Weidi Xie

Chaoyi Wu, Pengcheng Qiu, Jinxin Liu et al.

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering, MedS-Bench spans 11 high-level clinical tasks, including clinical report summarization, treatment recommendations, diagnosis, named entity recognition, and medical concept explanation, among others. We evaluated six leading LLMs, e.g., MEDITRON, Mistral, InternLM 2, Llama 3, GPT-4, and Claude-3.5 using few-shot prompting, and found that even the most sophisticated models struggle with these complex tasks. To address these limitations, we developed MedS-Ins, a large-scale instruction tuning dataset for medicine. MedS-Ins comprises 58 medically oriented language corpora, totaling 13.5 million samples across 122 tasks. To demonstrate the dataset's utility, we conducted a proof-of-concept experiment by performing instruction tuning on a lightweight, open-source medical language model. The resulting model, MMedIns-Llama 3, significantly outperformed existing models across nearly all clinical tasks. To promote further advancements in the application of LLMs to clinical challenges, we have made the MedS-Ins dataset fully accessible and invite the research community to contribute to its expansion.Additionally, we have launched a dynamic leaderboard for MedS-Bench, which we plan to regularly update the test set to track progress and enhance the adaptation of general LLMs to the medical domain. Leaderboard: https://henrychur.github.io/MedS-Bench/. Github: https://github.com/MAGIC-AI4Med/MedS-Ins.

Junyu Xie, Tengda Han, Max Bain et al.

Our objective is to generate Audio Descriptions (ADs) for both movies and TV series in a training-free manner. We use the power of off-the-shelf Visual-Language Models (VLMs) and Large Language Models (LLMs), and develop visual and text prompting strategies for this task. Our contributions are three-fold: (i) We demonstrate that a VLM can successfully name and refer to characters if directly prompted with character information through visual indications without requiring any fine-tuning; (ii) A two-stage process is developed to generate ADs, with the first stage asking the VLM to comprehensively describe the video, followed by a second stage utilising a LLM to summarise dense textual information into one succinct AD sentence; (iii) A new dataset for TV audio description is formulated. Our approach, named AutoAD-Zero, demonstrates outstanding performance (even competitive with some models fine-tuned on ground truth ADs) in AD generation for both movies and TV series, achieving state-of-the-art CRITIC scores.

Yibin Yan, Jilan Xu, Shangzhe Di et al.

Modern visual agents require representations that are general, causal, and physically structured to operate in real-time streaming environments. However, current vision foundation models remain fragmented, specializing narrowly in image semantic perception, offline temporal modeling, or spatial geometry. This paper introduces OmniStream, a unified streaming visual backbone that effectively perceives, reconstructs, and acts from diverse visual inputs. By incorporating causal spatiotemporal attention and 3D rotary positional embeddings (3D-RoPE), our model supports efficient, frame-by-frame online processing of video streams via a persistent KV-cache. We pre-train OmniStream using a synergistic multi-task framework coupling static and temporal representation learning, streaming geometric reconstruction, and vision-language alignment on 29 datasets. Extensive evaluations show that, even with a strictly frozen backbone, OmniStream achieves consistently competitive performance with specialized experts across image and video probing, streaming geometric reconstruction, complex video and spatial reasoning, as well as robotic manipulation (unseen at training). Rather than pursuing benchmark-specific dominance, our work demonstrates the viability of training a single, versatile vision backbone that generalizes across semantic, spatial, and temporal reasoning, i.e., a more meaningful step toward general-purpose visual understanding for interactive and embodied agents.

Luoyi Sun, Xiao Zhou, Zeqian Li et al.

Large Audio-Language Models (ALMs) have recently demonstrated remarkable capabilities in holistic audio understanding, yet they remain unreliable for temporal grounding, i.e., the task of pinpointing exactly when an event occurs within long-form audio. This limitation stems from two factors: training data dominated by clip-level supervision lacking precise timestamps, and benchmarks that fail to simulate real-world scenarios where short events are obscured by dense background sounds. In this paper, we introduce SpotSound, an audio language model designed for grounding audio events. SpotSound incorporates a novel training objective, specifically designed to suppress hallucinated timestamps for events absent from the input. Additionally, we present SpotSound-Bench, a challenging temporal grounding benchmark where target events occupy less than ~10\% of each clip, creating a rigorous `needle-in-a-haystack' evaluation. Experiments demonstrate that SpotSound achieves state-of-the-art results on temporal grounding benchmarks while maintaining robust performance across general downstream audio-language tasks. Code, models and benchmark are released on https://loiesun.github.io/spotsound/

Yikun Liu, Yuan Liu, Shangzhe Di et al.

