Jia Guo

Xiang An, Jiankang Deng, Jia Guo et al.

Learning discriminative deep feature embeddings by using million-scale in-the-wild datasets and margin-based softmax loss is the current state-of-the-art approach for face recognition. However, the memory and computing cost of the Fully Connected (FC) layer linearly scales up to the number of identities in the training set. Besides, the large-scale training data inevitably suffers from inter-class conflict and long-tailed distribution. In this paper, we propose a sparsely updating variant of the FC layer, named Partial FC (PFC). In each iteration, positive class centers and a random subset of negative class centers are selected to compute the margin-based softmax loss. All class centers are still maintained throughout the whole training process, but only a subset is selected and updated in each iteration. Therefore, the computing requirement, the probability of inter-class conflict, and the frequency of passive update on tail class centers, are dramatically reduced. Extensive experiments across different training data and backbones (e.g. CNN and ViT) confirm the effectiveness, robustness and efficiency of the proposed PFC. The source code is available at \https://github.com/deepinsight/insightface/tree/master/recognition.

Kaicheng Yang, Jiankang Deng, Xiang An et al.

Contrastive Language-Image Pre-training (CLIP) has significantly boosted the performance of various vision-language tasks by scaling up the dataset with image-text pairs collected from the web. However, the presence of intrinsic noise and unmatched image-text pairs in web data can potentially affect the performance of representation learning. To address this issue, we first utilize the OFA model to generate synthetic captions that focus on the image content. The generated captions contain complementary information that is beneficial for pre-training. Then, we propose an Adaptive Language-Image Pre-training (ALIP), a bi-path model that integrates supervision from both raw text and synthetic caption. As the core components of ALIP, the Language Consistency Gate (LCG) and Description Consistency Gate (DCG) dynamically adjust the weights of samples and image-text/caption pairs during the training process. Meanwhile, the adaptive contrastive loss can effectively reduce the impact of noise data and enhances the efficiency of pre-training data. We validate ALIP with experiments on different scales of models and pre-training datasets. Experiments results show that ALIP achieves state-of-the-art performance on multiple downstream tasks including zero-shot image-text retrieval and linear probe. To facilitate future research, the code and pre-trained models are released at https://github.com/deepglint/ALIP.

Xiang An, Jiankang Deng, Kaicheng Yang et al.

Modern image retrieval methods typically rely on fine-tuning pre-trained encoders to extract image-level descriptors. However, the most widely used models are pre-trained on ImageNet-1K with limited classes. The pre-trained feature representation is therefore not universal enough to generalize well to the diverse open-world classes. In this paper, we first cluster the large-scale LAION400M into one million pseudo classes based on the joint textual and visual features extracted by the CLIP model. Due to the confusion of label granularity, the automatically clustered dataset inevitably contains heavy inter-class conflict. To alleviate such conflict, we randomly select partial inter-class prototypes to construct the margin-based softmax loss. To further enhance the low-dimensional feature representation, we randomly select partial feature dimensions when calculating the similarities between embeddings and class-wise prototypes. The dual random partial selections are with respect to the class dimension and the feature dimension of the prototype matrix, making the classification conflict-robust and the feature embedding compact. Our method significantly outperforms state-of-the-art unsupervised and supervised image retrieval approaches on multiple benchmarks. The code and pre-trained models are released to facilitate future research https://github.com/deepglint/unicom.

Xuzhe Zhang, Yuhao Wu, Elsa Angelini et al.

Robust segmentation is critical for deriving quantitative measures from large-scale, multi-center, and longitudinal medical scans. Manually annotating medical scans, however, is expensive and labor-intensive and may not always be available in every domain. Unsupervised domain adaptation (UDA) is a well-studied technique that alleviates this label-scarcity problem by leveraging available labels from another domain. In this study, we introduce Masked Autoencoding and Pseudo-Labeling Segmentation (MAPSeg), a $\textbf{unified}$ UDA framework with great versatility and superior performance for heterogeneous and volumetric medical image segmentation. To the best of our knowledge, this is the first study that systematically reviews and develops a framework to tackle four different domain shifts in medical image segmentation. More importantly, MAPSeg is the first framework that can be applied to $\textbf{centralized}$, $\textbf{federated}$, and $\textbf{test-time}$ UDA while maintaining comparable performance. We compare MAPSeg with previous state-of-the-art methods on a private infant brain MRI dataset and a public cardiac CT-MRI dataset, and MAPSeg outperforms others by a large margin (10.5 Dice improvement on the private MRI dataset and 5.7 on the public CT-MRI dataset). MAPSeg poses great practical value and can be applied to real-world problems. GitHub: https://github.com/XuzheZ/MAPSeg/.

Jee Seok Yoon, Chenghao Zhang, Heung-Il Suk et al.

Human organs constantly undergo anatomical changes due to a complex mix of short-term (e.g., heartbeat) and long-term (e.g., aging) factors. Evidently, prior knowledge of these factors will be beneficial when modeling their future state, i.e., via image generation. However, most of the medical image generation tasks only rely on the input from a single image, thus ignoring the sequential dependency even when longitudinal data is available. Sequence-aware deep generative models, where model input is a sequence of ordered and timestamped images, are still underexplored in the medical imaging domain that is featured by several unique challenges: 1) Sequences with various lengths; 2) Missing data or frame, and 3) High dimensionality. To this end, we propose a sequence-aware diffusion model (SADM) for the generation of longitudinal medical images. Recently, diffusion models have shown promising results in high-fidelity image generation. Our method extends this new technique by introducing a sequence-aware transformer as the conditional module in a diffusion model. The novel design enables learning longitudinal dependency even with missing data during training and allows autoregressive generation of a sequence of images during inference. Our extensive experiments on 3D longitudinal medical images demonstrate the effectiveness of SADM compared with baselines and alternative methods. The code is available at https://github.com/ubc-tea/SADM-Longitudinal-Medical-Image-Generation.

Evangelos Ververas, Polydefkis Gkagkos, Jiankang Deng et al.

Developing gaze estimation models that generalize well to unseen domains and in-the-wild conditions remains a challenge with no known best solution. This is mostly due to the difficulty of acquiring ground truth data that cover the distribution of faces, head poses, and environments that exist in the real world. Most recent methods attempt to close the gap between specific source and target domains using domain adaptation. In this work, we propose to train general gaze estimation models which can be directly employed in novel environments without adaptation. To do so, we leverage the observation that head, body, and hand pose estimation benefit from revising them as dense 3D coordinate prediction, and similarly express gaze estimation as regression of dense 3D eye meshes. To close the gap between image domains, we create a large-scale dataset of diverse faces with gaze pseudo-annotations, which we extract based on the 3D geometry of the scene, and design a multi-view supervision framework to balance their effect during training. We test our method in the task of gaze generalization, in which we demonstrate improvement of up to 30% compared to state-of-the-art when no ground truth data are available, and up to 10% when they are. The project material are available for research purposes at https://github.com/Vagver/3DGazeNet.

Shengzhu Yang, Jiawei Du, Jia Guo et al.

