Shengkai Li

Renxing Li, Weiyi Tang, Peiqi Li et al.

Objective. Elevated intracranial pressure (ICP) is recognized as a biomarker of secondary brain injury, with a significant linear correlation observed between optic nerve sheath diameter (ONSD) and ICP. Frequent monitoring of ONSD could effectively support dynamic evaluation of ICP. However, ONSD measurement is heavily reliant on the operator's experience and skill, particularly in manually selecting the optimal frame from ultrasound sequences and measuring ONSD. Approach. This paper presents a novel method to automatically identify the optimal frame from video sequences for ONSD measurement by employing the Kernel Correlation Filter (KCF) tracking algorithm and Simple Linear Iterative Clustering (SLIC) segmentation algorithm. The optic nerve sheath is mapped and measured using a Gaussian Mixture Model (GMM) combined with a KL-divergence-based method. Results. When compared with the average measurements of two expert clinicians, the proposed method achieved a mean error, mean squared deviation, and intraclass correlation coefficient (ICC) of 0.04, 0.054, and 0.782, respectively. Significance. The findings suggest that this method provides highly accurate automated ONSD measurements, showing potential for clinical application.

Jiayuan She, Lin Shi, Peiqi Li et al.

Background. Infectious diseases, particularly COVID-19, continue to be a significant global health issue. Although many countries have reduced or stopped large-scale testing measures, the detection of such diseases remains a propriety. Objective. This study aims to develop a novel, lightweight deep neural network for efficient, accurate, and cost-effective detection of COVID-19 using a nasal breathing audio data collected via smartphones. Methodology. Nasal breathing audio from 128 patients diagnosed with the Omicron variant was collected. Mel-Frequency Cepstral Coefficients (MFCCs), a widely used feature in speech and sound analysis, were employed for extracting important characteristics from the audio signals. Additional feature selection was performed using Random Forest (RF) and Principal Component Analysis (PCA) for dimensionality reduction. A Dense-ReLU-Dropout model was trained with K-fold cross-validation (K=3), and performance metrics like accuracy, precision, recall, and F1-score were used to evaluate the model. Results. The proposed model achieved 97% accuracy in detecting COVID-19 from nasal breathing sounds, outperforming state-of-the-art methods such as those by [23] and [13]. Our Dense-ReLU-Dropout model, using RF and PCA for feature selection, achieves high accuracy with greater computational efficiency compared to existing methods that require more complex models or larger datasets. Conclusion. The findings suggest that the proposed method holds significant potential for clinical implementation, advancing smartphone-based diagnostics in infectious diseases. The Dense-ReLU-Dropout model, combined with innovative feature processing techniques, offers a promising approach for efficient and accurate COVID-19 detection, showcasing the capabilities of mobile device-based diagnostics

Shengkai Li, Hussain N. Gynai, Steven Tarr et al.

Systems consisting of spheres rolling on elastic membranes have been used to introduce a core conceptual idea of General Relativity (GR): how curvature guides the movement of matter. However, such schemes cannot accurately represent relativistic dynamics in the laboratory because of the dominance of dissipation and external gravitational fields. Here we demonstrate that an ``active" object (a wheeled robot), which moves in a straight line on level ground and can alter its speed depending on the curvature of the deformable terrain it moves on, can exactly capture dynamics in curved relativistic spacetimes. Via the systematic study of the robot's dynamics in the radial and orbital directions, we develop a mapping of the emergent trajectories of a wheeled vehicle on a spandex membrane to the motion in a curved spacetime. Our mapping demonstrates how the driven robot's dynamics mix space and time in a metric, and shows how active particles do not necessarily follow geodesics in the real space but instead follow geodesics in a fiducial spacetime. The mapping further reveals how parameters such as the membrane elasticity and instantaneous speed allow the programming of a desired spacetime, such as the Schwarzschild metric near a non-rotating blackhole. Our mapping and framework facilitate creation of a robophysical analog to a general relativistic system in the laboratory at low cost that can provide insights into active matter in deformable environments and robot exploration in complex landscapes.

Shengkai Li, Bahnisikha Dutta, Sarah Cannon et al.

Active matter physics and swarm robotics have provided powerful tools for the study and control of ensembles driven by internal sources. At the macroscale, controlling swarms typically utilizes significant memory, processing power, and coordination unavailable at the microscale, e.g., for colloidal robots, which could be useful for fighting disease, fabricating intelligent textiles, and designing nanocomputers. To develop principles that that can leverage physics of interactions and thus can be utilized across scales, we take a two-pronged approach: a theoretical abstraction of self-organizing particle systems and an experimental robot system of active cohesive granular matter that intentionally lacks digital electronic computation and communication, using minimal (or no) sensing and control, to test theoretical predictions. We consider the problems of aggregation, dispersion, and collective transport. As predicted by the theory, as a parameter representing interparticle attraction increases, the robots transition from a dispersed phase to an aggregated one, forming a dense, compact collective. When aggregated, the collective can transport non-robot "impurities" in their environment, thus performing an emergent task driven by the physics underlying the transition. These results point to a fruitful interplay between algorithm design and active matter robophysics that can result in new nonequilibrium physics and principles for programming collectives without the need for complex algorithms or capabilities.

Shengkai Li, Yasemin Ozkan Aydin, Charles Xiao et al.

In many systems motion occurs on deformed and deformable surfaces, setting up the possibility for dynamical interactions solely mediated by the coupling of the entities with their environment. Here we study the "two-body" dynamics of robot locomotion on a highly deformable spandex membrane in two scenarios: one in which a robot orbits a large central depression and the other where the two robots affect each other's motion solely through mutual environmental deformations. Inspired by the resemblance of the orbits of the single robot with those of general relativistic orbits around black holes, we recast the vehicle plus membrane dynamics in physical space into the geodesic motion of a "test particle" in a fiducial curved space-time and demonstrate how this framework facilitates understanding the observed dynamics. The two-robot problem also exhibits a resemblance with Einstein's general relativistic view of gravity, which in the words of Wheeler: "spacetime tells matter how to move; matter tells spacetime how to curve." We generalize this case the mapping to include a reciprocal coupling that translates into robotic curvature-based control schemes which modify interaction (promoting avoidance or aggregation) without long-range sensing. Our work provides a starting point for developing a mechanical analog gravity system as well as develops a framework that can provide insights into active matter in deformable environments and robot exploration in complex landscapes.

Sarah Cannon, Joshua J. Daymude, William Savoie et al.

Smarticles, or smart active particles, are small robots equipped with only basic movement and sensing abilities that are incapable of rotating or displacing individually. We study the ensemble behavior of smarticles, i.e., the behavior a collective of these very simple computational elements can achieve, and how such behavior can be implemented using minimal programming. We show that an ensemble of smarticles constrained to remain close to one another (which we call a supersmarticle), achieves directed locomotion toward or away from a light source, a phenomenon known as phototaxing. We present experimental and theoretical models of phototactic supersmarticles that collectively move with a directed displacement in response to light. The motion of the supersmarticle is approximately Brownian, and is a result of chaotic interactions among smarticles. The system can be directed by introducing asymmetries among the individual smarticle's behavior, in our case by varying activity levels in response to light, resulting in supersmarticle biased motion.