Multimodal Large Language Models (MLLMs) have recently achieved remarkable success in visual-language understanding, demonstrating superior high-level semantic alignment within their vision encoders. An important question thus arises: Can these encoders serve as versatile vision backbones, capable of reliably performing classic vision-centric tasks as well? To address the question, we make the following contributions: (i) we identify that the vision encoders within MLLMs exhibit deficiencies in their dense feature representations, as evidenced by their suboptimal performance on dense prediction tasks (e.g., semantic segmentation, depth estimation); (ii) we propose VersaViT, a well-rounded vision transformer that instantiates a novel multi-task framework for collaborative post-training. This framework facilitates the optimization of the vision backbone via lightweight task heads with multi-granularity supervision; (iii) extensive experiments across various downstream tasks demonstrate the effectiveness of our method, yielding a versatile vision backbone suited for both language-mediated reasoning and pixel-level understanding.

Cheng Liang, Chaoyi Wu, Weike Zhao et al.

Recent progress in large-scale CLIP-like vision-language models(VLMs) has greatly advanced medical image analysis. However, most existing medical VLMs still rely on coarse image-text contrastive objectives and fail to capture the systematic visual knowledge encoded in well-defined medical phenotype ontologies. To address this gap, we construct PhenoKG, the first large-scale, phenotype-centric multimodal knowledge graph that encompasses over 520K high-quality image-text pairs linked to more than 3,000 phenotypes. Building upon PhenoKG, we propose PhenoLIP, a novel pretraining framework that explicitly incorporates structured phenotype knowledge into medical VLMs through a two-stage process. We first learn a knowledge-enhanced phenotype embedding space from textual ontology data and then distill this structured knowledge into multimodal pretraining via a teacher-guided knowledge distillation objective. To support evaluation, we further introduce PhenoBench, an expert-verified benchmark designed for phenotype recognition, comprising over 7,800 image--caption pairs covering more than 1,000 phenotypes. Extensive experiments demonstrate that PhenoLIP outperforms previous state-of-the-art baselines, improving upon BiomedCLIP in phenotype classification accuracy by 8.85\% and BIOMEDICA in cross-modal retrieval by 15.03%, underscoring the value of integrating phenotype-centric priors into medical VLMs for structured and interpretable medical image understanding.

Pengcheng Qiu, Chaoyi Wu, Shuyu Liu et al.

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored, particularly in evaluating the quality of their reasoning processes alongside final outputs. Here, we introduce MedR-Bench, a benchmarking dataset of 1,453 structured patient cases, annotated with reasoning references derived from clinical case reports. Spanning 13 body systems and 10 specialties, it includes both common and rare diseases. To comprehensively evaluate LLM performance, we propose a framework encompassing three critical examination recommendation, diagnostic decision-making, and treatment planning, simulating the entire patient care journey. To assess reasoning quality, we present the Reasoning Evaluator, a novel automated system that objectively scores free-text reasoning responses based on efficiency, actuality, and completeness using dynamic cross-referencing and evidence checks. Using this benchmark, we evaluate five state-of-the-art reasoning LLMs, including DeepSeek-R1, OpenAI-o3-mini, and Gemini-2.0-Flash Thinking, etc. Our results show that current LLMs achieve over 85% accuracy in relatively simple diagnostic tasks when provided with sufficient examination results. However, performance declines in more complex tasks, such as examination recommendation and treatment planning. While reasoning outputs are generally reliable, with factuality scores exceeding 90%, critical reasoning steps are frequently missed. These findings underscore both the progress and limitations of clinical LLMs. Notably, open-source models like DeepSeek-R1 are narrowing the gap with proprietary systems, highlighting their potential to drive accessible and equitable advancements in healthcare.

Ziqing Fan, Cheng Liang, Chaoyi Wu et al.

