Bojian Hou

Ruochen Jin, Bojian Hou, Jiancong Xiao et al.

In recent years, task arithmetic has garnered increasing attention. This approach edits pre-trained models directly in weight space by combining the fine-tuned weights of various tasks into a unified model. Its efficiency and cost-effectiveness stem from its training-free combination, contrasting with traditional methods that require model training on large datasets for multiple tasks. However, applying such a unified model to individual tasks can lead to interference from other tasks (lack of weight disentanglement). To address this issue, Neural Tangent Kernel (NTK) linearization has been employed to leverage a "kernel behavior", facilitating weight disentanglement and mitigating adverse effects from unrelated tasks. Despite its benefits, NTK linearization presents drawbacks, including doubled training costs, as well as reduced performance of individual models. To tackle this problem, we propose a simple yet effective and efficient method that is to finetune the attention modules only in the Transformer. Our study reveals that the attention modules exhibit kernel behavior, and fine-tuning the attention modules only significantly improves weight disentanglement. To further understand how our method improves the weight disentanglement of task arithmetic, we present a comprehensive study of task arithmetic by differentiating the role of the representation module and task-specific module. In particular, we find that the representation module plays an important role in improving weight disentanglement whereas the task-specific modules such as the classification heads can degenerate the weight disentanglement performance. (The code is available at https://github.com/kyrie-23/task_arithmetic_tangent)

Heng Lian, John Scovil Atwood, Bojian Hou et al.

This paper investigates a new online learning problem with doubly-streaming data, where the data streams are described by feature spaces that constantly evolve, with new features emerging and old features fading away. The challenges of this problem are two folds: 1) Data samples ceaselessly flowing in may carry shifted patterns over time, requiring learners to update hence adapt on-the-fly. 2) Newly emerging features are described by very few samples, resulting in weak learners that tend to make error predictions. A plausible idea to overcome the challenges is to establish relationship between the pre-and-post evolving feature spaces, so that an online learner can leverage the knowledge learned from the old features to better the learning performance on the new features. Unfortunately, this idea does not scale up to high-dimensional media streams with complex feature interplay, which suffers an tradeoff between onlineness (biasing shallow learners) and expressiveness(requiring deep learners). Motivated by this, we propose a novel OLD^3S paradigm, where a shared latent subspace is discovered to summarize information from the old and new feature spaces, building intermediate feature mapping relationship. A key trait of OLD^3S is to treat the model capacity as a learnable semantics, yields optimal model depth and parameters jointly, in accordance with the complexity and non-linearity of the input data streams in an online fashion. Both theoretical analyses and empirical studies substantiate the viability and effectiveness of our proposal.

Davoud Ataee Tarzanagh, Parvin Nazari, Bojian Hou et al.

This paper introduces \textit{online bilevel optimization} in which a sequence of time-varying bilevel problems is revealed one after the other. We extend the known regret bounds for online single-level algorithms to the bilevel setting. Specifically, we provide new notions of \textit{bilevel regret}, develop an online alternating time-averaged gradient method that is capable of leveraging smoothness, and give regret bounds in terms of the path-length of the inner and outer minimizer sequences.

Bojian Hou, Hongming Li, Zhicheng Jiao et al.

Conventional survival analysis methods are typically ineffective to characterize heterogeneity in the population while such information can be used to assist predictive modeling. In this study, we propose a hybrid survival analysis method, referred to as deep clustering survival machines, that combines the discriminative and generative mechanisms. Similar to the mixture models, we assume that the timing information of survival data is generatively described by a mixture of certain numbers of parametric distributions, i.e., expert distributions. We learn weights of the expert distributions for individual instances according to their features discriminatively such that each instance's survival information can be characterized by a weighted combination of the learned constant expert distributions. This method also facilitates interpretable subgrouping/clustering of all instances according to their associated expert distributions. Extensive experiments on both real and synthetic datasets have demonstrated that the method is capable of obtaining promising clustering results and competitive time-to-event predicting performance.

Parvin Nazari, Bojian Hou, Davoud Ataee Tarzanagh et al.

Online bilevel optimization (OBO) is a powerful framework for machine learning problems where both outer and inner objectives evolve over time, requiring dynamic updates. Current OBO approaches rely on deterministic \textit{window-smoothed} regret minimization, which may not accurately reflect system performance when functions change rapidly. In this work, we introduce a novel search direction and show that both first- and zeroth-order (ZO) stochastic OBO algorithms leveraging this direction achieve sublinear {stochastic bilevel regret without window smoothing}. Beyond these guarantees, our framework enhances efficiency by: (i) reducing oracle dependence in hypergradient estimation, (ii) updating inner and outer variables alongside the linear system solution, and (iii) employing ZO-based estimation of Hessians, Jacobians, and gradients. Experiments on online parametric loss tuning and black-box adversarial attacks validate our approach.

