Sandra Avila

Zahra Mirikharaji, Kumar Abhishek, Alceu Bissoto et al.

Skin cancer is a major public health problem that could benefit from computer-aided diagnosis to reduce the burden of this common disease. Skin lesion segmentation from images is an important step toward achieving this goal. However, the presence of natural and artificial artifacts (e.g., hair and air bubbles), intrinsic factors (e.g., lesion shape and contrast), and variations in image acquisition conditions make skin lesion segmentation a challenging task. Recently, various researchers have explored the applicability of deep learning models to skin lesion segmentation. In this survey, we cross-examine 177 research papers that deal with deep learning-based segmentation of skin lesions. We analyze these works along several dimensions, including input data (datasets, preprocessing, and synthetic data generation), model design (architecture, modules, and losses), and evaluation aspects (data annotation requirements and segmentation performance). We discuss these dimensions both from the viewpoint of select seminal works, and from a systematic viewpoint, examining how those choices have influenced current trends, and how their limitations should be addressed. To facilitate comparisons, we summarize all examined works in a comprehensive table as well as an interactive table available online at https://github.com/sfu-mial/skin-lesion-segmentation-survey.

Gabriel Oliveira dos Santos, Diego A. B. Moreira, Alef Iury Ferreira et al.

This work introduces CAPIVARA, a cost-efficient framework designed to enhance the performance of multilingual CLIP models in low-resource languages. While CLIP has excelled in zero-shot vision-language tasks, the resource-intensive nature of model training remains challenging. Many datasets lack linguistic diversity, featuring solely English descriptions for images. CAPIVARA addresses this by augmenting text data using image captioning and machine translation to generate multiple synthetic captions in low-resource languages. We optimize the training pipeline with LiT, LoRA, and gradient checkpointing to alleviate the computational cost. Through extensive experiments, CAPIVARA emerges as state of the art in zero-shot tasks involving images and Portuguese texts. We show the potential for significant improvements in other low-resource languages, achieved by fine-tuning the pre-trained multilingual CLIP using CAPIVARA on a single GPU for 2 hours. Our model and code is available at https://github.com/hiaac-nlp/CAPIVARA.

Camila Laranjeira, João Macedo, Sandra Avila et al.

The online sharing and viewing of Child Sexual Abuse Material (CSAM) are growing fast, such that human experts can no longer handle the manual inspection. However, the automatic classification of CSAM is a challenging field of research, largely due to the inaccessibility of target data that is - and should forever be - private and in sole possession of law enforcement agencies. To aid researchers in drawing insights from unseen data and safely providing further understanding of CSAM images, we propose an analysis template that goes beyond the statistics of the dataset and respective labels. It focuses on the extraction of automatic signals, provided both by pre-trained machine learning models, e.g., object categories and pornography detection, as well as image metrics such as luminance and sharpness. Only aggregated statistics of sparse signals are provided to guarantee the anonymity of children and adolescents victimized. The pipeline allows filtering the data by applying thresholds to each specified signal and provides the distribution of such signals within the subset, correlations between signals, as well as a bias evaluation. We demonstrated our proposal on the Region-based annotated Child Pornography Dataset (RCPD), one of the few CSAM benchmarks in the literature, composed of over 2000 samples among regular and CSAM images, produced in partnership with Brazil's Federal Police. Although noisy and limited in several senses, we argue that automatic signals can highlight important aspects of the overall distribution of data, which is valuable for databases that can not be disclosed. Our goal is to safely publicize the characteristics of CSAM datasets, encouraging researchers to join the field and perhaps other institutions to provide similar reports on their benchmarks.

Diego A. B. Moreira, Alef Iury Ferreira, Jhessica Silva et al.