Recent advances in reasoning-enhanced large language models (LLMs) and multimodal LLMs (MLLMs) have significantly improved performance in complex tasks, yet medical AI models often overlook the structured reasoning processes inherent in clinical practice. In this work, we present ChestX-Reasoner, a radiology diagnosis MLLM designed to leverage process supervision mined directly from clinical reports, reflecting the step-by-step reasoning followed by radiologists. We construct a large dataset by extracting and refining reasoning chains from routine radiology reports. Our two-stage training framework combines supervised fine-tuning and reinforcement learning guided by process rewards to better align model reasoning with clinical standards. We introduce RadRBench-CXR, a comprehensive benchmark featuring 59K visual question answering samples with 301K clinically validated reasoning steps, and propose RadRScore, a metric evaluating reasoning factuality, completeness, and effectiveness. ChestX-Reasoner outperforms existing medical and general-domain MLLMs in both diagnostic accuracy and reasoning ability, achieving 16%, 5.9%, and 18% improvements in reasoning ability compared to the best medical MLLM, the best general MLLM, and its base model, respectively, as well as 3.3%, 24%, and 27% improvements in outcome accuracy. All resources are open-sourced to facilitate further research in medical reasoning MLLMs.

Yikun Liu, Jiangchao Yao, Weidi Xie et al.

Composed Image Retrieval (CIR) aims to retrieve a target image based on a query composed of a reference image, and a relative caption that specifies the desired modification. Despite the rapid development of CIR models, their performance is not well characterized by existing benchmarks, which inherently contain indeterminate queries degrading the evaluation (i.e., multiple candidate images, rather than solely the target image, meet the query criteria), and have not considered their effectiveness in the context of the multi-round system. Motivated by this, we consider improving the evaluation procedure from two aspects: 1) we introduce FISD, a Fully-Informed Semantically-Diverse benchmark, which employs generative models to precisely control the variables of reference-target image pairs, enabling a more accurate evaluation of CIR methods across six dimensions, without query ambiguity; 2) we propose an automatic multi-round agentic evaluation framework to probe the potential of the existing models in the interactive scenarios. By observing how models adapt and refine their choices over successive rounds of queries, this framework provides a more realistic appraisal of their efficacy in practical applications. Extensive experiments and comparisons prove the value of our novel evaluation on typical CIR methods.

Haicheng Wang, Yuan Liu, Yikun Liu et al.

Multimodal Large Language Models (MLLMs) have recently demonstrated remarkable capabilities in cross-modal understanding and generation. However, the rapid growth of visual token sequences--especially in long-video and streaming scenarios--poses a major challenge to their scalability and real-world deployment. Thus, we introduce POINTS-Long, a native dual-mode MLLM featuring dynamic visual token scaling inspired by the human visual system. The model supports two complementary perception modes: focus mode and standby mode, enabling users to dynamically trade off efficiency and accuracy during inference. On fine-grained visual tasks, the focus mode retains the optimal performance, while on long-form general visual understanding, the standby mode retains 97.7-99.7% of the original accuracy using only 1/40-1/10th of the visual tokens. Moreover, POINTS-Long natively supports streaming visual understanding via a dynamically detachable KV-cache design, allowing efficient maintenance of ultra-long visual memory. Our work provides new insights into the design of future MLLMs and lays the foundation for adaptive and efficient long-form visual understanding.

Yeyao Ma, Chen Li, Xiaosong Zhang et al.

Post-training of flow matching models-aligning the output distribution with a high-quality target-is mathematically equivalent to imitation learning. While Supervised Fine-Tuning mimics expert demonstrations effectively, it cannot correct policy drift in unseen states. Preference optimization methods address this but require costly preference pairs or reward modeling. We propose Flow Matching Adversarial Imitation Learning (FAIL), which minimizes policy-expert divergence through adversarial training without explicit rewards or pairwise comparisons. We derive two algorithms: FAIL-PD exploits differentiable ODE solvers for low-variance pathwise gradients, while FAIL-PG provides a black-box alternative for discrete or computationally constrained settings. Fine-tuning FLUX with only 13,000 demonstrations from Nano Banana pro, FAIL achieves competitive performance on prompt following and aesthetic benchmarks. Furthermore, the framework generalizes effectively to discrete image and video generation, and functions as a robust regularizer to mitigate reward hacking in reward-based optimization. Code and data are available at https://github.com/HansPolo113/FAIL.