Jing-Xiao Liao, Bo-Jian Hou, Hang-Cheng Dong et al.

Inspired by the complexity and diversity of biological neurons, a quadratic neuron is proposed to replace the inner product in the current neuron with a simplified quadratic function. Employing such a novel type of neurons offers a new perspective on developing deep learning. When analyzing quadratic neurons, we find that there exists a function such that a heterogeneous network can approximate it well with a polynomial number of neurons but a purely conventional or quadratic network needs an exponential number of neurons to achieve the same level of error. Encouraged by this inspiring theoretical result on heterogeneous networks, we directly integrate conventional and quadratic neurons in an autoencoder to make a new type of heterogeneous autoencoders. To our best knowledge, it is the first heterogeneous autoencoder that is made of different types of neurons. Next, we apply the proposed heterogeneous autoencoder to unsupervised anomaly detection for tabular data and bearing fault signals. The anomaly detection faces difficulties such as data unknownness, anomaly feature heterogeneity, and feature unnoticeability, which is suitable for the proposed heterogeneous autoencoder. Its high feature representation ability can characterize a variety of anomaly data (heterogeneity), discriminate the anomaly from the normal (unnoticeability), and accurately learn the distribution of normal samples (unknownness). Experiments show that heterogeneous autoencoders perform competitively compared to other state-of-the-art models.

Zhuoping Zhou, Davoud Ataee Tarzanagh, Bojian Hou et al.

This paper investigates fairness and bias in Canonical Correlation Analysis (CCA), a widely used statistical technique for examining the relationship between two sets of variables. We present a framework that alleviates unfairness by minimizing the correlation disparity error associated with protected attributes. Our approach enables CCA to learn global projection matrices from all data points while ensuring that these matrices yield comparable correlation levels to group-specific projection matrices. Experimental evaluation on both synthetic and real-world datasets demonstrates the efficacy of our method in reducing correlation disparity error without compromising CCA accuracy.

Dawei Li, Shu Yang, Zhen Tan et al.

Recent advancements in large language models (LLMs) have achieved promising performances across various applications. Nonetheless, the ongoing challenge of integrating long-tail knowledge continues to impede the seamless adoption of LLMs in specialized domains. In this work, we introduce DALK, a.k.a. Dynamic Co-Augmentation of LLMs and KG, to address this limitation and demonstrate its ability on studying Alzheimer's Disease (AD), a specialized sub-field in biomedicine and a global health priority. With a synergized framework of LLM and KG mutually enhancing each other, we first leverage LLM to construct an evolving AD-specific knowledge graph (KG) sourced from AD-related scientific literature, and then we utilize a coarse-to-fine sampling method with a novel self-aware knowledge retrieval approach to select appropriate knowledge from the KG to augment LLM inference capabilities. The experimental results, conducted on our constructed AD question answering (ADQA) benchmark, underscore the efficacy of DALK. Additionally, we perform a series of detailed analyses that can offer valuable insights and guidelines for the emerging topic of mutually enhancing KG and LLM. We will release the code and data at https://github.com/David-Li0406/DALK.

Mingquan Lin, Yuyun Xiao, Bojian Hou et al.

In the United States, primary open-angle glaucoma (POAG) is the leading cause of blindness, especially among African American and Hispanic individuals. Deep learning has been widely used to detect POAG using fundus images as its performance is comparable to or even surpasses diagnosis by clinicians. However, human bias in clinical diagnosis may be reflected and amplified in the widely-used deep learning models, thus impacting their performance. Biases may cause (1) underdiagnosis, increasing the risks of delayed or inadequate treatment, and (2) overdiagnosis, which may increase individuals' stress, fear, well-being, and unnecessary/costly treatment. In this study, we examined the underdiagnosis and overdiagnosis when applying deep learning in POAG detection based on the Ocular Hypertension Treatment Study (OHTS) from 22 centers across 16 states in the United States. Our results show that the widely-used deep learning model can underdiagnose or overdiagnose underserved populations. The most underdiagnosed group is female younger (< 60 yrs) group, and the most overdiagnosed group is Black older (>=60 yrs) group. Biased diagnosis through traditional deep learning methods may delay disease detection, treatment and create burdens among under-served populations, thereby, raising ethical concerns about using deep learning models in ophthalmology clinics.

Zhuoping Zhou, Davoud Ataee Tarzanagh, Bojian Hou et al.

