Giovanni Petri

Gabriele D'Acunto, Francesco Bonchi, Gianmarco De Francisci Morales et al.

The bulk of the research effort on brain connectivity revolves around statistical associations among brain regions, which do not directly relate to the causal mechanisms governing brain dynamics. Here we propose the multiscale causal backbone (MCB) of brain dynamics, shared by a set of individuals across multiple temporal scales, and devise a principled methodology to extract it. Our approach leverages recent advances in multiscale causal structure learning and optimizes the trade-off between the model fit and its complexity. Empirical assessment on synthetic data shows the superiority of our methodology over a baseline based on canonical functional connectivity networks. When applied to resting-state fMRI data, we find sparse MCBs for both the left and right brain hemispheres. Thanks to its multiscale nature, our approach shows that at low-frequency bands, causal dynamics are driven by brain regions associated with high-level cognitive functions; at higher frequencies instead, nodes related to sensory processing play a crucial role. Finally, our analysis of individual multiscale causal structures confirms the existence of a causal fingerprint of brain connectivity, thus supporting the existing extensive research in brain connectivity fingerprinting from a causal perspective.

Marco Nurisso, Jesseba Fernando, Raj Deshpande et al.

Intelligent systems must deploy internal representations that are simultaneously structured -- to support broad generalization -- and selective -- to preserve input identity. We expose a fundamental limit on this tradeoff. For any model whose representational similarity between inputs decays with finite semantic resolution $\varepsilon$, we derive closed-form expressions that pin its probability of correct generalization $p_S$ and identification $p_I$ to a universal Pareto front independent of input space geometry. Extending the analysis to noisy, heterogeneous spaces and to $n>2$ inputs predicts a sharp $1/n$ collapse of multi-input processing capacity and a non-monotonic optimum for $p_S$. A minimal ReLU network trained end-to-end reproduces these laws: during learning a resolution boundary self-organizes and empirical $(p_S,p_I)$ trajectories closely follow theoretical curves for linearly decaying similarity. Finally, we demonstrate that the same limits persist in two markedly more complex settings -- a convolutional neural network and state-of-the-art vision-language models -- confirming that finite-resolution similarity is a fundamental emergent informational constraint, not merely a toy-model artifact. Together, these results provide an exact theory of the generalization-identification trade-off and clarify how semantic resolution shapes the representational capacity of deep networks and brains alike.

Jacob Andreas, Gašper Beguš, Michael M. Bronstein et al.

The past decade has witnessed a groundbreaking rise of machine learning for human language analysis, with current methods capable of automatically accurately recovering various aspects of syntax and semantics - including sentence structure and grounded word meaning - from large data collections. Recent research showed the promise of such tools for analyzing acoustic communication in nonhuman species. We posit that machine learning will be the cornerstone of future collection, processing, and analysis of multimodal streams of data in animal communication studies, including bioacoustic, behavioral, biological, and environmental data. Cetaceans are unique non-human model species as they possess sophisticated acoustic communications, but utilize a very different encoding system that evolved in an aquatic rather than terrestrial medium. Sperm whales, in particular, with their highly-developed neuroanatomical features, cognitive abilities, social structures, and discrete click-based encoding make for an excellent starting point for advanced machine learning tools that can be applied to other animals in the future. This paper details a roadmap toward this goal based on currently existing technology and multidisciplinary scientific community effort. We outline the key elements required for the collection and processing of massive bioacoustic data of sperm whales, detecting their basic communication units and language-like higher-level structures, and validating these models through interactive playback experiments. The technological capabilities developed by such an undertaking are likely to yield cross-applications and advancements in broader communities investigating non-human communication and animal behavioral research.

Jean-Gabriel Young, Giovanni Petri, Tiago P. Peixoto

Networks can describe the structure of a wide variety of complex systems by specifying which pairs of entities in the system are connected. While such pairwise representations are flexible, they are not necessarily appropriate when the fundamental interactions involve more than two entities at the same time. Pairwise representations nonetheless remain ubiquitous, because higher-order interactions are often not recorded explicitly in network data. Here, we introduce a Bayesian approach to reconstruct latent higher-order interactions from ordinary pairwise network data. Our method is based on the principle of parsimony and only includes higher-order structures when there is sufficient statistical evidence for them. We demonstrate its applicability to a wide range of datasets, both synthetic and empirical.

Jacob Charles Wright Billings, Mirko Hu, Giulia Lerda et al.

Topological representations are rapidly becoming a popular way to capture and encode higher-order interactions in complex systems. They have found applications in disciplines as different as cancer genomics, brain function, and computational social science, in representing both descriptive features of data and inference models. While intense research has focused on the connectivity and homological features of topological representations, surprisingly scarce attention has been given to the investigation of the community structures of simplicial complexes. To this end, we adopt recent advances in symbolic embeddings to compute and visualize the community structures of simplicial complexes. We first investigate the stability properties of embedding obtained for synthetic simplicial complexes to the presence of higher order interactions. We then focus on complexes arising from social and brain functional data and show how higher order interactions can be leveraged to improve clustering detection and assess the effect of higher order interaction on individual nodes. We conclude delineating limitations and directions for extension of this work.