L. Taylor Davis

Rohun Tripathi, Vasu Singla, Mahyar Najibi et al.

The widely adopted sequential variant of Non Maximum Suppression (or Greedy-NMS) is a crucial module for object-detection pipelines. Unfortunately, for the region proposal stage of two/multi-stage detectors, NMS is turning out to be a latency bottleneck due to its sequential nature. In this article, we carefully profile Greedy-NMS iterations to find that a major chunk of computation is wasted in comparing proposals that are already far-away and have a small chance of suppressing each other. We address this issue by comparing only those proposals that are generated from nearby anchors. The translation-invariant property of the anchor lattice affords generation of a lookup table, which provides an efficient access to nearby proposals, during NMS. This leads to an Accelerated NMS algorithm which leverages Spatially Aware Priors, or ASAP-NMS, and improves the latency of the NMS step from 13.6ms to 1.2 ms on a CPU without sacrificing the accuracy of a state-of-the-art two-stage detector on COCO and VOC datasets. Importantly, ASAP-NMS is agnostic to image resolution and can be used as a simple drop-in module during inference. Using ASAP-NMS at run-time only, we obtain an mAP of 44.2\%@25Hz on the COCO dataset with a V100 GPU.

Yunxi Xiong, Yuankai Huo, Jiachen Wang et al.

Whole brain segmentation on structural magnetic resonance imaging (MRI) is essential for understanding neuroanatomical-functional relationships. Traditionally, multi-atlas segmentation has been regarded as the standard method for whole brain segmentation. In past few years, deep convolutional neural network (DCNN) segmentation methods have demonstrated their advantages in both accuracy and computational efficiency. Recently, we proposed the spatially localized atlas network tiles (SLANT) method, which is able to segment a 3D MRI brain scan into 132 anatomical regions. Commonly, DCNN segmentation methods yield inferior performance under external validations, especially when the testing patterns were not presented in the training cohorts. Recently, we obtained a clinically acquired, multi-sequence MRI brain cohort with 1480 clinically acquired, de-identified brain MRI scans on 395 patients using seven different MRI protocols. Moreover, each subject has at least two scans from different MRI protocols. Herein, we assess the SLANT method's intra- and inter-protocol reproducibility. SLANT achieved less than 0.05 coefficient of variation (CV) for intra-protocol experiments and less than 0.15 CV for inter-protocol experiments. The results show that the SLANT method achieved high intra- and inter- protocol reproducibility.

Vishwesh Nath, Prasanna Parvathaneni, Colin B. Hansen et al.

Diffusion-weighted magnetic resonance imaging (DW-MRI) allows for non-invasive imaging of the local fiber architecture of the human brain at a millimetric scale. Multiple classical approaches have been proposed to detect both single (e.g., tensors) and multiple (e.g., constrained spherical deconvolution, CSD) fiber population orientations per voxel. However, existing techniques generally exhibit low reproducibility across MRI scanners. Herein, we propose a data-driven tech-nique using a neural network design which exploits two categories of data. First, training data were acquired on three squirrel monkey brains using ex-vivo DW-MRI and histology of the brain. Second, repeated scans of human subjects were acquired on two different scanners to augment the learning of the network pro-posed. To use these data, we propose a new network architecture, the null space deep network (NSDN), to simultaneously learn on traditional observed/truth pairs (e.g., MRI-histology voxels) along with repeated observations without a known truth (e.g., scan-rescan MRI). The NSDN was tested on twenty percent of the histology voxels that were kept completely blind to the network. NSDN significantly improved absolute performance relative to histology by 3.87% over CSD and 1.42% over a recently proposed deep neural network approach. More-over, it improved reproducibility on the paired data by 21.19% over CSD and 10.09% over a recently proposed deep approach. Finally, NSDN improved gen-eralizability of the model to a third in vivo human scanner (which was not used in training) by 16.08% over CSD and 10.41% over a recently proposed deep learn-ing approach. This work suggests that data-driven approaches for local fiber re-construction are more reproducible, informative and precise and offers a novel, practical method for determining these models.