Despite significant advancements and pervasive use of vision-language models, a paucity of studies has addressed their ethical implications. These models typically require extensive training data, often from hastily reviewed text and image datasets, leading to highly imbalanced datasets and ethical concerns. Additionally, models initially trained in English are frequently fine-tuned for other languages, such as the CLIP model, which can be expanded with more data to enhance capabilities but can add new biases. The CAPIVARA, a CLIP-based model adapted to Portuguese, has shown strong performance in zero-shot tasks. In this paper, we evaluate four different types of discriminatory practices within visual-language models and introduce FairPIVARA, a method to reduce them by removing the most affected dimensions of feature embeddings. The application of FairPIVARA has led to a significant reduction of up to 98% in observed biases while promoting a more balanced word distribution within the model. Our model and code are available at: https://github.com/hiaac-nlp/FairPIVARA.

Alceu Bissoto, Catarina Barata, Eduardo Valle et al.

Deep Learning failure cases are abundant, particularly in the medical area. Recent studies in out-of-distribution generalization have advanced considerably on well-controlled synthetic datasets, but they do not represent medical imaging contexts. We propose a pipeline that relies on artifacts annotation to enable generalization evaluation and debiasing for the challenging skin lesion analysis context. First, we partition the data into levels of increasingly higher biased training and test sets for better generalization assessment. Then, we create environments based on skin lesion artifacts to enable domain generalization methods. Finally, after robust training, we perform a test-time debiasing procedure, reducing spurious features in inference images. Our experiments show our pipeline improves performance metrics in biased cases, and avoids artifacts when using explanation methods. Still, when evaluating such models in out-of-distribution data, they did not prefer clinically-meaningful features. Instead, performance only improved in test sets that present similar artifacts from training, suggesting models learned to ignore the known set of artifacts. Our results raise a concern that debiasing models towards a single aspect may not be enough for fair skin lesion analysis.

Levy Chaves, Alceu Bissoto, Eduardo Valle et al.

Transfer learning boosts the performance of medical image analysis by enabling deep learning (DL) on small datasets through the knowledge acquired from large ones. As the number of DL architectures explodes, exhaustively attempting all candidates becomes unfeasible, motivating cheaper alternatives for choosing them. Transferability scoring methods emerge as an enticing solution, allowing to efficiently calculate a score that correlates with the architecture accuracy on any target dataset. However, since transferability scores have not been evaluated on medical datasets, their use in this context remains uncertain, preventing them from benefiting practitioners. We fill that gap in this work, thoroughly evaluating seven transferability scores in three medical applications, including out-of-distribution scenarios. Despite promising results in general-purpose datasets, our results show that no transferability score can reliably and consistently estimate target performance in medical contexts, inviting further work in that direction.

Alceu Bissoto, Catarina Barata, Eduardo Valle et al.

Skin lesion analysis models are biased by artifacts placed during image acquisition, which influence model predictions despite carrying no clinical information. Solutions that address this problem by regularizing models to prevent learning those spurious features achieve only partial success, and existing test-time debiasing techniques are inappropriate for skin lesion analysis due to either making unrealistic assumptions on the distribution of test data or requiring laborious annotation from medical practitioners. We propose TTS (Test-Time Selection), a human-in-the-loop method that leverages positive (e.g., lesion area) and negative (e.g., artifacts) keypoints in test samples. TTS effectively steers models away from exploiting spurious artifact-related correlations without retraining, and with less annotation requirements. Our solution is robust to a varying availability of annotations, and different levels of bias. We showcase on the ISIC2019 dataset (for which we release a subset of annotated images) how our model could be deployed in the real-world for mitigating bias.

Luana Barros, Levy Chaves, Sandra Avila

Melanoma is the most severe type of skin cancer due to its ability to cause metastasis. It is more common in black people, often affecting acral regions: palms, soles, and nails. Deep neural networks have shown tremendous potential for improving clinical care and skin cancer diagnosis. Nevertheless, prevailing studies predominantly rely on datasets of white skin tones, neglecting to report diagnostic outcomes for diverse patient skin tones. In this work, we evaluate supervised and self-supervised models in skin lesion images extracted from acral regions commonly observed in black individuals. Also, we carefully curate a dataset containing skin lesions in acral regions and assess the datasets concerning the Fitzpatrick scale to verify performance on black skin. Our results expose the poor generalizability of these models, revealing their favorable performance for lesions on white skin. Neglecting to create diverse datasets, which necessitates the development of specialized models, is unacceptable. Deep neural networks have great potential to improve diagnosis, particularly for populations with limited access to dermatology. However, including black skin lesions is necessary to ensure these populations can access the benefits of inclusive technology.

