Xiaojun Zeng

Viktor Schlegel, Hao Li, Yuping Wu et al. · tencent-ai

This paper describes PULSAR, our system submission at the ImageClef 2023 MediQA-Sum task on summarising patient-doctor dialogues into clinical records. The proposed framework relies on domain-specific pre-training, to produce a specialised language model which is trained on task-specific natural data augmented by synthetic data generated by a black-box LLM. We find limited evidence towards the efficacy of domain-specific pre-training and data augmentation, while scaling up the language model yields the best performance gains. Our approach was ranked second and third among 13 submissions on task B of the challenge. Our code is available at https://github.com/yuping-wu/PULSAR.

Hao Li, Yuping Wu, Viktor Schlegel et al. · tencent-ai

Medical progress notes play a crucial role in documenting a patient's hospital journey, including his or her condition, treatment plan, and any updates for healthcare providers. Automatic summarisation of a patient's problems in the form of a problem list can aid stakeholders in understanding a patient's condition, reducing workload and cognitive bias. BioNLP 2023 Shared Task 1A focuses on generating a list of diagnoses and problems from the provider's progress notes during hospitalisation. In this paper, we introduce our proposed approach to this task, which integrates two complementary components. One component employs large language models (LLMs) for data augmentation; the other is an abstractive summarisation LLM with a novel pre-training objective for generating the patients' problems summarised as a list. Our approach was ranked second among all submissions to the shared task. The performance of our model on the development and test datasets shows that our approach is more robust on unknown data, with an improvement of up to 3.1 points over the same size of the larger model.

Yuchong Li, Xiaojun Zeng, Chihua Fang et al.

Hepato-pancreato-biliary (HPB) disorders represent a global public health challenge due to their high morbidity and mortality. Although large language models (LLMs) have shown promising performance in general medical question-answering tasks, the current evaluation benchmarks are mostly derived from standardized examinations or manually designed questions, lacking HPB coverage and clinical cases. To address these issues, we systematically eatablish an HPB disease evaluation benchmark comprising 3,535 closed-ended multiple-choice questions and 337 open-ended real diagnosis cases, which encompasses all the 33 main categories and 465 subcategories of HPB diseases defined in the International Statistical Classification of Diseases, 10th Revision (ICD-10). The multiple-choice questions are curated from public datasets and synthesized data, and the clinical cases are collected from prestigious medical journals, case-sharing platforms, and collaborating hospitals. By evalauting commercial and open-source general and medical LLMs on our established benchmark, namely ClinBench-HBP, we find that while commercial LLMs perform competently on medical exam questions, they exhibit substantial performance degradation on HPB diagnosis tasks, especially on complex, inpatient clinical cases. Those medical LLMs also show limited generalizability to HPB diseases. Our results reveal the critical limitations of current LLMs in the domain of HPB diseases, underscoring the imperative need for future medical LLMs to handle real, complex clinical diagnostics rather than simple medical exam questions. The benchmark will be released at https://clinbench-hpb.github.io.

Ching-Hsun. Tseng, Liu-Hsueh. Cheng, Shin-Jye. Lee et al.

In deep learning, optimization plays a vital role. By focusing on image classification, this work investigates the pros and cons of the widely used optimizers, and proposes a new optimizer: Perturbated Unit Gradient Descent (PUGD) algorithm with extending normalized gradient operation in tensor within perturbation to update in unit space. Via a set of experiments and analyses, we show that PUGD is locally bounded updating, which means the updating from time to time is controlled. On the other hand, PUGD can push models to a flat minimum, where the error remains approximately constant, not only because of the nature of avoiding stationary points in gradient normalization but also by scanning sharpness in the unit ball. From a series of rigorous experiments, PUGD helps models to gain a state-of-the-art Top-1 accuracy in Tiny ImageNet and competitive performances in CIFAR- {10, 100}. We open-source our code at link: https://github.com/hanktseng131415go/PUGD.