Guoan Tang

Zheng Chu, Huiming Fan, Jingchang Chen et al.

Although large language models (LLMs) have demonstrated remarkable reasoning capabilities, they still face challenges in knowledge-intensive multi-hop reasoning. Recent work explores iterative retrieval to address complex problems. However, the lack of intermediate guidance often results in inaccurate retrieval and flawed intermediate reasoning, leading to incorrect reasoning. To address these, we propose Self-Critique Guided Iterative Reasoning (SiGIR), which uses self-critique feedback to guide the iterative reasoning process. Specifically, through end-to-end training, we enable the model to iteratively address complex problems via question decomposition. Additionally, the model is able to self-evaluate its intermediate reasoning steps. During iterative reasoning, the model engages in branching exploration and employs self-evaluation to guide the selection of promising reasoning trajectories. Extensive experiments on three multi-hop reasoning datasets demonstrate the effectiveness of our proposed method, surpassing the previous SOTA by $8.6\%$. Furthermore, our thorough analysis offers insights for future research. Our code, data, and models are available at Github: https://github.com/zchuz/SiGIR-MHQA.

Y. Du, G. Wu, G. Tang et al.

Synthetic data generated by large language models has become integral to modern NLP training pipelines, from bootstrapping reasoning capabilities to augmenting instruction-following datasets. While recent work demonstrates successful applications maintaining high external data ratios, systematic understanding of how synthetic data proportion affects model behavior across different scales remains limited. This paper presents a controlled empirical study examining model performance, calibration, and output characteristics when trained on varying synthetic-to-external data ratios. Using the Pythia model suite (410M-12B parameters) across five diverse tasks, we evaluate models after one to three training iterations with synthetic data proportions ranging from 0-50\%. Our key findings include: models maintain stable performance with up to 20\% synthetic data, but degradation accelerates beyond 30\%; larger models (6.9B-12B) show greater robustness to synthetic data than smaller models (410M-1.4B); calibration degradation precedes accuracy loss, providing an early warning signal; and task characteristics matter, with reasoning tasks degrading faster than retrieval tasks under synthetic data training. Importantly, we find that current best practices, such as those employed in STaR and Self-Instruct systems that maintain greater than 80\% external data, operate well within safe regimes identified by our experiments. We provide practical guidance for practitioners on synthetic data budgets based on model scale and task requirements, alongside detailed comparison with concurrent work including Shumailov et al.'s model collapse findings.

Guo Tang, Songhan Jiang, Jinpeng Lu et al.

Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images (WSIs). Recent advancements in multiple instance learning have significantly improved the efficiency of survival analysis. However, existing methods often struggle to balance the modeling of long-range spatial relationships with local contextual dependencies and typically lack inherent interpretability, limiting their clinical utility. To address these challenges, we propose the Interpretable Pathology Graph-Transformer (IPGPhormer), a novel framework that captures the characteristics of the tumor microenvironment and models their spatial dependencies across the tissue. IPGPhormer uniquely provides interpretability at both tissue and cellular levels without requiring post-hoc manual annotations, enabling detailed analyses of individual WSIs and cross-cohort assessments. Comprehensive evaluations on four public benchmark datasets demonstrate that IPGPhormer outperforms state-of-the-art methods in both predictive accuracy and interpretability. In summary, our method, IPGPhormer, offers a promising tool for cancer prognosis assessment, paving the way for more reliable and interpretable decision-support systems in pathology. The code is publicly available at https://anonymous.4open.science/r/IPGPhormer-6EEB.