Subtle semantic differences in retinal image and text data present great challenges for pre-training visual-language models. Moreover, false negative samples, i.e., image-text pairs having the same semantics but incorrectly regarded as negatives, disrupt the visual-language pre-training process and affect the model's learning ability. This work aims to develop a retinal foundation model, called ViLReF, by pre-training on a paired dataset comprising 451,956 retinal images and corresponding diagnostic text reports. In our vision-language pre-training strategy, we leverage expert knowledge to facilitate the extraction of labels and propose a novel constraint, the Weighted Similarity Coupling Loss, to adjust the speed of pushing sample pairs further apart dynamically within the feature space. Furthermore, we employ a batch expansion module with dynamic memory queues, maintained by momentum encoders, to supply extra samples and compensate for the vacancies caused by eliminating false negatives. Extensive experiments are conducted on multiple datasets for downstream classification and segmentation tasks. The experimental results demonstrate the powerful zero-shot and transfer learning capabilities of ViLReF, verifying the effectiveness of our pre-training strategy. Our ViLReF model is available at: https://github.com/T6Yang/ViLReF.

Junhao Zhang, Vishwanatha M. Rao, Ye Tian et al.

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and improve classification and diagnostic accuracy. We tested this hypothesis using a single, widely available, and conventional T1-weighted MRI scan, from which we extracted the 3D whole-brain structure using standard post-processing methods. A deep learning model was then developed, optimized, and evaluated on three open datasets with T1-weighted MRI scans of patients with schizophrenia. Our proposed model outperformed the benchmark model, which was also trained with structural MR images using a 3D CNN architecture. Our model is capable of almost perfectly (area under the ROC curve = 0.987) distinguishing schizophrenia patients from healthy controls on unseen structural MRI scans. Regional analysis localized subcortical regions and ventricles as the most predictive brain regions. Subcortical structures serve a pivotal role in cognitive, affective, and social functions in humans, and structural abnormalities of these regions have been associated with schizophrenia. Our finding corroborates that schizophrenia is associated with widespread alterations in subcortical brain structure and the subcortical structural information provides prominent features in diagnostic classification. Together, these results further demonstrate the potential of deep learning to improve schizophrenia diagnosis and identify its structural neuroimaging signatures from a single, standard T1-weighted brain MRI.

Dong Wang, Jia Guo, Qiqi Shao et al.

Face anti-spoofing (FAS) is an essential mechanism for safeguarding the integrity of automated face recognition systems. Despite substantial advancements, the generalization of existing approaches to real-world applications remains challenging. This limitation can be attributed to the scarcity and lack of diversity in publicly available FAS datasets, which often leads to overfitting during training or saturation during testing. In terms of quantity, the number of spoof subjects is a critical determinant. Most datasets comprise fewer than 2,000 subjects. With regard to diversity, the majority of datasets consist of spoof samples collected in controlled environments using repetitive, mechanical processes. This data collection methodology results in homogenized samples and a dearth of scenario diversity. To address these shortcomings, we introduce the Wild Face Anti-Spoofing (WFAS) dataset, a large-scale, diverse FAS dataset collected in unconstrained settings. Our dataset encompasses 853,729 images of 321,751 spoof subjects and 529,571 images of 148,169 live subjects, representing a substantial increase in quantity. Moreover, our dataset incorporates spoof data obtained from the internet, spanning a wide array of scenarios and various commercial sensors, including 17 presentation attacks (PAs) that encompass both 2D and 3D forms. This novel data collection strategy markedly enhances FAS data diversity. Leveraging the WFAS dataset and Protocol 1 (Known-Type), we host the Wild Face Anti-Spoofing Challenge at the CVPR2023 workshop. Additionally, we meticulously evaluate representative methods using Protocol 1 and Protocol 2 (Unknown-Type). Through an in-depth examination of the challenge outcomes and benchmark baselines, we provide insightful analyses and propose potential avenues for future research. The dataset is released under Insightface.

Gongning Luo, Kuanquan Wang, Jun Liu et al.

Efficient automatic segmentation of multi-level (i.e. main and branch) pulmonary arteries (PA) in CTPA images plays a significant role in clinical applications. However, most existing methods concentrate only on main PA or branch PA segmentation separately and ignore segmentation efficiency. Besides, there is no public large-scale dataset focused on PA segmentation, which makes it highly challenging to compare the different methods. To benchmark multi-level PA segmentation algorithms, we organized the first \textbf{P}ulmonary \textbf{AR}tery \textbf{SE}gmentation (PARSE) challenge. On the one hand, we focus on both the main PA and the branch PA segmentation. On the other hand, for better clinical application, we assign the same score weight to segmentation efficiency (mainly running time and GPU memory consumption during inference) while ensuring PA segmentation accuracy. We present a summary of the top algorithms and offer some suggestions for efficient and accurate multi-level PA automatic segmentation. We provide the PARSE challenge as open-access for the community to benchmark future algorithm developments at \url{https://parse2022.grand-challenge.org/Parse2022/}.

Yao Peng, Jia Guo, Chenyang Yang

Graph neural networks (GNNs) update the hidden representations of vertices (called Vertex-GNNs) or hidden representations of edges (called Edge-GNNs) by processing and pooling the information of neighboring vertices and edges and combining to exploit topology information. When learning resource allocation policies, GNNs cannot perform well if their expressive power is weak, i.e., if they cannot differentiate all input features such as channel matrices. In this paper, we analyze the expressive power of the Vertex-GNNs and Edge-GNNs for learning three representative wireless policies: link scheduling, power control, and precoding policies. We find that the expressive power of the GNNs depends on the linearity and output dimensions of the processing and combination functions. When linear processors are used, the Vertex-GNNs cannot differentiate all channel matrices due to the loss of channel information, while the Edge-GNNs can. When learning the precoding policy, even the Vertex-GNNs with non-linear processors may not be with strong expressive ability due to the dimension compression. We proceed to provide necessary conditions for the GNNs to well learn the precoding policy. Simulation results validate the analyses and show that the Edge-GNNs can achieve the same performance as the Vertex-GNNs with much lower training and inference time.

Jia Guo, Stanley Kok, Lidong Bing

Document-level relation extraction (DocRE) predicts relations for entity pairs that rely on long-range context-dependent reasoning in a document. As a typical multi-label classification problem, DocRE faces the challenge of effectively distinguishing a small set of positive relations from the majority of negative ones. This challenge becomes even more difficult to overcome when there exists a significant number of annotation errors in the dataset. In this work, we aim to achieve better integration of both the discriminability and robustness for the DocRE problem. Specifically, we first design an effective loss function to endow high discriminability to both probabilistic outputs and internal representations. We innovatively customize entropy minimization and supervised contrastive learning for the challenging multi-label and long-tailed learning problems. To ameliorate the impact of label errors, we equipped our method with a novel negative label sampling strategy to strengthen the model robustness. In addition, we introduce two new data regimes to mimic more realistic scenarios with annotation errors and evaluate our sampling strategy. Experimental results verify the effectiveness of each component and show that our method achieves new state-of-the-art results on the DocRED dataset, its recently cleaned version, Re-DocRED, and the proposed data regimes.