Gabriel Oliveira dos Santos, Esther Luna Colombini, Sandra Avila

Automatically describing images using natural sentences is an important task to support visually impaired people's inclusion onto the Internet. It is still a big challenge that requires understanding the relation of the objects present in the image and their attributes and actions they are involved in. Then, visual interpretation methods are needed, but linguistic models are also necessary to verbally describe the semantic relations. This problem is known as Image Captioning. Although many datasets were proposed in the literature, the majority contains only English captions, whereas datasets with captions described in other languages are scarce. Recently, a movement called PraCegoVer arose on the Internet, stimulating users from social media to publish images, tag #PraCegoVer and add a short description of their content. Thus, inspired by this movement, we have proposed the #PraCegoVer, a multi-modal dataset with Portuguese captions based on posts from Instagram. It is the first large dataset for image captioning in Portuguese with freely annotated images. Further, the captions in our dataset bring additional challenges to the problem: first, in contrast to popular datasets such as MS COCO Captions, #PraCegoVer has only one reference to each image; also, both mean and variance of our reference sentence length are significantly greater than those in the MS COCO Captions. These two characteristics contribute to making our dataset interesting due to the linguistic aspect and the challenges that it introduces to the image captioning problem. We publicly-share the dataset at https://github.com/gabrielsantosrv/PraCegoVer.

Yu Xie, Sofia Avila

Liking it or not, ready or not, we are likely to enter a new phase of human history in which Artificial Intelligence (AI) will dominate economic production and social life -- the AI Revolution. Before the actual arrival of the AI Revolution, it is time for us to speculate on how AI will impact the social world. In this article, we focus on the social impact of generative LLM-based AI (GELLMAI), discussing societal factors that contribute to its technological development and its potential roles in enhancing both between-country and within-country social inequality. There are good indications that the US and China will lead the field and will be the main competitors for domination of AI in the world. We conjecture the AI Revolution will likely give rise to a post-knowledge society in which knowledge per se will become less important than in today's world. Instead, individual relationships and social identity will become more important. So will soft skills.

Rosa Y. G. Paccotacya-Yanque, Alceu Bissoto, Sandra Avila

Deep Learning has shown outstanding results in computer vision tasks; healthcare is no exception. However, there is no straightforward way to expose the decision-making process of DL models. Good accuracy is not enough for skin cancer predictions. Understanding the model's behavior is crucial for clinical application and reliable outcomes. In this work, we identify desiderata for explanations in skin-lesion models. We analyzed seven methods, four based on pixel-attribution (Grad-CAM, Score-CAM, LIME, SHAP) and three on high-level concepts (ACE, ICE, CME), for a deep neural network trained on the International Skin Imaging Collaboration Archive. Our findings indicate that while these techniques reveal biases, there is room for improving the comprehensiveness of explanations to achieve transparency in skin-lesion models.

Pedro H. V. Valois, João Macedo, Leo S. F. Ribeiro et al.

Crime in the 21st century is split into a virtual and real world. However, the former has become a global menace to people's well-being and security in the latter. The challenges it presents must be faced with unified global cooperation, and we must rely more than ever on automated yet trustworthy tools to combat the ever-growing nature of online offenses. Over 10 million child sexual abuse reports are submitted to the US National Center for Missing \& Exploited Children every year, and over 80% originate from online sources. Therefore, investigation centers cannot manually process and correctly investigate all imagery. In light of that, reliable automated tools that can securely and efficiently deal with this data are paramount. In this sense, the scene classification task looks for contextual cues in the environment, being able to group and classify child sexual abuse data without requiring to be trained on sensitive material. The scarcity and limitations of working with child sexual abuse images lead to self-supervised learning, a machine-learning methodology that leverages unlabeled data to produce powerful representations that can be more easily transferred to downstream tasks. This work shows that self-supervised deep learning models pre-trained on scene-centric data can reach 71.6% balanced accuracy on our indoor scene classification task and, on average, 2.2 percentage points better performance than a fully supervised version. We cooperate with Brazilian Federal Police experts to evaluate our indoor classification model on actual child abuse material. The results demonstrate a notable discrepancy between the features observed in widely used scene datasets and those depicted on sensitive materials.