This paper examines the issue of fairness in the estimation of graphical models (GMs), particularly Gaussian, Covariance, and Ising models. These models play a vital role in understanding complex relationships in high-dimensional data. However, standard GMs can result in biased outcomes, especially when the underlying data involves sensitive characteristics or protected groups. To address this, we introduce a comprehensive framework designed to reduce bias in the estimation of GMs related to protected attributes. Our approach involves the integration of the pairwise graph disparity error and a tailored loss function into a nonsmooth multi-objective optimization problem, striving to achieve fairness across different sensitive groups while maintaining the effectiveness of the GMs. Experimental evaluations on synthetic and real-world datasets demonstrate that our framework effectively mitigates bias without undermining GMs' performance.

Dayang Wang, Feng-Lei Fan, Bo-Jian Hou et al.

A neural network with the widely-used ReLU activation has been shown to partition the sample space into many convex polytopes for prediction. However, the parameterized way a neural network and other machine learning models use to partition the space has imperfections, \textit{e}.\textit{g}., the compromised interpretability for complex models, the inflexibility in decision boundary construction due to the generic character of the model, and the risk of being trapped into shortcut solutions. In contrast, although the non-parameterized models can adorably avoid or downplay these issues, they are usually insufficiently powerful either due to over-simplification or the failure to accommodate the manifold structures of data. In this context, we first propose a new type of machine learning models referred to as Manifoldron that directly derives decision boundaries from data and partitions the space via manifold structure discovery. Then, we systematically analyze the key characteristics of the Manifoldron such as manifold characterization capability and its link to neural networks. The experimental results on 4 synthetic examples, 20 public benchmark datasets, and 1 real-world application demonstrate that the proposed Manifoldron performs competitively compared to the mainstream machine learning models. We have shared our code in \url{https://github.com/wdayang/Manifoldron} for free download and evaluation.

Weiqing He, Bojian Hou, Tianqi Shang et al.

The widespread adoption of large language models (LLMs) has created an urgent need for robust tools to detect LLM-generated text, especially in light of \textit{paraphrasing} techniques that often evade existing detection methods. To address this challenge, we present a novel semantic-enhanced framework for detecting LLM-generated text (SEFD) that leverages a retrieval-based mechanism to fully utilize text semantics. Our framework improves upon existing detection methods by systematically integrating retrieval-based techniques with traditional detectors, employing a carefully curated retrieval mechanism that strikes a balance between comprehensive coverage and computational efficiency. We showcase the effectiveness of our approach in sequential text scenarios common in real-world applications, such as online forums and Q\&A platforms. Through comprehensive experiments across various LLM-generated texts and detection methods, we demonstrate that our framework substantially enhances detection accuracy in paraphrasing scenarios while maintaining robustness for standard LLM-generated content.

Sophie Kearney, Shu Yang, Zixuan Wen et al.

Early and accurate diagnosis of Alzheimer's disease (AD), a complex neurodegenerative disorder, requires analysis of heterogeneous biomarkers (e.g., neuroimaging, genetic risk factors, cognitive tests, and cerebrospinal fluid proteins) typically represented in a tabular format. With flexible few-shot reasoning, multimodal integration, and natural-language-based interpretability, large language models (LLMs) offer unprecedented opportunities for prediction with structured biomedical data. We propose a novel framework called TAP-GPT, Tabular Alzheimer's Prediction GPT, that adapts TableGPT2, a multimodal tabular-specialized LLM originally developed for business intelligence tasks, for AD diagnosis using structured biomarker data with small sample sizes. Our approach constructs few-shot tabular prompts using in-context learning examples from structured biomedical data and finetunes TableGPT2 using the parameter-efficient qLoRA adaption for a clinical binary classification task of AD or cognitively normal (CN). The TAP-GPT framework harnesses the powerful tabular understanding ability of TableGPT2 and the encoded prior knowledge of LLMs to outperform more advanced general-purpose LLMs and a tabular foundation model (TFM) developed for prediction tasks. To our knowledge, this is the first application of LLMs to the prediction task using tabular biomarker data, paving the way for future LLM-driven multi-agent frameworks in biomedical informatics.

Bojian Hou, Hao Zhang, Gur Ladizhinsky et al.

Abstruse learning algorithms and complex datasets increasingly characterize modern clinical decision support systems (CDSS). As a result, clinicians cannot easily or rapidly scrutinize the CDSS recommendation when facing a difficult diagnosis or treatment decision in practice. Over-trust or under-trust are frequent. Prior research has explored supporting such assessments by explaining DST data inputs and algorithmic mechanisms. This paper explores a different approach: Providing precisely relevant, scientific evidence from biomedical literature. We present a proof-of-concept system, Clinical Evidence Engine, to demonstrate the technical and design feasibility of this approach across three domains (cardiovascular diseases, autism, cancer). Leveraging Clinical BioBERT, the system can effectively identify clinical trial reports based on lengthy clinical questions (e.g., "risks of catheter infection among adult patients in intensive care unit who require arterial catheters, if treated with povidone iodine-alcohol"). This capability enables the system to identify clinical trials relevant to diagnostic/treatment hypotheses -- a clinician's or a CDSS's. Further, Clinical Evidence Engine can identify key parts of a clinical trial abstract, including patient population (e.g., adult patients in intensive care unit who require arterial catheters), intervention (povidone iodine-alcohol), and outcome (risks of catheter infection). This capability opens up the possibility of enabling clinicians to 1) rapidly determine the match between a clinical trial and a clinical question, and 2) understand the result and contexts of the trial without extensive reading. We demonstrate this potential by illustrating two example use scenarios of the system. We discuss the idea of designing DST explanations not as specific to a DST or an algorithm, but as a domain-agnostic decision support infrastructure.