Jia Guo, Chenyang Yang

Learning precoding policies with neural networks enables low complexity online implementation, robustness to channel impairments, and joint optimization with channel acquisition. However, existing neural networks suffer from high training complexity and poor generalization ability when they are used to learn to optimize precoding for mitigating multi-user interference. This impedes their use in practical systems where the number of users is time-varying. In this paper, we propose a graph neural network (GNN) to learn precoding policies by harnessing both the mathematical model and the property of the policies. We first show that a vanilla GNN cannot well-learn pseudo-inverse of channel matrix when the numbers of antennas and users are large, and is not generalizable to unseen numbers of users. Then, we design a GNN by resorting to the Taylor's expansion of matrix pseudo-inverse, which allows for capturing the importance of the neighbored edges to be aggregated that is crucial for learning precoding policies efficiently. Simulation results show that the proposed GNN can well learn spectral efficient and energy efficient precoding policies in single- and multi-cell multi-user multi-antenna systems with low training complexity, and can be well generalized to the numbers of users.

Ramy Hussein, David Shin, Moss Zhao et al.

Accurate quantification of cerebral blood flow (CBF) is essential for the diagnosis and assessment of a wide range of neurological diseases. Positron emission tomography (PET) with radiolabeled water (15O-water) is considered the gold-standard for the measurement of CBF in humans. PET imaging, however, is not widely available because of its prohibitive costs and use of short-lived radiopharmaceutical tracers that typically require onsite cyclotron production. Magnetic resonance imaging (MRI), in contrast, is more readily accessible and does not involve ionizing radiation. This study presents a convolutional encoder-decoder network with attention mechanisms to predict gold-standard 15O-water PET CBF from multi-sequence MRI scans, thereby eliminating the need for radioactive tracers. Inputs to the prediction model include several commonly used MRI sequences (T1-weighted, T2-FLAIR, and arterial spin labeling). The model was trained and validated using 5-fold cross-validation in a group of 126 subjects consisting of healthy controls and cerebrovascular disease patients, all of whom underwent simultaneous $15O-water PET/MRI. The results show that such a model can successfully synthesize high-quality PET CBF measurements (with an average SSIM of 0.924 and PSNR of 38.8 dB) and is more accurate compared to concurrent and previous PET synthesis methods. We also demonstrate the clinical significance of the proposed algorithm by evaluating the agreement for identifying the vascular territories with abnormally low CBF. Such methods may enable more widespread and accurate CBF evaluation in larger cohorts who cannot undergo PET imaging due to radiation concerns, lack of access, or logistic challenges.

Zhuhao Wang, Fang Chen, Chaohui Yu et al.

CT interpretation requires radiologists to review hundreds of volumetric slices per examination, making reporting time-consuming and highly expertise-dependent. Automated CT report generation offers a promising route to improving clinical efficiency, yet the field still lacks a generalizable CT report generation foundation model that supports multi-region reporting and remains robust across external real-world cohorts. Intrinsic inconsistencies in reporting style and diagnostic terminology across cohorts make naive joint training prone to noisy textual supervision, thereby limiting model generalizability. Here we present Astra, a generalizable CT report generation foundation model trained on 90,678 thoracoabdominal CT-report pairs (CTRgDB) with 353,671 abnormalities spanning eight organ systems. By harmonizing report style and further refining diagnostic consistency via reinforcement learning, Astra achieves style-consistent and diagnostically accurate report generation across diverse anatomical regions and institutions. Evaluating on CTRgDB and six external cohorts, Astra achieves state-of-the-art performance with a 44.1% average improvement in fine-grained diagnostic metrics (P<0.001). In real-world clinical workflows, Astra assistance accelerates chest report drafting by 29.6% and improves abdominal report completeness by 11.3% (P<0.001). Furthermore, Astra also demonstrates broad utility as a foundation for CT AI development, improving downstream diagnostic performance and scaling vision-language pretrain through high-quality report synthesis. Overall, Astra serves as a broadly accessible clinical assistant and a pivotal infrastructure for the next generation of AI-powered healthcare.

Jia Guo, Shuai Lu, Lize Jia et al.

Most advanced unsupervised anomaly detection (UAD) methods rely on modeling feature representations of frozen encoder networks pre-trained on large-scale datasets, e.g. ImageNet. However, the features extracted from the encoders that are borrowed from natural image domains coincide little with the features required in the target UAD domain, such as industrial inspection and medical imaging. In this paper, we propose a novel epistemic UAD method, namely ReContrast, which optimizes the entire network to reduce biases towards the pre-trained image domain and orients the network in the target domain. We start with a feature reconstruction approach that detects anomalies from errors. Essentially, the elements of contrastive learning are elegantly embedded in feature reconstruction to prevent the network from training instability, pattern collapse, and identical shortcut, while simultaneously optimizing both the encoder and decoder on the target domain. To demonstrate our transfer ability on various image domains, we conduct extensive experiments across two popular industrial defect detection benchmarks and three medical image UAD tasks, which shows our superiority over current state-of-the-art methods.

Jia Guo, Haifeng Wang, Chenping Hou

Physics-Informed Neural Networks (PINNs) have become a kind of attractive machine learning method for obtaining solutions of partial differential equations (PDEs). Training PINNs can be seen as a semi-supervised learning task, in which only exact values of initial and boundary points can be obtained in solving forward problems, and in the whole spatio-temporal domain collocation points are sampled without exact labels, which brings training difficulties. Thus the selection of collocation points and sampling methods are quite crucial in training PINNs. Existing sampling methods include fixed and dynamic types, and in the more popular latter one, sampling is usually controlled by PDE residual loss. We point out that it is not sufficient to only consider the residual loss in adaptive sampling and sampling should obey temporal causality. We further introduce temporal causality into adaptive sampling and propose a novel adaptive causal sampling method to improve the performance and efficiency of PINNs. Numerical experiments of several PDEs with high-order derivatives and strong nonlinearity, including Cahn Hilliard and KdV equations, show that the proposed sampling method can improve the performance of PINNs with few collocation points. We demonstrate that by utilizing such a relatively simple sampling method, prediction performance can be improved up to two orders of magnitude compared with state-of-the-art results with almost no extra computation cost, especially when points are limited.

Jinli Liao, Yikang Ding, Yoli Shavit et al.

Recently, Transformers were shown to enhance the performance of multi-view stereo by enabling long-range feature interaction. In this work, we propose Window-based Transformers (WT) for local feature matching and global feature aggregation in multi-view stereo. We introduce a Window-based Epipolar Transformer (WET) which reduces matching redundancy by using epipolar constraints. Since point-to-line matching is sensitive to erroneous camera pose and calibration, we match windows near the epipolar lines. A second Shifted WT is employed for aggregating global information within cost volume. We present a novel Cost Transformer (CT) to replace 3D convolutions for cost volume regularization. In order to better constrain the estimated depth maps from multiple views, we further design a novel geometric consistency loss (Geo Loss) which punishes unreliable areas where multi-view consistency is not satisfied. Our WT multi-view stereo method (WT-MVSNet) achieves state-of-the-art performance across multiple datasets and ranks $1^{st}$ on Tanks and Temples benchmark.

Aaron Cao, Zongyu Li, Jordan Jomsky et al.

