AINov 3, 2025
ExplicitLM: Decoupling Knowledge from Parameters via Explicit Memory BanksChengzhang Yu, Zening Lu, Chenyang Zheng et al.
Large language models suffer from knowledge staleness and lack of interpretability due to implicit knowledge storage across entangled network parameters, preventing targeted updates and reasoning transparency. We propose ExplicitLM, a novel architecture featuring a million-scale external memory bank storing human-readable knowledge as token sequences, enabling direct inspection and modification. We design a differentiable two-stage retrieval mechanism with efficient coarse-grained filtering via product key decomposition (reducing complexity from $\mathcal{O}(N \cdot |I|)$ to $\mathcal{O}(\sqrt{N} \cdot |I|)$) and fine-grained Gumbel-Softmax matching for end-to-end training. Inspired by dual-system cognitive theory, we partition knowledge into frozen explicit facts (20%) and learnable implicit patterns (80%), maintained through Exponential Moving Average updates for stability. ExplicitLM achieves up to 43.67% improvement on knowledge-intensive tasks versus standard Transformers, with 3.62$\times$ gains in low-data regimes (10k samples). Analysis shows strong correlations between memory retrieval and performance, with correct predictions achieving 49% higher hit rates. Unlike RAG systems with frozen retrieval, our jointly optimized architecture demonstrates that interpretable, updatable models can maintain competitive performance while providing unprecedented knowledge transparency.
AINov 3, 2025
From Passive to Proactive: A Multi-Agent System with Dynamic Task Orchestration for Intelligent Medical Pre-ConsultationChengZhang Yu, YingRu He, Hongyan Cheng et al.
Global healthcare systems face critical challenges from increasing patient volumes and limited consultation times, with primary care visits averaging under 5 minutes in many countries. While pre-consultation processes encompassing triage and structured history-taking offer potential solutions, they remain limited by passive interaction paradigms and context management challenges in existing AI systems. This study introduces a hierarchical multi-agent framework that transforms passive medical AI systems into proactive inquiry agents through autonomous task orchestration. We developed an eight-agent architecture with centralized control mechanisms that decomposes pre-consultation into four primary tasks: Triage ($T_1$), History of Present Illness collection ($T_2$), Past History collection ($T_3$), and Chief Complaint generation ($T_4$), with $T_1$--$T_3$ further divided into 13 domain-specific subtasks. Evaluated on 1,372 validated electronic health records from a Chinese medical platform across multiple foundation models (GPT-OSS 20B, Qwen3-8B, Phi4-14B), the framework achieved 87.0% accuracy for primary department triage and 80.5% for secondary department classification, with task completion rates reaching 98.2% using agent-driven scheduling versus 93.1% with sequential processing. Clinical quality scores from 18 physicians averaged 4.56 for Chief Complaints, 4.48 for History of Present Illness, and 4.69 for Past History on a 5-point scale, with consultations completed within 12.7 rounds for $T_2$ and 16.9 rounds for $T_3$. The model-agnostic architecture maintained high performance across different foundation models while preserving data privacy through local deployment, demonstrating the potential for autonomous AI systems to enhance pre-consultation efficiency and quality in clinical settings.
CVJul 25, 2025
CircuitProbe: Dissecting Spatiotemporal Visual Semantics with Circuit TracingYiming Zhang, Chengzhang Yu, Zhuokai Zhao et al.
The processing mechanisms underlying language and image understanding in large vision-language models (LVLMs) have been extensively studied. However, the internal reasoning mechanisms of LVLMs for spatiotemporal understanding remain poorly understood. In this work, we introduce a systematic, circuit-based framework designed to investigate how spatiotemporal visual semantics are represented and processed within these LVLMs. Specifically, our framework comprises three circuits: visual auditing circuit, semantic tracing circuit, and attention flow circuit. Through the lens of these circuits, we discover that visual semantics are highly localized to specific object tokens--removing these tokens can degrade model performance by up to 92.6%. Furthermore, we identify that interpretable concepts of objects and actions emerge and become progressively refined in the middle-to-late layers of LVLMs. In contrary to the current works that solely focus on objects in one image, we reveal that the middle-to-late layers of LVLMs exhibit specialized functional localization for spatiotemporal semantics. Our findings offer significant mechanistic insights into spatiotemporal semantics analysis of LVLMs, laying a foundation for designing more robust and interpretable models.