Bo-Jian Hou, Yu-Hu Yan, Peng Zhao et al.

Feature evolvable learning has been widely studied in recent years where old features will vanish and new features will emerge when learning with streams. Conventional methods usually assume that a label will be revealed after prediction at each time step. However, in practice, this assumption may not hold whereas no label will be given at most time steps. A good solution is to leverage the technique of manifold regularization to utilize the previous similar data to assist the refinement of the online model. Nevertheless, this approach needs to store all previous data which is impossible in learning with streams that arrive sequentially in large volume. Thus we need a buffer to store part of them. Considering that different devices may have different storage budgets, the learning approaches should be flexible subject to the storage budget limit. In this paper, we propose a new setting: Storage-Fit Feature-Evolvable streaming Learning (SF$^2$EL) which incorporates the issue of rarely-provided labels into feature evolution. Our framework is able to fit its behavior to different storage budgets when learning with feature evolvable streams with unlabeled data. Besides, both theoretical and empirical results validate that our approach can preserve the merit of the original feature evolvable learning i.e., can always track the best baseline and thus perform well at any time step.

Bo-Jian Hou, Lijun Zhang, Zhi-Hua Zhou

Learning with feature evolution studies the scenario where the features of the data streams can evolve, i.e., old features vanish and new features emerge. Its goal is to keep the model always performing well even when the features happen to evolve. To tackle this problem, canonical methods assume that the old features will vanish simultaneously and the new features themselves will emerge simultaneously as well. They also assume there is an overlapping period where old and new features both exist when the feature space starts to change. However, in reality, the feature evolution could be unpredictable, which means the features can vanish or emerge arbitrarily, causing the overlapping period incomplete. In this paper, we propose a novel paradigm: Prediction with Unpredictable Feature Evolution (PUFE) where the feature evolution is unpredictable. To address this problem, we fill the incomplete overlapping period and formulate it as a new matrix completion problem. We give a theoretical bound on the least number of observed entries to make the overlapping period intact. With this intact overlapping period, we leverage an ensemble method to take the advantage of both the old and new feature spaces without manually deciding which base models should be incorporated. Theoretical and experimental results validate that our method can always follow the best base models and thus realize the goal of learning with feature evolution.

Bo-Jian Hou, Zhi-Hua Zhou

The interpretability of deep learning models has raised extended attention these years. It will be beneficial if we can learn an interpretable structure from deep learning models. In this paper, we focus on Recurrent Neural Networks~(RNNs) especially gated RNNs whose inner mechanism is still not clearly understood. We find that Finite State Automaton~(FSA) that processes sequential data has more interpretable inner mechanism according to the definition of interpretability and can be learned from RNNs as the interpretable structure. We propose two methods to learn FSA from RNN based on two different clustering methods. With the learned FSA and via experiments on artificial and real datasets, we find that FSA is more trustable than the RNN from which it learned, which gives FSA a chance to substitute RNNs in applications involving humans' lives or dangerous facilities. Besides, we analyze how the number of gates affects the performance of RNN. Our result suggests that gate in RNN is important but the less the better, which could be a guidance to design other RNNs. Finally, we observe that the FSA learned from RNN gives semantic aggregated states and its transition graph shows us a very interesting vision of how RNNs intrinsically handle text classification tasks.

Bo-Jian Hou, Lijun Zhang, Zhi-Hua Zhou

Learning with streaming data has attracted much attention during the past few years. Though most studies consider data stream with fixed features, in real practice the features may be evolvable. For example, features of data gathered by limited-lifespan sensors will change when these sensors are substituted by new ones. In this paper, we propose a novel learning paradigm: \emph{Feature Evolvable Streaming Learning} where old features would vanish and new features would occur. Rather than relying on only the current features, we attempt to recover the vanished features and exploit it to improve performance. Specifically, we learn two models from the recovered features and the current features, respectively. To benefit from the recovered features, we develop two ensemble methods. In the first method, we combine the predictions from two models and theoretically show that with the assistance of old features, the performance on new features can be improved. In the second approach, we dynamically select the best single prediction and establish a better performance guarantee when the best model switches. Experiments on both synthetic and real data validate the effectiveness of our proposal.