Thamiris Coelho, Leo S. F. Ribeiro, João Macedo et al.

The distribution of child sexual abuse imagery (CSAI) is an ever-growing concern of our modern world; children who suffered from this heinous crime are revictimized, and the growing amount of illegal imagery distributed overwhelms law enforcement agents (LEAs) with the manual labor of categorization. To ease this burden researchers have explored methods for automating data triage and detection of CSAI, but the sensitive nature of the data imposes restricted access and minimal interaction between real data and learning algorithms, avoiding leaks at all costs. In observing how these restrictions have shaped the literature we formalize a definition of "Proxy Tasks", i.e., the substitute tasks used for training models for CSAI without making use of CSA data. Under this new terminology we review current literature and present a protocol for making conscious use of Proxy Tasks together with consistent input from LEAs to design better automation in this field. Finally, we apply this protocol to study -- for the first time -- the task of Few-shot Indoor Scene Classification on CSAI, showing a final model that achieves promising results on a real-world CSAI dataset whilst having no weights actually trained on sensitive data.

Gustavo Bonil, João Gondim, Marina dos Santos et al.

This study investigates how large language models, in particular LLaMA 3.2-3B, construct narratives about Black and white women in short stories generated in Portuguese. From 2100 texts, we applied computational methods to group semantically similar stories, allowing a selection for qualitative analysis. Three main discursive representations emerge: social overcoming, ancestral mythification and subjective self-realization. The analysis uncovers how grammatically coherent, seemingly neutral texts materialize a crystallized, colonially structured framing of the female body, reinforcing historical inequalities. The study proposes an integrated approach, that combines machine learning techniques with qualitative, manual discourse analysis.

Carlos Caetano, Gabriel O. dos Santos, Caio Petrucci et al.

Including children's images in datasets has raised ethical concerns, particularly regarding privacy, consent, data protection, and accountability. These datasets, often built by scraping publicly available images from the Internet, can expose children to risks such as exploitation, profiling, and tracking. Despite the growing recognition of these issues, approaches for addressing them remain limited. We explore the ethical implications of using children's images in AI datasets and propose a pipeline to detect and remove such images. As a use case, we built the pipeline on a Vision-Language Model under the Visual Question Answering task and tested it on the #PraCegoVer dataset. We also evaluate the pipeline on a subset of 100,000 images from the Open Images V7 dataset to assess its effectiveness in detecting and removing images of children. The pipeline serves as a baseline for future research, providing a starting point for more comprehensive tools and methodologies. While we leverage existing models trained on potentially problematic data, our goal is to expose and address this issue. We do not advocate for training or deploying such models, but instead call for urgent community reflection and action to protect children's rights. Ultimately, we aim to encourage the research community to exercise - more than an additional - care in creating new datasets and to inspire the development of tools to protect the fundamental rights of vulnerable groups, particularly children.

Raysa Benatti, Fabiana Severi, Sandra Avila et al.

Data derived from the realm of the social sciences is often produced in digital text form, which motivates its use as a source for natural language processing methods. Researchers and practitioners have developed and relied on artificial intelligence techniques to collect, process, and analyze documents in the legal field, especially for tasks such as text summarization and classification. While increasing procedural efficiency is often the primary motivation behind natural language processing in the field, several works have proposed solutions for human rights-related issues, such as assessment of public policy and institutional social settings. One such issue is the presence of gender biases in court decisions, which has been largely studied in social sciences fields; biased institutional responses to gender-based violence are a violation of international human rights dispositions since they prevent gender minorities from accessing rights and hamper their dignity. Natural language processing-based approaches can help detect these biases on a larger scale. Still, the development and use of such tools require researchers and practitioners to be mindful of legal and ethical aspects concerning data sharing and use, reproducibility, domain expertise, and value-charged choices. In this work, we (a) present an experimental framework developed to automatically detect gender biases in court decisions issued in Brazilian Portuguese and (b) describe and elaborate on features we identify to be critical in such a technology, given its proposed use as a support tool for research and assessment of court~activity.

