing direct evaluation with the finally trained model, obviating the need for component selection. Extensive experiments across multiple CL benchmarks and foundation models consistently validate the effectiveness of SD-LoRA. The code is available at https://github.com/WuYichen-97/SD-Lora-CL.

Wenyang Wei, Yang yang, Xixi Jia et al.

We present IllumFlow, a novel framework that synergizes conditional Rectified Flow (CRF) with Retinex theory for low-light image enhancement (LLIE). Our model addresses low-light enhancement through separate optimization of illumination and reflectance components, effectively handling both lighting variations and noise. Specifically, we first decompose an input image into reflectance and illumination components following Retinex theory. To model the wide dynamic range of illumination variations in low-light images, we propose a conditional rectified flow framework that represents illumination changes as a continuous flow field. While complex noise primarily resides in the reflectance component, we introduce a denoising network, enhanced by flow-derived data augmentation, to remove reflectance noise and chromatic aberration while preserving color fidelity. IllumFlow enables precise illumination adaptation across lighting conditions while naturally supporting customizable brightness enhancement. Extensive experiments on low-light enhancement and exposure correction demonstrate superior quantitative and qualitative performance over existing methods.

Xueqing Sun, Renzhen Wang, Quanziang Wang et al. · harvard

Pseudo-labeling is a commonly used paradigm in semi-supervised learning, yet its application to semi-supervised regression (SSR) remains relatively under-explored. Unlike classification, where pseudo-labels are discrete and confidence-based filtering is effective, SSR involves continuous outputs with heteroscedastic noise, making it challenging to assess pseudo-label reliability. As a result, naive pseudo-labeling can lead to error accumulation and overfitting to incorrect labels. To address this, we propose an uncertainty-aware pseudo-labeling framework that dynamically adjusts pseudo-label influence from a bi-level optimization perspective. By jointly minimizing empirical risk over all data and optimizing uncertainty estimates to enhance generalization on labeled data, our method effectively mitigates the impact of unreliable pseudo-labels. We provide theoretical insights and extensive experiments to validate our approach across various benchmark SSR datasets, and the results demonstrate superior robustness and performance compared to existing methods. Our code is available at https://github.com/sxq/Heteroscedastic-Pseudo-Labels.

Renzhen Wang, De cai, Kaiwen Xiao et al.

Hierarchical classification aims to sort the object into a hierarchical structure of categories. For example, a bird can be categorized according to a three-level hierarchy of order, family, and species. Existing methods commonly address hierarchical classification by decoupling it into a series of multi-class classification tasks. However, such a multi-task learning strategy fails to fully exploit the correlation among various categories across different levels of the hierarchy. In this paper, we propose Label Hierarchy Transition (LHT), a unified probabilistic framework based on deep learning, to address the challenges of hierarchical classification. The LHT framework consists of a transition network and a confusion loss. The transition network focuses on explicitly learning the label hierarchy transition matrices, which has the potential to effectively encode the underlying correlations embedded within class hierarchies. The confusion loss encourages the classification network to learn correlations across different label hierarchies during training. The proposed framework can be readily adapted to any existing deep network with only minor modifications. We experiment with a series of public benchmark datasets for hierarchical classification problems, and the results demonstrate the superiority of our approach beyond current state-of-the-art methods. Furthermore, we extend our proposed LHT framework to the skin lesion diagnosis task and validate its great potential in computer-aided diagnosis. The code of our method is available at \href{https://github.com/renzhenwang/label-hierarchy-transition}{https://github.com/renzhenwang/label-hierarchy-transition}.

Huai Chen, Renzhen Wang, Xiuying Wang et al.

Contrastive learning, which aims to capture general representation from unlabeled images to initialize the medical analysis models, has been proven effective in alleviating the high demand for expensive annotations. Current methods mainly focus on instance-wise comparisons to learn the global discriminative features, however, pretermitting the local details to distinguish tiny anatomical structures, lesions, and tissues. To address this challenge, in this paper, we propose a general unsupervised representation learning framework, named local discrimination (LD), to learn local discriminative features for medical images by closely embedding semantically similar pixels and identifying regions of similar structures across different images. Specifically, this model is equipped with an embedding module for pixel-wise embedding and a clustering module for generating segmentation. And these two modules are unified through optimizing our novel region discrimination loss function in a mutually beneficial mechanism, which enables our model to reflect structure information as well as measure pixel-wise and region-wise similarity. Furthermore, based on LD, we propose a center-sensitive one-shot landmark localization algorithm and a shape-guided cross-modality segmentation model to foster the generalizability of our model. When transferred to downstream tasks, the learned representation by our method shows a better generalization, outperforming representation from 18 state-of-the-art (SOTA) methods and winning 9 out of all 12 downstream tasks. Especially for the challenging lesion segmentation tasks, the proposed method achieves significantly better performances. The source codes are publicly available at https://github.com/HuaiChen-1994/LDLearning.

Zhiwu Wang, Yichen Wu, Renzhen Wang et al. · harvard

Class-Incremental Learning (CIL) aims to prevent catastrophic forgetting of previously learned classes while sequentially incorporating new ones. The more challenging Few-shot CIL (FSCIL) setting further complicates this by providing only a limited number of samples for each new class, increasing the risk of overfitting in addition to standard CIL challenges. While catastrophic forgetting has been extensively studied, overfitting in FSCIL, especially with large foundation models, has received less attention. To fill this gap, we propose the Singular Value Fine-tuning for FSCIL (SVFCL) and compared it with existing approaches for adapting foundation models to FSCIL, which primarily build on Parameter Efficient Fine-Tuning (PEFT) methods like prompt tuning and Low-Rank Adaptation (LoRA). Specifically, SVFCL applies singular value decomposition to the foundation model weights, keeping the singular vectors fixed while fine-tuning the singular values for each task, and then merging them. This simple yet effective approach not only alleviates the forgetting problem but also mitigates overfitting more effectively while significantly reducing trainable parameters. Extensive experiments on four benchmark datasets, along with visualizations and ablation studies, validate the effectiveness of SVFCL. The code will be made available.