CLMay 6, 2025
FRAME: Feedback-Refined Agent Methodology for Enhancing Medical Research InsightsChengzhang Yu, Yiming Zhang, Zhixin Liu et al.
The automation of scientific research through large language models (LLMs) presents significant opportunities but faces critical challenges in knowledge synthesis and quality assurance. We introduce Feedback-Refined Agent Methodology (FRAME), a novel framework that enhances medical paper generation through iterative refinement and structured feedback. Our approach comprises three key innovations: (1) A structured dataset construction method that decomposes 4,287 medical papers into essential research components through iterative refinement; (2) A tripartite architecture integrating Generator, Evaluator, and Reflector agents that progressively improve content quality through metric-driven feedback; and (3) A comprehensive evaluation framework that combines statistical metrics with human-grounded benchmarks. Experimental results demonstrate FRAME's effectiveness, achieving significant improvements over conventional approaches across multiple models (9.91% average gain with DeepSeek V3, comparable improvements with GPT-4o Mini) and evaluation dimensions. Human evaluation confirms that FRAME-generated papers achieve quality comparable to human-authored works, with particular strength in synthesizing future research directions. The results demonstrated our work could efficiently assist medical research by building a robust foundation for automated medical research paper generation while maintaining rigorous academic standards.
CVFeb 22, 2024
A Self-supervised Pressure Map human keypoint Detection Approch: Optimizing Generalization and Computational Efficiency Across DatasetsChengzhang Yu, Xianjun Yang, Wenxia Bao et al.
In environments where RGB images are inadequate, pressure maps is a viable alternative, garnering scholarly attention. This study introduces a novel self-supervised pressure map keypoint detection (SPMKD) method, addressing the current gap in specialized designs for human keypoint extraction from pressure maps. Central to our contribution is the Encoder-Fuser-Decoder (EFD) model, which is a robust framework that integrates a lightweight encoder for precise human keypoint detection, a fuser for efficient gradient propagation, and a decoder that transforms human keypoints into reconstructed pressure maps. This structure is further enhanced by the Classification-to-Regression Weight Transfer (CRWT) method, which fine-tunes accuracy through initial classification task training. This innovation not only enhances human keypoint generalization without manual annotations but also showcases remarkable efficiency and generalization, evidenced by a reduction to only $5.96\%$ in FLOPs and $1.11\%$ in parameter count compared to the baseline methods.
AIJul 30, 2025
Collaborative Medical Triage under Uncertainty: A Multi-Agent Dynamic Matching ApproachHongyan Cheng, Chengzhang Yu, Yanshu Shi et al.
The post-pandemic surge in healthcare demand, coupled with critical nursing shortages, has placed unprecedented pressure on medical triage systems, necessitating innovative AI-driven solutions. We present a multi-agent interactive intelligent system for medical triage that addresses three fundamental challenges in current AI-based triage systems: inadequate medical specialization leading to misclassification, heterogeneous department structures across healthcare institutions, and inefficient detail-oriented questioning that impedes rapid triage decisions. Our system employs three specialized agents--RecipientAgent, InquirerAgent, and DepartmentAgent--that collaborate through Inquiry Guidance mechanism and Classification Guidance Mechanism to transform unstructured patient symptoms into accurate department recommendations. To ensure robust evaluation, we constructed a comprehensive Chinese medical triage dataset from "Ai Ai Yi Medical Network", comprising 3,360 real-world cases spanning 9 primary departments and 62 secondary departments. Experimental results demonstrate that our multi-agent system achieves 89.6% accuracy in primary department classification and 74.3% accuracy in secondary department classification after four rounds of patient interaction. The system's dynamic matching based guidance mechanisms enable efficient adaptation to diverse hospital configurations while maintaining high triage accuracy. We successfully developed this multi-agent triage system that not only adapts to organizational heterogeneity across healthcare institutions but also ensures clinically sound decision-making.