Widely used traditional pipelines for subcortical brain segmentation are often inefficient and slow, particularly when processing large datasets. Furthermore, deep learning models face challenges due to the high resolution of MRI images and the large number of anatomical classes involved. To address these limitations, we developed a 3D patch-based hybrid CNN-Mamba model that leverages Mamba's selective scan algorithm, thereby enhancing segmentation accuracy and efficiency for 3D inputs. This retrospective study utilized 1784 T1-weighted MRI scans from a diverse, multi-site dataset of healthy individuals. The dataset was divided into training, validation, and testing sets with a 1076/345/363 split. The scans were obtained from 1.5T and 3T MRI machines. Our model's performance was validated against several benchmarks, including other CNN-Mamba, CNN-Transformer, and pure CNN networks, using FreeSurfer-generated ground truths. We employed the Dice Similarity Coefficient (DSC), Volume Similarity (VS), and Average Symmetric Surface Distance (ASSD) as evaluation metrics. Statistical significance was determined using the Wilcoxon signed-rank test with a threshold of P < 0.05. The proposed model achieved the highest overall performance across all metrics (DSC 0.88383; VS 0.97076; ASSD 0.33604), significantly outperforming all non-Mamba-based models (P < 0.001). While the model did not show significant improvement in DSC or VS compared to another Mamba-based model (P-values of 0.114 and 0.425), it demonstrated a significant enhancement in ASSD (P < 0.001) with approximately 20% fewer parameters. In conclusion, our proposed hybrid CNN-Mamba architecture offers an efficient and accurate approach for 3D subcortical brain segmentation, demonstrating potential advantages over existing methods. Code is available at: https://github.com/aaroncao06/MedSegMamba.

Nathan Powell, Bowei Liu, Jia Guo et al.

This paper introduces a data-dependent approximation of the forward kinematics map for certain types of animal motion models. It is assumed that motions are supported on a low-dimensional, unknown configuration manifold $Q$ that is regularly embedded in high dimensional Euclidean space $X:=\mathbb{R}^d$. This paper introduces a method to estimate forward kinematics from the unknown configuration submanifold $Q$ to an $n$-dimensional Euclidean space $Y:=\mathbb{R}^n$ of observations. A known reproducing kernel Hilbert space (RKHS) is defined over the ambient space $X$ in terms of a known kernel function, and computations are performed using the known kernel defined on the ambient space $X$. Estimates are constructed using a certain data-dependent approximation of the Koopman operator defined in terms of the known kernel on $X$. However, the rate of convergence of approximations is studied in the space of restrictions to the unknown manifold $Q$. Strong rates of convergence are derived in terms of the fill distance of samples in the unknown configuration manifold, provided that a novel regularity result holds for the Koopman operator. Additionally, we show that the derived rates of convergence can be applied in some cases to estimates generated by the extended dynamic mode decomposition (EDMD) method. We illustrate characteristics of the estimates for simulated data as well as samples collected during motion capture experiments.

Jia Guo, Jiawei Du, Shengzhu Yang et al.

Current retinal foundation models remain constrained by curated research datasets that lack authentic clinical context, and require extensive task-specific optimization for each application, limiting their deployment efficiency in low-resource settings. Here, we show that these barriers can be overcome by building clinical native intelligence directly from real-world medical practice. Our key insight is that large-scale telemedicine programs, where expert centers provide remote consultations across distributed facilities, represent a natural reservoir for learning clinical image interpretation. We present ReVision, a retinal foundation model that learns from the natural alignment between 485,980 color fundus photographs and their corresponding diagnostic reports, accumulated through a decade-long telemedicine program spanning 162 medical institutions across China. Through extensive evaluation across 27 ophthalmic benchmarks, we demonstrate that ReVison enables deployment efficiency with minimal local resources. Without any task-specific training, ReVision achieves zero-shot disease detection with an average AUROC of 0.946 across 12 public benchmarks and 0.952 on 3 independent clinical cohorts. When minimal adaptation is feasible, ReVision matches extensively fine-tuned alternatives while requiring orders of magnitude fewer trainable parameters and labeled examples. The learned representations also transfer effectively to new clinical sites, imaging domains, imaging modalities, and systemic health prediction tasks. In a prospective reader study with 33 ophthalmologists, ReVision's zero-shot assistance improved diagnostic accuracy by 14.8% across all experience levels. These results demonstrate that clinical native intelligence can be directly extracted from clinical archives without any further annotation to build medical AI systems suited to various low-resource settings.

Jia Guo, Jinke Yu, Alexandros Lattas et al.

Even though 3D face reconstruction has achieved impressive progress, most orthogonal projection-based face reconstruction methods can not achieve accurate and consistent reconstruction results when the face is very close to the camera due to the distortion under the perspective projection. In this paper, we propose to simultaneously reconstruct 3D face mesh in the world space and predict 2D face landmarks on the image plane to address the problem of perspective 3D face reconstruction. Based on the predicted 3D vertices and 2D landmarks, the 6DoF (6 Degrees of Freedom) face pose can be easily estimated by the PnP solver to represent perspective projection. Our approach achieves 1st place on the leader-board of the ECCV 2022 WCPA challenge and our model is visually robust under different identities, expressions and poses. The training code and models are released to facilitate future research.

Jiawei Du, Jia Guo, Weihang Zhang et al.

The Vision-Language Foundation model is increasingly investigated in the fields of computer vision and natural language processing, yet its exploration in ophthalmology and broader medical applications remains limited. The challenge is the lack of labeled data for the training of foundation model. To handle this issue, a CLIP-style retinal image foundation model is developed in this paper. Our foundation model, RET-CLIP, is specifically trained on a dataset of 193,865 patients to extract general features of color fundus photographs (CFPs), employing a tripartite optimization strategy to focus on left eye, right eye, and patient level to reflect real-world clinical scenarios. Extensive experiments demonstrate that RET-CLIP outperforms existing benchmarks across eight diverse datasets spanning four critical diagnostic categories: diabetic retinopathy, glaucoma, multiple disease diagnosis, and multi-label classification of multiple diseases, which demonstrate the performance and generality of our foundation model. The sourse code and pre-trained model are available at https://github.com/sStonemason/RET-CLIP.

Longxu Dou, Qian Liu, Guangtao Zeng et al.

We present Sailor, a family of open language models ranging from 0.5B to 7B parameters, tailored for South-East Asian (SEA) languages. These models are continually pre-trained from Qwen1.5, a great language model for multilingual use cases. From Qwen1.5, Sailor models accept 200B to 400B tokens, primarily covering the languages of English, Chinese, Vietnamese, Thai, Indonesian, Malay, and Lao. The training leverages several techniques, including BPE dropout for improving the model robustness, aggressive data cleaning and deduplication, and small proxy models to optimize data mixture. Experimental results on four typical tasks indicate that Sailor models demonstrate strong performance across different benchmarks, including commonsense reasoning, question answering, reading comprehension and examination. Embracing the open-source spirit, we share our insights through this report to spark a wider interest in developing large language models for multilingual use cases.

Zhuoyao Xin, Yiren Zhang, Christopher Wu et al.

Accurate synthesis of computed tomography (CT) images from magnetic resonance imaging (MRI) is clinically valuable for cranial applications such as attenuation correction, radiotherapy planning, and image-guided interventions. However, heterogeneity across MRI field strengths and acquisition protocols limits the generalizability of existing methods. In this study, we formulate cranial CT synthesis as a modular, structurally coupled problem and propose a deep learning framework to improve robustness across heterogeneous MRI conditions. The model is designed to adapt to variations in field strength and imaging protocols while preserving anatomical consistency. Experiments on multi-site datasets demonstrate improved performance and generalization compared with conventional approaches. The proposed method enables reliable CT synthesis across heterogeneous MRI settings, supporting broader clinical translation.