Alceu Bissoto, Catarina Barata, Eduardo Valle et al.

Distribution shifts are common in real-world datasets and can affect the performance and reliability of deep learning models. In this paper, we study two types of distribution shifts: diversity shifts, which occur when test samples exhibit patterns unseen during training, and correlation shifts, which occur when test data present a different correlation between seen invariant and spurious features. We propose an integrated protocol to analyze both types of shifts using datasets where they co-exist in a controllable manner. Finally, we apply our approach to a real-world classification problem of skin cancer analysis, using out-of-distribution datasets and specialized bias annotations. Our protocol reveals three findings: 1) Models learn and propagate correlation shifts even with low-bias training; this poses a risk of accumulating and combining unaccountable weak biases; 2) Models learn robust features in high- and low-bias scenarios but use spurious ones if test samples have them; this suggests that spurious correlations do not impair the learning of robust features; 3) Diversity shift can reduce the reliance on spurious correlations; this is counter intuitive since we expect biased models to depend more on biases when invariant features are missing. Our work has implications for distribution shift research and practice, providing new insights into how models learn and rely on spurious correlations under different types of shifts.

Edson Bollis, Helena Maia, Helio Pedrini et al.

Citrus juices and fruits are commodities with great economic potential in the international market, but productivity losses caused by mites and other pests are still far from being a good mark. Despite the integrated pest mechanical aspect, only a few works on automatic classification have handled images with orange mite characteristics, which means tiny and noisy regions of interest. On the computational side, attention-based models have gained prominence in deep learning research, and, along with weakly supervised learning algorithms, they have improved tasks performed with some label restrictions. In agronomic research of pests and diseases, these techniques can improve classification performance while pointing out the location of mites and insects without specific labels, reducing deep learning development costs related to generating bounding boxes. In this context, this work proposes an attention-based activation map approach developed to improve the classification of tiny regions called Two-Weighted Activation Mapping, which also produces locations using feature map scores learned from class labels. We apply our method in a two-stage network process called Attention-based Multiple Instance Learning Guided by Saliency Maps. We analyze the proposed approach in two challenging datasets, the Citrus Pest Benchmark, which was captured directly in the field using magnifying glasses, and the Insect Pest, a large pest image benchmark. In addition, we evaluate and compare our models with weakly supervised methods, such as Attention-based Deep MIL and WILDCAT. The results show that our classifier is superior to literature methods that use tiny regions in their classification tasks, surpassing them in all scenarios by at least 16 percentage points. Moreover, our approach infers bounding box locations for salient insects, even training without any location labels.

Gabriel Oliveira dos Santos, Esther Luna Colombini, Sandra Avila

This paper shows that CIDEr-D, a traditional evaluation metric for image description, does not work properly on datasets where the number of words in the sentence is significantly greater than those in the MS COCO Captions dataset. We also show that CIDEr-D has performance hampered by the lack of multiple reference sentences and high variance of sentence length. To bypass this problem, we introduce CIDEr-R, which improves CIDEr-D, making it more flexible in dealing with datasets with high sentence length variance. We demonstrate that CIDEr-R is more accurate and closer to human judgment than CIDEr-D; CIDEr-R is more robust regarding the number of available references. Our results reveal that using Self-Critical Sequence Training to optimize CIDEr-R generates descriptive captions. In contrast, when CIDEr-D is optimized, the generated captions' length tends to be similar to the reference length. However, the models also repeat several times the same word to increase the sentence length.

Levy Chaves, Alceu Bissoto, Eduardo Valle et al.

Self-supervised pre-training appears as an advantageous alternative to supervised pre-trained for transfer learning. By synthesizing annotations on pretext tasks, self-supervision allows to pre-train models on large amounts of pseudo-labels before fine-tuning them on the target task. In this work, we assess self-supervision for the diagnosis of skin lesions, comparing three self-supervised pipelines to a challenging supervised baseline, on five test datasets comprising in- and out-of-distribution samples. Our results show that self-supervision is competitive both in improving accuracies and in reducing the variability of outcomes. Self-supervision proves particularly useful for low training data scenarios ($<1\,500$ and $<150$ samples), where its ability to stabilize the outcomes is essential to provide sound results.