Quanziang Wang, Renzhen Wang, Yuexiang Li et al.

Continual learning is a promising machine learning paradigm to learn new tasks while retaining previously learned knowledge over streaming training data. Till now, rehearsal-based methods, keeping a small part of data from old tasks as a memory buffer, have shown good performance in mitigating catastrophic forgetting for previously learned knowledge. However, most of these methods typically treat each new task equally, which may not adequately consider the relationship or similarity between old and new tasks. Furthermore, these methods commonly neglect sample importance in the continual training process and result in sub-optimal performance on certain tasks. To address this challenging problem, we propose Relational Experience Replay (RER), a bi-level learning framework, to adaptively tune task-wise relationships and sample importance within each task to achieve a better `stability' and `plasticity' trade-off. As such, the proposed method is capable of accumulating new knowledge while consolidating previously learned old knowledge during continual learning. Extensive experiments conducted on three publicly available datasets (i.e., CIFAR-10, CIFAR-100, and Tiny ImageNet) show that the proposed method can consistently improve the performance of all baselines and surpass current state-of-the-art methods.

Quanziang Wang, Renzhen Wang, Yuexiang Li et al.

Location information is proven to benefit the deep learning models on capturing the manifold structure of target objects, and accordingly boosts the accuracy of medical image segmentation. However, most existing methods encode the location information in an implicit way, e.g. the distance transform maps, which describe the relative distance from each pixel to the contour boundary, for the network to learn. These implicit approaches do not fully exploit the position information (i.e. absolute location) of targets. In this paper, we propose a novel loss function, namely residual moment (RM) loss, to explicitly embed the location information of segmentation targets during the training of deep learning networks. Particularly, motivated by image moments, the segmentation prediction map and ground-truth map are weighted by coordinate information. Then our RM loss encourages the networks to maintain the consistency between the two weighted maps, which promotes the segmentation networks to easily locate the targets and extract manifold-structure-related features. We validate the proposed RM loss by conducting extensive experiments on two publicly available datasets, i.e., 2D optic cup and disk segmentation and 3D left atrial segmentation. The experimental results demonstrate the effectiveness of our RM loss, which significantly boosts the accuracy of segmentation networks.

Huai Chen, Jieyu Li, Renzhen Wang et al.

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation learning methods require a large amount of annotated data, and unsupervised discriminative representation learning distinguishes different images by learning a global feature, both of which are not suitable for localized medical image analysis tasks. In order to avoid the limitations of these two methods, we introduce local discrimination into unsupervised representation learning in this work. The model contains two branches: one is an embedding branch which learns an embedding function to disperse dissimilar pixels over a low-dimensional hypersphere; and the other is a clustering branch which learns a clustering function to classify similar pixels into the same cluster. These two branches are trained simultaneously in a mutually beneficial pattern, and the learnt local discriminative representations are able to well measure the similarity of local image regions. These representations can be transferred to enhance various downstream tasks. Meanwhile, they can also be applied to cluster anatomical structures from unlabeled medical images under the guidance of topological priors from simulation or other structures with similar topological characteristics. The effectiveness and usefulness of the proposed method are demonstrated by enhancing various downstream tasks and clustering anatomical structures in retinal images and chest X-ray images.

Renzhen Wang, Kaiqin Hu, Yanwen Zhu et al.

Deep neural networks often degrade significantly when training data suffer from class imbalance problems. Existing approaches, e.g., re-sampling and re-weighting, commonly address this issue by rearranging the label distribution of training data to train the networks fitting well to the implicit balanced label distribution. However, most of them hinder the representative ability of learned features due to insufficient use of intra/inter-sample information of training data. To address this issue, we propose meta feature modulator (MFM), a meta-learning framework to model the difference between the long-tailed training data and the balanced meta data from the perspective of representation learning. Concretely, we employ learnable hyper-parameters (dubbed modulation parameters) to adaptively scale and shift the intermediate features of classification networks, and the modulation parameters are optimized together with the classification network parameters guided by a small amount of balanced meta data. We further design a modulator network to guide the generation of the modulation parameters, and such a meta-learner can be readily adapted to train the classification network on other long-tailed datasets. Extensive experiments on benchmark vision datasets substantiate the superiority of our approach on long-tailed recognition tasks beyond other state-of-the-art methods.

Shuxin Wang, Shilei Cao, Dong Wei et al.

We introduce a one-shot segmentation method to alleviate the burden of manual annotation for medical images. The main idea is to treat one-shot segmentation as a classical atlas-based segmentation problem, where voxel-wise correspondence from the atlas to the unlabelled data is learned. Subsequently, segmentation label of the atlas can be transferred to the unlabelled data with the learned correspondence. However, since ground truth correspondence between images is usually unavailable, the learning system must be well-supervised to avoid mode collapse and convergence failure. To overcome this difficulty, we resort to the forward-backward consistency, which is widely used in correspondence problems, and additionally learn the backward correspondences from the warped atlases back to the original atlas. This cycle-correspondence learning design enables a variety of extra, cycle-consistency-based supervision signals to make the training process stable, while also boost the performance. We demonstrate the superiority of our method over both deep learning-based one-shot segmentation methods and a classical multi-atlas segmentation method via thorough experiments.