Qishan Wang, Haofeng Wang, Shuyong Gao et al.

Industrial anomaly detection is a challenging open-set task that aims to identify unknown anomalous patterns deviating from normal data distribution. To avoid the significant memory consumption and limited generalizability brought by building separate models per class, we focus on developing a unified framework for multi-class anomaly detection. However, under this challenging setting, conventional reconstruction-based networks often suffer from an identity mapping problem, where they directly replicate input features regardless of whether they are normal or anomalous, resulting in detection failures. To address this issue, this study proposes a novel framework termed Collaborative Reconstruction and Repair (CRR), which transforms the reconstruction to repairation. First, we optimize the decoder to reconstruct normal samples while repairing synthesized anomalies. Consequently, it generates distinct representations for anomalous regions and similar representations for normal areas compared to the encoder's output. Second, we implement feature-level random masking to ensure that the representations from decoder contain sufficient local information. Finally, to minimize detection errors arising from the discrepancies between feature representations from the encoder and decoder, we train a segmentation network supervised by synthetic anomaly masks, thereby enhancing localization performance. Extensive experiments on industrial datasets that CRR effectively mitigates the identity mapping issue and achieves state-of-the-art performance in multi-class industrial anomaly detection.

Christopher J. Wu, Lawrence S. Kegeles, Jia Guo

Magnetic resonance spectroscopy (MRS) is an established technique for studying tissue metabolism, particularly in central nervous system disorders. While powerful and versatile, MRS is often limited by challenges associated with data quality, processing, and quantification. Existing MRS quantification methods face difficulties in balancing model complexity and reproducibility during spectral modeling, often falling into the trap of either oversimplification or over-parameterization. To address these limitations, this study introduces a deep learning (DL) framework that employs transfer learning, in which the model is pre-trained on simulated datasets before it undergoes fine-tuning on in vivo data. The proposed framework showed promising performance when applied to the Philips dataset from the BIG GABA repository and represents an exciting advancement in MRS data analysis.

Ling Team, Anqi Shen, Baihui Li et al.

We present Ring-1T, the first open-source, state-of-the-art thinking model with a trillion-scale parameter. It features 1 trillion total parameters and activates approximately 50 billion per token. Training such models at a trillion-parameter scale introduces unprecedented challenges, including train-inference misalignment, inefficiencies in rollout processing, and bottlenecks in the RL system. To address these, we pioneer three interconnected innovations: (1) IcePop stabilizes RL training via token-level discrepancy masking and clipping, resolving instability from training-inference mismatches; (2) C3PO++ improves resource utilization for long rollouts under a token budget by dynamically partitioning them, thereby obtaining high time efficiency; and (3) ASystem, a high-performance RL framework designed to overcome the systemic bottlenecks that impede trillion-parameter model training. Ring-1T delivers breakthrough results across critical benchmarks: 93.4 on AIME-2025, 86.72 on HMMT-2025, 2088 on CodeForces, and 55.94 on ARC-AGI-1. Notably, it attains a silver medal-level result on the IMO-2025, underscoring its exceptional reasoning capabilities. By releasing the complete 1T parameter MoE model to the community, we provide the research community with direct access to cutting-edge reasoning capabilities. This contribution marks a significant milestone in democratizing large-scale reasoning intelligence and establishes a new baseline for open-source model performance.

Ling Team, Caizhi Tang, Chilin Fu et al.

This technical report presents Ring-Lite-Distill, a lightweight reasoning model derived from our open-source Mixture-of-Experts (MoE) Large Language Models (LLMs) Ling-Lite. This study demonstrates that through meticulous high-quality data curation and ingenious training paradigms, the compact MoE model Ling-Lite can be further trained to achieve exceptional reasoning capabilities, while maintaining its parameter-efficient architecture with only 2.75 billion activated parameters, establishing an efficient lightweight reasoning architecture. In particular, in constructing this model, we have not merely focused on enhancing advanced reasoning capabilities, exemplified by high-difficulty mathematical problem solving, but rather aimed to develop a reasoning model with more comprehensive competency coverage. Our approach ensures coverage across reasoning tasks of varying difficulty levels while preserving generic capabilities, such as instruction following, tool use, and knowledge retention. We show that, Ring-Lite-Distill's reasoning ability reaches a level comparable to DeepSeek-R1-Distill-Qwen-7B, while its general capabilities significantly surpass those of DeepSeek-R1-Distill-Qwen-7B. The models are accessible at https://huggingface.co/inclusionAI

Yanting Yang, Yiren Zhang, Zongyu Li et al.

Deep complex-valued neural networks (CVNNs) provide a powerful way to leverage complex number operations and representations and have succeeded in several phase-based applications. However, previous networks have not fully explored the impact of complex-valued networks in the frequency domain. Here, we introduce a unified complex-valued deep learning framework-Artificial Fourier Transform Network (AFTNet)-which combines domain-manifold learning and CVNNs. AFTNet can be readily used to solve image inverse problems in domain transformation, especially for accelerated magnetic resonance imaging (MRI) reconstruction and other applications. While conventional methods typically utilize magnitude images or treat the real and imaginary components of k-space data as separate channels, our approach directly processes raw k-space data in the frequency domain, utilizing complex-valued operations. This allows for a mapping between the frequency (k-space) and image domain to be determined through cross-domain learning. We show that AFTNet achieves superior accelerated MRI reconstruction compared to existing approaches. Furthermore, our approach can be applied to various tasks, such as denoised magnetic resonance spectroscopy (MRS) reconstruction and datasets with various contrasts. The AFTNet presented here is a valuable preprocessing component for different preclinical studies and provides an innovative alternative for solving inverse problems in imaging and spectroscopy. The code is available at: https://github.com/yanting-yang/AFT-Net.

Qishan Wang, Jia Guo, Shuyong Gao et al.

Few-shot anomaly detection (FSAD) has emerged as a crucial yet challenging task in industrial inspection, where normal distribution modeling must be accomplished with only a few normal images. While existing approaches typically employ multi-modal foundation models combining language and vision modalities for prompt-guided anomaly detection, these methods often demand sophisticated prompt engineering and extensive manual tuning. In this paper, we demonstrate that a straightforward nearest-neighbor search framework can surpass state-of-the-art performance in both single-class and multi-class FSAD scenarios. Our proposed method, VisionAD, consists of four simple yet essential components: (1) scalable vision foundation models that extract universal and discriminative features; (2) dual augmentation strategies - support augmentation to enhance feature matching adaptability and query augmentation to address the oversights of single-view prediction; (3) multi-layer feature integration that captures both low-frequency global context and high-frequency local details with minimal computational overhead; and (4) a class-aware visual memory bank enabling efficient one-for-all multi-class detection. Extensive evaluations across MVTec-AD, VisA, and Real-IAD benchmarks demonstrate VisionAD's exceptional performance. Using only 1 normal images as support, our method achieves remarkable image-level AUROC scores of 97.4%, 94.8%, and 70.8% respectively, outperforming current state-of-the-art approaches by significant margins (+1.6%, +3.2%, and +1.4%). The training-free nature and superior few-shot capabilities of VisionAD make it particularly appealing for real-world applications where samples are scarce or expensive to obtain. Code is available at https://github.com/Qiqigeww/VisionAD.

