Mingyi Jia

Zhihao Jia, Mingyi Jia, Junwen Duan et al.

Large Language Models (LLMs) demonstrate strong generalization and reasoning abilities, making them well-suited for complex decision-making tasks such as medical consultation (MC). However, existing LLM-based methods often fail to capture the dual nature of MC, which entails two distinct sub-tasks: symptom inquiry, a sequential decision-making process, and disease diagnosis, a classification problem. This mismatch often results in ineffective symptom inquiry and unreliable disease diagnosis. To address this, we propose \textbf{DDO}, a novel LLM-based framework that performs \textbf{D}ual-\textbf{D}ecision \textbf{O}ptimization by decoupling the two sub-tasks and optimizing them with distinct objectives through a collaborative multi-agent workflow. Experiments on three real-world MC datasets show that DDO consistently outperforms existing LLM-based approaches and achieves competitive performance with state-of-the-art generation-based methods, demonstrating its effectiveness in the MC task. The code is available at https://github.com/zh-jia/DDO.

Mingyi Jia, Junwen Duan, Yan Song et al.

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge Graphs as Assistants of LLMs), a framework that combines Large Language Models (LLMs) with knowledge graphs (KGs) to enhance diagnostic capabilities. medIKAL assigns weighted importance to entities in medical records based on their type, enabling precise localization of candidate diseases within KGs. It innovatively employs a residual network-like approach, allowing initial diagnosis by the LLM to be merged into KG search results. Through a path-based reranking algorithm and a fill-in-the-blank style prompt template, it further refined the diagnostic process. We validated medIKAL's effectiveness through extensive experiments on a newly introduced open-sourced Chinese EMR dataset, demonstrating its potential to improve clinical diagnosis in real-world settings.

Jiawei He, Mingyi Jia, Zhihao Jia et al.

Retrieval-Augmented Large Language Models (LLMs), which integrate external knowledge, have shown remarkable performance in medical domains, including clinical diagnosis. However, existing RAG methods often struggle to tailor retrieval strategies to diagnostic difficulty and input sample informativeness. This limitation leads to excessive and often unnecessary retrieval, impairing computational efficiency and increasing the risk of introducing noise that can degrade diagnostic accuracy. To address this, we propose ICA-RAG (\textbf{I}nformation \textbf{C}ompleteness Guided \textbf{A}daptive \textbf{R}etrieval-\textbf{A}ugmented \textbf{G}eneration), a novel framework for enhancing RAG reliability in disease diagnosis. ICA-RAG utilizes an adaptive control module to assess the necessity of retrieval based on the input's information completeness. By optimizing retrieval and incorporating knowledge filtering, ICA-RAG better aligns retrieval operations with clinical requirements. Experiments on three Chinese electronic medical record datasets demonstrate that ICA-RAG significantly outperforms baseline methods, highlighting its effectiveness in clinical diagnosis.