Viola Chen

1paper

1 Paper

LGOct 22, 2021
Patient level simulation and reinforcement learning to discover novel strategies for treating ovarian cancer

Brian Murphy, Mustafa Nasir-Moin, Grace von Oiste et al.

The prognosis for patients with epithelial ovarian cancer remains dismal despite improvements in survival for other cancers. Treatment involves multiple lines of chemotherapy and becomes increasingly heterogeneous after first-line therapy. Reinforcement learning with real-world outcomes data has the potential to identify novel treatment strategies to improve overall survival. We design a reinforcement learning environment to model epithelial ovarian cancer treatment trajectories and use model free reinforcement learning to investigate therapeutic regimens for simulated patients.