Jinglue Xu, Jialong Li, Zhen Liu et al.

Recently, program synthesis driven by large language models (LLMs) has become increasingly popular. However, program synthesis for machine learning (ML) tasks still poses significant challenges. This paper explores a novel form of program synthesis, targeting ML programs, by combining LLMs and automated machine learning (autoML). Specifically, our goal is to fully automate the generation and optimization of the code of the entire ML workflow, from data preparation to modeling and post-processing, utilizing only textual descriptions of the ML tasks. To manage the length and diversity of ML programs, we propose to break each ML program into smaller, manageable parts. Each part is generated separately by the LLM, with careful consideration of their compatibilities. To ensure compatibilities, we design a testing technique for ML programs. Unlike traditional program synthesis, which typically relies on binary evaluations (i.e., correct or incorrect), evaluating ML programs necessitates more than just binary judgments. Our approach automates the numerical evaluation and optimization of these programs, selecting the best candidates through autoML techniques. In experiments across various ML tasks, our method outperforms existing methods in 10 out of 12 tasks for generating ML programs. In addition, autoML significantly improves the performance of the generated ML programs. In experiments, given the textual task description, our method, Text-to-ML, generates the complete and optimized ML program in a fully autonomous process. The implementation of our method is available at https://github.com/JLX0/llm-automl.

Vishwanatha M. Rao, Zihan Wan, Soroush Arabshahi et al.

Brain tissue segmentation has demonstrated great utility in quantifying MRI data through Voxel-Based Morphometry and highlighting subtle structural changes associated with various conditions within the brain. However, manual segmentation is highly labor-intensive, and automated approaches have struggled due to properties inherent to MRI acquisition, leaving a great need for an effective segmentation tool. Despite the recent success of deep convolutional neural networks (CNNs) for brain tissue segmentation, many such solutions do not generalize well to new datasets, which is critical for a reliable solution. Transformers have demonstrated success in natural image segmentation and have recently been applied to 3D medical image segmentation tasks due to their ability to capture long-distance relationships in the input where the local receptive fields of CNNs struggle. This study introduces a novel CNN-Transformer hybrid architecture designed for brain tissue segmentation. We validate our model's performance across four multi-site T1w MRI datasets, covering different vendors, field strengths, scan parameters, time points, and neuropsychiatric conditions. In all situations, our model achieved the greatest generality and reliability. Out method is inherently robust and can serve as a valuable tool for brain-related T1w MRI studies. The code for the TABS network is available at: https://github.com/raovish6/TABS.

Jia Guo, Minghao Chen, Yao Hu et al.

Knowledge distillation aims at obtaining a compact and effective model by learning the mapping function from a much larger one. Due to the limited capacity of the student, the student would underfit the teacher. Therefore, student performance would unexpectedly drop when distilling from an oversized teacher, termed the capacity gap problem. We investigate this problem by study the gap of confidence between teacher and student. We find that the magnitude of confidence is not necessary for knowledge distillation and could harm the student performance if the student are forced to learn confidence. We propose Spherical Knowledge Distillation to eliminate this gap explicitly, which eases the underfitting problem. We find this novel knowledge representation can improve compact models with much larger teachers and is robust to temperature. We conducted experiments on both CIFAR100 and ImageNet, and achieve significant improvement. Specifically, we train ResNet18 to 73.0 accuracy, which is a substantial improvement over previous SOTA and is on par with resnet34 almost twice the student size. The implementation has been shared at https://github.com/forjiuzhou/Spherical-Knowledge-Distillation.

Jiankang Deng, Jia Guo, Yuxiang Zhou et al.

Though tremendous strides have been made in uncontrolled face detection, accurate and efficient face localisation in the wild remains an open challenge. This paper presents a robust single-stage face detector, named RetinaFace, which performs pixel-wise face localisation on various scales of faces by taking advantages of joint extra-supervised and self-supervised multi-task learning. Specifically, We make contributions in the following five aspects: (1) We manually annotate five facial landmarks on the WIDER FACE dataset and observe significant improvement in hard face detection with the assistance of this extra supervision signal. (2) We further add a self-supervised mesh decoder branch for predicting a pixel-wise 3D shape face information in parallel with the existing supervised branches. (3) On the WIDER FACE hard test set, RetinaFace outperforms the state of the art average precision (AP) by 1.1% (achieving AP equal to 91.4%). (4) On the IJB-C test set, RetinaFace enables state of the art methods (ArcFace) to improve their results in face verification (TAR=89.59% for FAR=1e-6). (5) By employing light-weight backbone networks, RetinaFace can run real-time on a single CPU core for a VGA-resolution image. Extra annotations and code have been made available at: https://github.com/deepinsight/insightface/tree/master/RetinaFace.

Yan Sun, Jia Guo, Stanley Kok et al.

Reinforcement learning with verifiable rewards (RLVR) has improved the reasoning ability of large language models, yet training remains costly because many rollouts contribute little to optimization, considering the amount of computation required. This study investigates how simply leveraging intrinsic data properties, almost free benefit during training, can improve data efficiency for RLVR. We propose PREPO with two complementary components. First, we adopt prompt perplexity as an indicator of model adaptability in learning, enabling the model to progress from well-understood contexts to more challenging ones. Second, we amplify the discrepancy among the rollouts by differentiating their relative entropy, and prioritize sequences that exhibit a higher degree of exploration. Together, these mechanisms reduce rollout demand while preserving competitive performance. On the Qwen and Llama models, PREPO achieves effective results on mathematical reasoning benchmarks with up to 3 times fewer rollouts than the baselines. Beyond empirical gains, we provide theoretical and in-depth analyses explaining the underlying rationale of our method to improve the data efficiency of RLVR.

Jia Guo, Shuai Lu, Weihang Zhang et al.

Recent studies highlighted a practical setting of unsupervised anomaly detection (UAD) that builds a unified model for multi-class images. Despite various advancements addressing this challenging task, the detection performance under the multi-class setting still lags far behind state-of-the-art class-separated models. Our research aims to bridge this substantial performance gap. In this paper, we introduce a minimalistic reconstruction-based anomaly detection framework, namely Dinomaly, which leverages pure Transformer architectures without relying on complex designs, additional modules, or specialized tricks. Given this powerful framework consisted of only Attentions and MLPs, we found four simple components that are essential to multi-class anomaly detection: (1) Foundation Transformers that extracts universal and discriminative features, (2) Noisy Bottleneck where pre-existing Dropouts do all the noise injection tricks, (3) Linear Attention that naturally cannot focus, and (4) Loose Reconstruction that does not force layer-to-layer and point-by-point reconstruction. Extensive experiments are conducted across popular anomaly detection benchmarks including MVTec-AD, VisA, and Real-IAD. Our proposed Dinomaly achieves impressive image-level AUROC of 99.6%, 98.7%, and 89.3% on the three datasets respectively, which is not only superior to state-of-the-art multi-class UAD methods, but also achieves the most advanced class-separated UAD records.

Siying Cui, Jia Guo, Xiang An et al.