Qiaoyu Zheng, Yuze Sun, Chaoyi Wu et al.

Accurate diagnosis with medical large language models is hindered by knowledge gaps and hallucinations. Retrieval and tool-augmented methods help, but their impact is limited by weak use of external knowledge and poor feedback-reasoning traceability. To address these challenges, We introduce Deep-DxSearch, an agentic RAG system trained end-to-end with reinforcement learning (RL) that enables steer tracebale retrieval-augmented reasoning for medical diagnosis. In Deep-DxSearch, we first construct a large-scale medical retrieval corpus comprising patient records and reliable medical knowledge sources to support retrieval-aware reasoning across diagnostic scenarios. More crutially, we frame the LLM as the core agent and the retrieval corpus as its environment, using tailored rewards on format, retrieval, reasoning structure, and diagnostic accuracy, thereby evolving the agentic RAG policy from large-scale data through RL. Experiments demonstrate that our end-to-end agentic RL training framework consistently outperforms prompt-engineering and training-free RAG approaches across multiple data centers. After training, Deep-DxSearch achieves substantial gains in diagnostic accuracy, surpassing strong diagnostic baselines such as GPT-4o, DeepSeek-R1, and other medical-specific frameworks for both common and rare disease diagnosis under in-distribution and out-of-distribution settings. Moreover, ablation studies on reward design and retrieval corpus components confirm their critical roles, underscoring the uniqueness and effectiveness of our approach compared with traditional implementations. Finally, case studies and interpretability analyses highlight improvements in Deep-DxSearch's diagnostic policy, providing deeper insight into its performance gains and supporting clinicians in delivering more reliable and precise preliminary diagnoses. See https://github.com/MAGIC-AI4Med/Deep-DxSearch.

Yudi Shi, Shangzhe Di, Qirui Chen et al.

Video reasoning constitutes a comprehensive assessment of a model's capabilities, as it demands robust perceptual and interpretive skills, thereby serving as a means to explore the boundaries of model performance. While recent research has leveraged text-centric Chain-of-Thought reasoning to augment these capabilities, such approaches frequently suffer from representational mismatch and restricted by limited perceptual acuity. To address these limitations, we propose Weaver, a novel, end-to-end trainable multimodal reasoning agentic system. Weaver empowers its policy model to dynamically invoke diverse tools throughout the reasoning process, enabling progressive acquisition of crucial visual cues and construction of authentic multimodal reasoning trajectories. Furthermore, we integrate a reinforcement learning algorithm to allow the system to freely explore strategies for employing and combining these tools with trajectory-free data. Extensive experiments demonstrate that our system, Weaver, enhances performance on several complex video reasoning benchmarks, particularly those involving long videos.

Görkay Aydemir, Fatma Güney, Weidi Xie

Models for long-term point tracking are typically trained on large synthetic datasets. The performance of these models degrades in real-world videos due to different characteristics and the absence of dense ground-truth annotations. Self-training on unlabeled videos has been explored as a practical solution, but the quality of pseudo-labels strongly depends on the reliability of teacher models, which vary across frames and scenes. In this paper, we address the problem of real-world fine-tuning and introduce verifier, a meta-model that learns to assess the reliability of tracker predictions and guide pseudo-label generation. Given candidate trajectories from multiple pretrained trackers, the verifier evaluates them per frame and selects the most trustworthy predictions, resulting in high-quality pseudo-label trajectories. When applied for fine-tuning, verifier-guided pseudo-labeling substantially improves the quality of supervision and enables data-efficient adaptation to unlabeled videos. Extensive experiments on four real-world benchmarks demonstrate that our approach achieves state-of-the-art results while requiring less data than prior self-training methods. Project page: https://kuis-ai.github.io/track_on_r

