J. John Mann

Braja Gopal Patra, Lauren A. Lepow, Praneet Kasi Reddy Jagadeesh Kumar et al.

Background: Social support (SS) and social isolation (SI) are social determinants of health (SDOH) associated with psychiatric outcomes. In electronic health records (EHRs), individual-level SS/SI is typically documented as narrative clinical notes rather than structured coded data. Natural language processing (NLP) algorithms can automate the otherwise labor-intensive process of data extraction. Data and Methods: Psychiatric encounter notes from Mount Sinai Health System (MSHS, n=300) and Weill Cornell Medicine (WCM, n=225) were annotated and established a gold standard corpus. A rule-based system (RBS) involving lexicons and a large language model (LLM) using FLAN-T5-XL were developed to identify mentions of SS and SI and their subcategories (e.g., social network, instrumental support, and loneliness). Results: For extracting SS/SI, the RBS obtained higher macro-averaged f-scores than the LLM at both MSHS (0.89 vs. 0.65) and WCM (0.85 vs. 0.82). For extracting subcategories, the RBS also outperformed the LLM at both MSHS (0.90 vs. 0.62) and WCM (0.82 vs. 0.81). Discussion and Conclusion: Unexpectedly, the RBS outperformed the LLMs across all metrics. Intensive review demonstrates that this finding is due to the divergent approach taken by the RBS and LLM. The RBS were designed and refined to follow the same specific rules as the gold standard annotations. Conversely, the LLM were more inclusive with categorization and conformed to common English-language understanding. Both approaches offer advantages and are made available open-source for future testing.

Alexandra Fetsch, Iurii Savvateev, Racem Ben Romdhane et al.

Key global challenges of our times are characterized by complex interdependencies and can only be effectively addressed through an integrated, participatory effort. Conventional risk analysis frameworks often reduce complexity to ensure manageability, creating silos that hinder comprehensive solutions. A fundamental shift towards holistic strategies is essential to enable effective negotiations between different sectors and to balance the competing interests of stakeholders. However, achieving this balance is often hindered by limited time, vast amounts of information, and the complexity of integrating diverse perspectives. This study presents an AI-assisted negotiation framework that incorporates large language models (LLMs) and AI-based autonomous agents into a negotiation-centered risk analysis workflow. The framework enables stakeholders to simulate negotiations, systematically model dynamics, anticipate compromises, and evaluate solution impacts. By leveraging LLMs' semantic analysis capabilities we could mitigate information overload and augment decision-making process under time constraints. Proof-of-concept implementations were conducted in two real-world scenarios: (i) prudent use of a biopesticide, and (ii) targeted wild animal population control. Our work demonstrates the potential of AI-assisted negotiation to address the current lack of tools for cross-sectoral engagement. Importantly, the solution's open source, web based design, suits for application by a broader audience with limited resources and enables users to tailor and develop it for their own needs.