Leveraging Stable Diffusion for the generation of personalized portraits has emerged as a powerful and noteworthy tool, enabling users to create high-fidelity, custom character avatars based on their specific prompts. However, existing personalization methods face challenges, including test-time fine-tuning, the requirement of multiple input images, low preservation of identity, and limited diversity in generated outcomes. To overcome these challenges, we introduce IDAdapter, a tuning-free approach that enhances the diversity and identity preservation in personalized image generation from a single face image. IDAdapter integrates a personalized concept into the generation process through a combination of textual and visual injections and a face identity loss. During the training phase, we incorporate mixed features from multiple reference images of a specific identity to enrich identity-related content details, guiding the model to generate images with more diverse styles, expressions, and angles compared to previous works. Extensive evaluations demonstrate the effectiveness of our method, achieving both diversity and identity fidelity in generated images.

Jiaqi Shang, Haojin Wu, Yinyi Lai et al.

Deformable image registration plays a fundamental role in medical image analysis by enabling spatial alignment of anatomical structures across subjects. While recent deep learning-based approaches have significantly improved computational efficiency, many existing methods remain limited in capturing long-range anatomical correspondence and maintaining deformation consistency. In this work, we present a cycle inverse-consistent transformer-based framework for deformable brain MRI registration. The model integrates a Swin-UNet architecture with bidirectional consistency constraints, enabling the joint estimation of forward and backward deformation fields. This design allows the framework to capture both local anatomical details and global spatial relationships while improving deformation stability. We conduct a comprehensive evaluation of the proposed framework on a large multi-center dataset consisting of 2851 T1-weighted brain MRI scans aggregated from 13 public datasets. Experimental results demonstrate that the proposed framework achieves strong and balanced performance across multiple quantitative evaluation metrics while maintaining stable and physically plausible deformation fields. Detailed quantitative comparisons with baseline methods, including ANTs, ICNet, and VoxelMorph, are provided in the appendix. Experimental results demonstrate that CICTM achieves consistently strong performance across multiple evaluation criteria while maintaining stable and physically plausible deformation fields. These properties make the proposed framework suitable for large-scale neuroimaging datasets where both accuracy and deformation stability are critical.

Xingyu Ren, Jiankang Deng, Yuhao Cheng et al.

Recent 3D face reconstruction methods have made remarkable advancements, yet there remain huge challenges in monocular high-quality facial reflectance reconstruction. Existing methods rely on a large amount of light-stage captured data to learn facial reflectance models. However, the lack of subject diversity poses challenges in achieving good generalization and widespread applicability. In this paper, we learn the reflectance prior in image space rather than UV space and present a framework named ID2Reflectance. Our framework can directly estimate the reflectance maps of a single image while using limited reflectance data for training. Our key insight is that reflectance data shares facial structures with RGB faces, which enables obtaining expressive facial prior from inexpensive RGB data thus reducing the dependency on reflectance data. We first learn a high-quality prior for facial reflectance. Specifically, we pretrain multi-domain facial feature codebooks and design a codebook fusion method to align the reflectance and RGB domains. Then, we propose an identity-conditioned swapping module that injects facial identity from the target image into the pre-trained autoencoder to modify the identity of the source reflectance image. Finally, we stitch multi-view swapped reflectance images to obtain renderable assets. Extensive experiments demonstrate that our method exhibits excellent generalization capability and achieves state-of-the-art facial reflectance reconstruction results for in-the-wild faces. Our project page is https://xingyuren.github.io/id2reflectance/.

Ling Team, Bin Hu, Cai Chen et al.

We present Ring-lite, a Mixture-of-Experts (MoE)-based large language model optimized via reinforcement learning (RL) to achieve efficient and robust reasoning capabilities. Built upon the publicly available Ling-lite model, a 16.8 billion parameter model with 2.75 billion activated parameters, our approach matches the performance of state-of-the-art (SOTA) small-scale reasoning models on challenging benchmarks (e.g., AIME, LiveCodeBench, GPQA-Diamond) while activating only one-third of the parameters required by comparable models. To accomplish this, we introduce a joint training pipeline integrating distillation with RL, revealing undocumented challenges in MoE RL training. First, we identify optimization instability during RL training, and we propose Constrained Contextual Computation Policy Optimization(C3PO), a novel approach that enhances training stability and improves computational throughput via algorithm-system co-design methodology. Second, we empirically demonstrate that selecting distillation checkpoints based on entropy loss for RL training, rather than validation metrics, yields superior performance-efficiency trade-offs in subsequent RL training. Finally, we develop a two-stage training paradigm to harmonize multi-domain data integration, addressing domain conflicts that arise in training with mixed dataset. We will release the model, dataset, and code.

Yinyi Lai, Anbo Cao, Yuan Gao et al.

Early and accurate diagnosis of brain tumors is crucial for improving patient survival rates. However, the detection and classification of brain tumors are challenging due to their diverse types and complex morphological characteristics. This study investigates the application of pre-trained models for brain tumor classification, with a particular focus on deploying the Mamba model. We fine-tuned several mainstream transfer learning models and applied them to the multi-class classification of brain tumors. By comparing these models to those trained from scratch, we demonstrated the significant advantages of transfer learning, especially in the medical imaging field, where annotated data is often limited. Notably, we introduced the Vision Mamba (Vim), a novel network architecture, and applied it for the first time in brain tumor classification, achieving exceptional classification accuracy. Experimental results indicate that the Vim model achieved 100% classification accuracy on an independent test set, emphasizing its potential for tumor classification tasks. These findings underscore the effectiveness of transfer learning in brain tumor classification and reveal that, compared to existing state-of-the-art models, the Vim model is lightweight, efficient, and highly accurate, offering a new perspective for clinical applications. Furthermore, the framework proposed in this study for brain tumor classification, based on transfer learning and the Vision Mamba model, is broadly applicable to other medical imaging classification problems.

Jordan Jomsky, Zongyu Li, Yiren Zhang et al.

The increasing global aging population necessitates improved methods to assess brain aging and its related neurodegenerative changes. Brain Age Gap Estimation (BrainAGE) offers a neuroimaging biomarker for understanding these changes by predicting brain age from MRI scans. Current approaches primarily use T1-weighted magnetic resonance imaging (T1w MRI) data, capturing only structural brain information. To address this limitation, AI-generated Cerebral Blood Volume (AICBV) data, synthesized from non-contrast MRI scans, offers functional insights by revealing subtle blood-tissue contrasts otherwise undetectable in standard imaging. We integrated AICBV with T1w MRI to predict brain age, combining both structural and functional metrics. We developed a deep learning model using a VGG-based architecture for both modalities and combined their predictions using linear regression. Our model achieved a mean absolute error (MAE) of 3.95 years and an $R^2$ of 0.943 on the test set ($n = 288$), outperforming existing models trained on similar data. We have further created gradient-based class activation maps (Grad-CAM) to visualize the regions of the brain that most influenced the model's predictions, providing interpretable insights into the structural and functional contributors to brain aging.

Jia Guo, Longxu Dou, Guangtao Zeng et al.

In this paper, we introduce SailCompass, a reproducible and robust evaluation benchmark for assessing Large Language Models (LLMs) on Southeast Asian Languages (SEA). SailCompass encompasses three main SEA languages, eight primary tasks including 14 datasets covering three task types (generation, multiple-choice questions, and classification). To improve the robustness of the evaluation approach, we explore different prompt configurations for multiple-choice questions and leverage calibrations to improve the faithfulness of classification tasks. With SailCompass, we derive the following findings: (1) SEA-specialized LLMs still outperform general LLMs, although the gap has narrowed; (2) A balanced language distribution is important for developing better SEA-specialized LLMs; (3) Advanced prompting techniques (e.g., calibration, perplexity-based ranking) are necessary to better utilize LLMs. All datasets and evaluation scripts are public.