Shangzhe Di, Zhonghua Zhai, Weidi Xie

Current visual representation learning remains bifurcated: vision-language models (e.g., CLIP) excel at global semantic alignment but lack spatial precision, while self-supervised methods (e.g., MAE, DINO) capture intricate local structures yet struggle with high-level semantic context. We argue that these paradigms are fundamentally complementary and can be integrated into a principled multi-task framework, further enhanced by dense spatial supervision. We introduce MTV, a multi-task visual pretraining framework that jointly optimizes a shared backbone across vision-language contrastive, self-supervised, and dense spatial objectives. To mitigate the need for manual annotations, we leverage high-capacity "expert" models -- such as Depth Anything V2 and OWLv2 -- to synthesize dense, structured pseudo-labels at scale. Beyond the framework, we provide a systematic investigation into the mechanics of multi-task visual learning, analyzing: (i) the marginal gain of each objective, (ii) task synergies versus interference, and (iii) scaling behavior across varying data and model scales. Our results demonstrate that MTV achieves "best-of-both-worlds" performance, significantly enhancing fine-grained spatial reasoning without compromising global semantic understanding. Our findings suggest that multi-task learning, fueled by high-quality pseudo-supervision, is a scalable path toward more general visual encoders.

Jiayuan Rao, Zifeng Li, Haoning Wu et al.

Recent advances in soccer understanding have demonstrated rapid progress, yet existing research predominantly focuses on isolated or narrow tasks. To bridge this gap, we propose a comprehensive framework for holistic soccer understanding. Concretely, we make the following contributions in this paper: (i) we construct SoccerWiki, the first large-scale multimodal soccer knowledge base, integrating rich domain knowledge about players, teams, referees, and venues to enable knowledge-driven reasoning; (ii) we present SoccerBench, the largest and most comprehensive soccer-specific benchmark, featuring around 10K multimodal (text, image, video) multi-choice QA pairs across 13 distinct tasks; (iii) we introduce SoccerAgent, a novel multi-agent system that decomposes complex soccer questions via collaborative reasoning, leveraging domain expertise from SoccerWiki and achieving robust performance; (iv) extensive evaluations and comparisons with representative MLLMs on SoccerBench highlight the superiority of our agentic system.

Yanxu Meng, Haoning Wu, Ya Zhang et al.

3D content generation has recently attracted significant research interest due to its applications in VR/AR and embodied AI. In this work, we address the challenging task of synthesizing multiple 3D assets within a single scene image. Concretely, our contributions are fourfold: (i) we present SceneGen, a novel framework that takes a scene image and corresponding object masks as input, simultaneously producing multiple 3D assets with geometry and texture. Notably, SceneGen operates with no need for optimization or asset retrieval; (ii) we introduce a novel feature aggregation module that integrates local and global scene information from visual and geometric encoders within the feature extraction module. Coupled with a position head, this enables the generation of 3D assets and their relative spatial positions in a single feedforward pass; (iii) we demonstrate SceneGen's direct extensibility to multi-image input scenarios. Despite being trained solely on single-image inputs, our architectural design enables improved generation performance with multi-image inputs; and (iv) extensive quantitative and qualitative evaluations confirm the efficiency and robust generation abilities of our approach. We believe this paradigm offers a novel solution for high-quality 3D content generation, potentially advancing its practical applications in downstream tasks. The code and model will be publicly available at: https://mengmouxu.github.io/SceneGen.

Ziheng Zhao, Lisong Dai, Ya Zhang et al.

Automated interpretation of CT images-particularly localizing and describing abnormal findings across multi-plane and whole-body scans-remains a significant challenge in clinical radiology. This work aims to address this challenge through four key contributions: (i) On taxonomy, we collaborate with senior radiologists to propose a comprehensive hierarchical classification system, with 404 representative abnormal findings across all body regions; (ii) On data, we contribute a dataset containing over 14.5K CT images from multiple planes and all human body regions, and meticulously provide grounding annotations for over 19K abnormalities, each linked to the detailed description and cast into the taxonomy; (iii) On model development, we propose OmniAbnorm-CT, which can automatically ground and describe abnormal findings on multi-plane and whole-body CT images based on text queries, while also allowing flexible interaction through visual prompts; (iv) On evaluation, we establish three representative tasks based on real clinical scenarios, and introduce a clinically grounded metric to assess abnormality descriptions. Through extensive experiments, we show that OmniAbnorm-CT can significantly outperform existing methods in both internal and external validations, and across all the tasks.

Guanqi Zhan, Xianzheng Ma, Weidi Xie et al.