Alceu Bissoto, Eduardo Valle, Sandra Avila

Despite the growing availability of high-quality public datasets, the lack of training samples is still one of the main challenges of deep-learning for skin lesion analysis. Generative Adversarial Networks (GANs) appear as an enticing alternative to alleviate the issue, by synthesizing samples indistinguishable from real images, with a plethora of works employing them for medical applications. Nevertheless, carefully designed experiments for skin-lesion diagnosis with GAN-based data augmentation show favorable results only on out-of-distribution test sets. For GAN-based data anonymization $-$ where the synthetic images replace the real ones $-$ favorable results also only appear for out-of-distribution test sets. Because of the costs and risks associated with GAN usage, those results suggest caution in their adoption for medical applications.

Vinicius Ribeiro, Sandra Avila, Eduardo Valle

Segmenting skin lesions images is relevant both for itself and for assisting in lesion classification, but suffers from the challenge in obtaining annotated data. In this work, we show that segmentation may improve with less data, by selecting the training samples with best inter-annotator agreement, and conditioning the ground-truth masks to remove excessive detail. We perform an exhaustive experimental design considering several sources of variation, including three different test sets, two different deep-learning architectures, and several replications, for a total of 540 experimental runs. We found that sample selection and detail removal may have impacts corresponding, respectively, to 12% and 16% of the one obtained by picking a better deep-learning model.

Alceu Bissoto, Eduardo Valle, Sandra Avila

Data-driven models are now deployed in a plethora of real-world applications - including automated diagnosis - but models learned from data risk learning biases from that same data. When models learn spurious correlations not found in real-world situations, their deployment for critical tasks, such as medical decisions, can be catastrophic. In this work we address this issue for skin-lesion classification models, with two objectives: finding out what are the spurious correlations exploited by biased networks, and debiasing the models by removing such spurious correlations from them. We perform a systematic integrated analysis of 7 visual artifacts (which are possible sources of biases exploitable by networks), employ a state-of-the-art technique to prevent the models from learning spurious correlations, and propose datasets to test models for the presence of bias. We find out that, despite interesting results that point to promising future research, current debiasing methods are not ready to solve the bias issue for skin-lesion models.

Edson Bollis, Helio Pedrini, Sandra Avila

Pests and diseases are relevant factors for production losses in agriculture and, therefore, promote a huge investment in the prevention and detection of its causative agents. In many countries, Integrated Pest Management is the most widely used process to prevent and mitigate the damages caused by pests and diseases in citrus crops. However, its results are credited by humans who visually inspect the orchards in order to identify the disease symptoms, insects and mite pests. In this context, we design a weakly supervised learning process guided by saliency maps to automatically select regions of interest in the images, significantly reducing the annotation task. In addition, we create a large citrus pest benchmark composed of positive samples (six classes of mite species) and negative samples. Experiments conducted on two large datasets demonstrate that our results are very promising for the problem of pest and disease classification in the agriculture field.

Alceu Bissoto, Eduardo Valle, Sandra Avila

Generative Adversarial Networks fostered a newfound interest in generative models, resulting in a swelling wave of new works that new-coming researchers may find formidable to surf. In this paper, we intend to help those researchers, by splitting that incoming wave into six "fronts": Architectural Contributions, Conditional Techniques, Normalization and Constraint Contributions, Loss Functions, Image-to-image Translations, and Validation Metrics. The division in fronts organizes literature into approachable blocks, ultimately communicating to the reader how the area is evolving. Previous surveys in the area, which this works also tabulates, focus on a few of those fronts, leaving a gap that we propose to fill with a more integrated, comprehensive overview. Here, instead of an exhaustive survey, we opt for a straightforward review: our target is to be an entry point to this vast literature, and also to be able to update experienced researchers to the newest techniques.