Jia Guo, Haonan Han, Shuai Lu et al.

Conventional unsupervised anomaly detection (UAD) methods build separate models for each object category. Recent studies have proposed to train a unified model for multiple classes, namely model-unified UAD. However, such methods still implement the unified model separately on each class during inference with respective anomaly decision thresholds, which hinders their application when the image categories are entirely unavailable. In this work, we present a simple yet powerful method to address multi-class anomaly detection without any class information, namely \textit{absolute-unified} UAD. We target the crux of prior works in this challenging setting: different objects have mismatched anomaly score distributions. We propose Class-Agnostic Distribution Alignment (CADA) to align the mismatched score distribution of each implicit class without knowing class information, which enables unified anomaly detection for all classes and samples. The essence of CADA is to predict each class's score distribution of normal samples given any image, normal or anomalous, of this class. As a general component, CADA can activate the potential of nearly all UAD methods under absolute-unified setting. Our approach is extensively evaluated under the proposed setting on two popular UAD benchmark datasets, MVTec AD and VisA, where we exceed previous state-of-the-art by a large margin.

Anbo Cao, Pin-Yu Le, Zhonghui Qie et al.

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is widely used to evaluate acute ischemic stroke to distinguish salvageable tissue and infarct core. For this purpose, traditional methods employ deconvolution techniques, like singular value decomposition, which are known to be vulnerable to noise, potentially distorting the derived perfusion parameters. However, deep learning technology could leverage it, which can accurately estimate clinical perfusion parameters compared to traditional clinical approaches. Therefore, this study presents a perfusion parameters estimation network that considers spatial and temporal information, the Spatiotemporal Network (ST-Net), for the first time. The proposed network comprises a designed physical loss function to enhance model performance further. The results indicate that the network can accurately estimate perfusion parameters, including cerebral blood volume (CBV), cerebral blood flow (CBF), and time to maximum of the residual function (Tmax). The structural similarity index (SSIM) mean values for CBV, CBF, and Tmax parameters were 0.952, 0.943, and 0.863, respectively. The DICE score for the hypo-perfused region reached 0.859, demonstrating high consistency. The proposed model also maintains time efficiency, closely approaching the performance of commercial gold-standard software.

Aaron Cao, Vishwanatha M. Rao, Kejia Liu et al.

Subcortical segmentation remains challenging despite its important applications in quantitative structural analysis of brain MRI scans. The most accurate method, manual segmentation, is highly labor intensive, so automated tools like FreeSurfer have been adopted to handle this task. However, these traditional pipelines are slow and inefficient for processing large datasets. In this study, we propose TABSurfer, a novel 3D patch-based CNN-Transformer hybrid deep learning model designed for superior subcortical segmentation compared to existing state-of-the-art tools. To evaluate, we first demonstrate TABSurfer's consistent performance across various T1w MRI datasets with significantly shorter processing times compared to FreeSurfer. Then, we validate against manual segmentations, where TABSurfer outperforms FreeSurfer based on the manual ground truth. In each test, we also establish TABSurfer's advantage over a leading deep learning benchmark, FastSurferVINN. Together, these studies highlight TABSurfer's utility as a powerful tool for fully automated subcortical segmentation with high fidelity.

Weijia Feng, Jingyu Yang, Ruojia Zhang et al.

Micro-gestures are subtle and transient movements triggered by unconscious neural and emotional activities, holding great potential for human-computer interaction and clinical monitoring. However, their low amplitude, short duration, and strong inter-subject variability make existing deep models prone to degradation under low-sample, noisy, and cross-subject conditions. This paper presents an active inference-based framework for micro-gesture recognition, featuring Expected Free Energy (EFE)-guided temporal sampling and uncertainty-aware adaptive learning. The model actively selects the most discriminative temporal segments under EFE guidance, enabling dynamic observation and information gain maximization. Meanwhile, sample weighting driven by predictive uncertainty mitigates the effects of label noise and distribution shift. Experiments on the SMG dataset demonstrate the effectiveness of the proposed method, achieving consistent improvements across multiple mainstream backbones. Ablation studies confirm that both the EFE-guided observation and the adaptive learning mechanism are crucial to the performance gains. This work offers an interpretable and scalable paradigm for temporal behavior modeling under low-resource and noisy conditions, with broad applicability to wearable sensing, HCI, and clinical emotion monitoring.

Shuai Lu, Meng Wang, Jia Guo et al.

Large Vision Language Models (LVLMs) show immense potential for automated ophthalmic diagnosis. However, their clinical deployment is severely hindered by lacking domain-specific knowledge. In this work, we identify two structural deficiencies hindering reliable medical reasoning: 1) the Perception Gap, where general-purpose visual encoders fail to resolve fine-grained pathological cues (e.g., microaneurysms); and 2) the Reasoning Gap, where sparse visual evidence is progressively overridden by massive language priors in deeper transformer layers, leading to ungrounded hallucinations. To bridge these gaps, we propose EyExIn, a data-efficient framework designed to anchor retinal VLMs with expert knowledge via a Deep Expert Injection mechanism. Our architecture employs an Expert-Aware Dual-Stream encoding strategy that decouples visual representation into a general stream for anatomical context and a specialized expert stream for pathological semantics. To ensure high-fidelity integration, we design a Semantic-Adaptive Gated Fusion module, which dynamically amplifies subtle lesion signals while filtering irrelevant background noise. Furthermore, we introduce Adaptive Deep Expert Injection to embed persistent "Vision Anchors" by integrating fused visual features as residual biases directly into intermediate LLM layers. This mechanism creates a visual shortcut that forces the reasoning stack to remain strictly grounded in visual evidence. Extensive experiments across four benchmarks demonstrate that our model consistently outperforms massive proprietary systems. EyExIn significantly enhances domain-specific knowledge embedding and achieves state-of-the-art precision in ophthalmic visual question answering, advancing the development of trustworthy ophthalmic AI.

Praveen Chaganlal, Jia Guo, Vivek Vaidyanathan et al.

Real-time OLAP datastores are critical infrastructure for modern enterprises, powering interactive analytics on petabyte-scale datasets with subsecond latency requirements. As these systems become integral to service architectures, maintaining strict SLAs under failures, load spikes, and cluster changes is as important as raw performance. We present a set of resiliency mechanisms developed for Apache Pinot at LinkedIn, applicable to modern OLAP systems broadly. We introduce Query Workload Isolation (QWI), which provides workload-level CPU and memory budgeting across Pinot's broker and server tiers via fine-grained resource accounting and sub-millisecond enforcement, delivering predictable tail latency and fairness with under 1% overhead. We present Impact-Free Rebalancing for SLA-safe data movement during routine operations (e.g., upgrades, scale-out, and recovery), and Maintenance Zone Awareness to place replicas across fault domains and mitigate correlated failures. We also describe Adaptive Server Selection, which routes queries using real-time load and performance signals to avoid slow or failing nodes while preserving balanced utilization. Together, these mechanisms form a holistic resiliency framework deployed in production at LinkedIn, enabling stable query latency and high availability at scale.