We study the task of predicting dynamic physical properties from videos. More specifically, we consider physical properties that require temporal information to be inferred: elasticity of a bouncing object, viscosity of a flowing liquid, and dynamic friction of an object sliding on a surface. To this end, we make the following contributions: (i) We collect a new video dataset for each physical property, consisting of synthetic training and testing splits, as well as a real split for real world evaluation. (ii) We explore three ways to infer the physical property from videos: (a) an oracle method where we supply the visual cues that intrinsically reflect the property using classical computer vision techniques; (b) a simple read out mechanism using a visual prompt and trainable prompt vector for cross-attention on pre-trained video generative and self-supervised models; and (c) prompt strategies for Multi-modal Large Language Models (MLLMs). (iii) We show that video foundation models trained in a generative or self-supervised manner achieve a similar performance, though behind that of the oracle, and MLLMs are currently inferior to the other models, though their performance can be improved through suitable prompting.

Zhongrui Gui, Junyu Xie, Tengda Han et al. · oxford

Animated movies are captivating for their unique character designs and imaginative storytelling, yet they pose significant challenges for existing recognition systems. Unlike the consistent visual patterns detected by conventional face recognition methods, animated characters exhibit extreme diversity in their appearance, motion, and deformation. In this work, we propose an audio-visual pipeline to enable automatic and robust animated character recognition, and thereby enhance character-centric understanding of animated movies. Central to our approach is the automatic construction of an audio-visual character bank from online sources. This bank contains both visual exemplars and voice (audio) samples for each character, enabling subsequent multi-modal character recognition despite long-tailed appearance distributions. Building on accurate character recognition, we explore two downstream applications: Audio Description (AD) generation for visually impaired audiences, and character-aware subtitling for the hearing impaired. To support research in this domain, we introduce CMD-AM, a new dataset of 75 animated movies with comprehensive annotations. Our character-centric pipeline demonstrates significant improvements in both accessibility and narrative comprehension for animated content over prior face-detection-based approaches. For the code and dataset, visit https://www.robots.ox.ac.uk/~vgg/research/animated_ad/.

Jinghao Feng, Qiaoyu Zheng, Chaoyi Wu et al.

Agentic AI systems have gained significant attention for their ability to autonomously perform complex tasks. However, their reliance on well-prepared tools limits their applicability in the medical domain, which requires to train specialized models. In this paper, we make three contributions: (i) We present M3Builder, a novel multi-agent system designed to automate machine learning (ML) in medical imaging. At its core, M3Builder employs four specialized agents that collaborate to tackle complex, multi-step medical ML workflows, from automated data processing and environment configuration to self-contained auto debugging and model training. These agents operate within a medical imaging ML workspace, a structured environment designed to provide agents with free-text descriptions of datasets, training codes, and interaction tools, enabling seamless communication and task execution. (ii) To evaluate progress in automated medical imaging ML, we propose M3Bench, a benchmark comprising four general tasks on 14 training datasets, across five anatomies and three imaging modalities, covering both 2D and 3D data. (iii) We experiment with seven state-of-the-art large language models serving as agent cores for our system, such as Claude series, GPT-4o, and DeepSeek-V3. Compared to existing ML agentic designs, M3Builder shows superior performance on completing ML tasks in medical imaging, achieving a 94.29% success rate using Claude-3.7-Sonnet as the agent core, showing huge potential towards fully automated machine learning in medical imaging.

Weike Zhao, Chaoyi Wu, Xiaoman Zhang et al.

This paper introduces a novel, entity-aware metric, termed as Radiological Report (Text) Evaluation (RaTEScore), to assess the quality of medical reports generated by AI models. RaTEScore emphasizes crucial medical entities such as diagnostic outcomes and anatomical details, and is robust against complex medical synonyms and sensitive to negation expressions. Technically, we developed a comprehensive medical NER dataset, RaTE-NER, and trained an NER model specifically for this purpose. This model enables the decomposition of complex radiological reports into constituent medical entities. The metric itself is derived by comparing the similarity of entity embeddings, obtained from a language model, based on their types and relevance to clinical significance. Our evaluations demonstrate that RaTEScore aligns more closely with human preference than existing metrics, validated both on established public benchmarks and our newly proposed RaTE-Eval benchmark.