Thiago T. Santos, Leonardo L. de Souza, Andreza A. dos Santos et al.

Agricultural applications such as yield prediction, precision agriculture and automated harvesting need systems able to infer the crop state from low-cost sensing devices. Proximal sensing using affordable cameras combined with computer vision has seen a promising alternative, strengthened after the advent of convolutional neural networks (CNNs) as an alternative for challenging pattern recognition problems in natural images. Considering fruit growing monitoring and automation, a fundamental problem is the detection, segmentation and counting of individual fruits in orchards. Here we show that for wine grapes, a crop presenting large variability in shape, color, size and compactness, grape clusters can be successfully detected, segmented and tracked using state-of-the-art CNNs. In a test set containing 408 grape clusters from images taken on a trellis-system based vineyard, we have reached an F 1 -score up to 0.91 for instance segmentation, a fine separation of each cluster from other structures in the image that allows a more accurate assessment of fruit size and shape. We have also shown as clusters can be identified and tracked along video sequences recording orchard rows. We also present a public dataset containing grape clusters properly annotated in 300 images and a novel annotation methodology for segmentation of complex objects in natural images. The presented pipeline for annotation, training, evaluation and tracking of agricultural patterns in images can be replicated for different crops and production systems. It can be employed in the development of sensing components for several agricultural and environmental applications.

Vinicius Ribeiro, Sandra Avila, Eduardo Valle

In this work, we explore the issue of the inter-annotator agreement for training and evaluating automated segmentation of skin lesions. We explore what different degrees of agreement represent, and how they affect different use cases for segmentation. We also evaluate how conditioning the ground truths using different (but very simple) algorithms may help to enhance agreement and may be appropriate for some use cases. The segmentation of skin lesions is a cornerstone task for automated skin lesion analysis, useful both as an end-result to locate/detect the lesions and as an ancillary task for lesion classification. Lesion segmentation, however, is a very challenging task, due not only to the challenge of image segmentation itself but also to the difficulty in obtaining properly annotated data. Detecting accurately the borders of lesions is challenging even for trained humans, since, for many lesions, those borders are fuzzy and ill-defined. Using lesions and annotations from the ISIC Archive, we estimate inter-annotator agreement for skin-lesion segmentation and propose several simple procedures that may help to improve inter-annotator agreement if used to condition the ground truths.

Fábio Perez, Sandra Avila, Eduardo Valle

Convolutional neural networks (CNNs) deliver exceptional results for computer vision, including medical image analysis. With the growing number of available architectures, picking one over another is far from obvious. Existing art suggests that, when performing transfer learning, the performance of CNN architectures on ImageNet correlates strongly with their performance on target tasks. We evaluate that claim for melanoma classification, over 9 CNNs architectures, in 5 sets of splits created on the ISIC Challenge 2017 dataset, and 3 repeated measures, resulting in 135 models. The correlations we found were, to begin with, much smaller than those reported by existing art, and disappeared altogether when we considered only the top-performing networks: uncontrolled nuisances (i.e., splits and randomness) overcome any of the analyzed factors. Whenever possible, the best approach for melanoma classification is still to create ensembles of multiple models. We compared two choices for selecting which models to ensemble: picking them at random (among a pool of high-quality ones) vs. using the validation set to determine which ones to pick first. For small ensembles, we found a slight advantage on the second approach but found that random choice was also competitive. Although our aim in this paper was not to maximize performance, we easily reached AUCs comparable to the first place on the ISIC Challenge 2017.

Akari Ishikawa, Edson Bollis, Sandra Avila

Watching cartoons can be useful for children's intellectual, social and emotional development. However, the most popular video sharing platform today provides many videos with Elsagate content. Elsagate is a phenomenon that depicts childhood characters in disturbing circumstances (e.g., gore, toilet humor, drinking urine, stealing). Even with this threat easily available for children, there is no work in the literature addressing the problem. As the first to explore disturbing content in cartoons, we proceed from the most recent pornography detection literature applying deep convolutional neural networks combined with static and motion information of the video. Our solution is compatible with mobile platforms and achieved 92.6% of accuracy. Our goal is not only to introduce the first solution but also to bring up the discussion around Elsagate.

