Xianyao Zheng

Qiangguo Jin, Xianyao Zheng, Hui Cui et al.

Medical visual question answering (Med-VQA) is a crucial multimodal task in clinical decision support and telemedicine. Recent self-attention based methods struggle to effectively handle cross-modal semantic alignments between vision and language. Moreover, classification-based methods rely on predefined answer sets. Treating this task as a simple classification problem may make it unable to adapt to the diversity of free-form answers and overlook the detailed semantic information of free-form answers. In order to tackle these challenges, we introduce a Cross-Mamba Interaction based Multi-Task Learning (CMI-MTL) framework that learns cross-modal feature representations from images and texts. CMI-MTL comprises three key modules: fine-grained visual-text feature alignment (FVTA), cross-modal interleaved feature representation (CIFR), and free-form answer-enhanced multi-task learning (FFAE). FVTA extracts the most relevant regions in image-text pairs through fine-grained visual-text feature alignment. CIFR captures cross-modal sequential interactions via cross-modal interleaved feature representation. FFAE leverages auxiliary knowledge from open-ended questions through free-form answer-enhanced multi-task learning, improving the model's capability for open-ended Med-VQA. Experimental results show that CMI-MTL outperforms the existing state-of-the-art methods on three Med-VQA datasets: VQA-RAD, SLAKE, and OVQA. Furthermore, we conduct more interpretability experiments to prove the effectiveness. The code is publicly available at https://github.com/BioMedIA-repo/CMI-MTL.

Xianyao Zheng, Hong Yu, Hui Cui et al.

Medical visual question answering (Med-VQA) is a crucial multimodal task in clinical decision support and telemedicine. Recent methods fail to fully leverage domain-specific medical knowledge, making it difficult to accurately associate lesion features in medical images with key diagnostic criteria. Additionally, classification-based approaches typically rely on predefined answer sets. Treating Med-VQA as a simple classification problem limits its ability to adapt to the diversity of free-form answers and may overlook detailed semantic information in those answers. To address these challenges, we propose a knowledge graph enhanced cross-Mamba interaction (KG-CMI) framework, which consists of a fine-grained cross-modal feature alignment (FCFA) module, a knowledge graph embedding (KGE) module, a cross-modal interaction representation (CMIR) module, and a free-form answer enhanced multi-task learning (FAMT) module. The KG-CMI learns cross-modal feature representations for images and texts by effectively integrating professional medical knowledge through a graph, establishing associations between lesion features and disease knowledge. Moreover, FAMT leverages auxiliary knowledge from open-ended questions, improving the model's capability for open-ended Med-VQA. Experimental results demonstrate that KG-CMI outperforms existing state-of-the-art methods on three Med-VQA datasets, i.e., VQA-RAD, SLAKE, and OVQA. Additionally, we conduct interpretability experiments to further validate the framework's effectiveness.