Alceu Bissoto, Michel Fornaciali, Eduardo Valle et al.

Melanoma is the deadliest form of skin cancer. Automated skin lesion analysis plays an important role for early detection. Nowadays, the ISIC Archive and the Atlas of Dermoscopy dataset are the most employed skin lesion sources to benchmark deep-learning based tools. However, all datasets contain biases, often unintentional, due to how they were acquired and annotated. Those biases distort the performance of machine-learning models, creating spurious correlations that the models can unfairly exploit, or, contrarily destroying cogent correlations that the models could learn. In this paper, we propose a set of experiments that reveal both types of biases, positive and negative, in existing skin lesion datasets. Our results show that models can correctly classify skin lesion images without clinically-meaningful information: disturbingly, the machine-learning model learned over images where no information about the lesion remains, presents an accuracy above the AI benchmark curated with dermatologists' performances. That strongly suggests spurious correlations guiding the models. We fed models with additional clinically meaningful information, which failed to improve the results even slightly, suggesting the destruction of cogent correlations. Our main findings raise awareness of the limitations of models trained and evaluated in small datasets such as the ones we evaluated, and may suggest future guidelines for models intended for real-world deployment.

Alceu Bissoto, Fábio Perez, Eduardo Valle et al.

Skin cancer is by far the most common type of cancer. Early detection is the key to increase the chances for successful treatment significantly. Currently, Deep Neural Networks are the state-of-the-art results on automated skin cancer classification. To push the results further, we need to address the lack of annotated data, which is expensive and require much effort from specialists. To bypass this problem, we propose using Generative Adversarial Networks for generating realistic synthetic skin lesion images. To the best of our knowledge, our results are the first to show visually-appealing synthetic images that comprise clinically-meaningful information.

Fábio Perez, Cristina Vasconcelos, Sandra Avila et al.

Deep learning models show remarkable results in automated skin lesion analysis. However, these models demand considerable amounts of data, while the availability of annotated skin lesion images is often limited. Data augmentation can expand the training dataset by transforming input images. In this work, we investigate the impact of 13 data augmentation scenarios for melanoma classification trained on three CNNs (Inception-v4, ResNet, and DenseNet). Scenarios include traditional color and geometric transforms, and more unusual augmentations such as elastic transforms, random erasing and a novel augmentation that mixes different lesions. We also explore the use of data augmentation at test-time and the impact of data augmentation on various dataset sizes. Our results confirm the importance of data augmentation in both training and testing and show that it can lead to more performance gains than obtaining new images. The best scenario results in an AUC of 0.882 for melanoma classification without using external data, outperforming the top-ranked submission (0.874) for the ISIC Challenge 2017, which was trained with additional data.

Alceu Bissoto, Fábio Perez, Vinícius Ribeiro et al.

This extended abstract describes the participation of RECOD Titans in parts 1 to 3 of the ISIC Challenge 2018 "Skin Lesion Analysis Towards Melanoma Detection" (MICCAI 2018). Although our team has a long experience with melanoma classification and moderate experience with lesion segmentation, the ISIC Challenge 2018 was the very first time we worked on lesion attribute detection. For each task we submitted 3 different ensemble approaches, varying combinations of models and datasets. Our best results on the official testing set, regarding the official metric of each task, were: 0.728 (segmentation), 0.344 (attribute detection) and 0.803 (classification). Those submissions reached, respectively, the 56th, 14th and 9th places.

Eduardo Valle, Michel Fornaciali, Afonso Menegola et al.

Deep learning fostered a leap ahead in automated skin lesion analysis in the last two years. Those models are expensive to train and difficult to parameterize. Objective: We investigate methodological issues for designing and evaluating deep learning models for skin lesion analysis. We explore 10 choices faced by researchers: use of transfer learning, model architecture, train dataset, image resolution, type of data augmentation, input normalization, use of segmentation, duration of training, additional use of SVMs, and test data augmentation. Methods: We perform two full factorial experiments, for five different test datasets, resulting in 2560 exhaustive trials in our main experiment, and 1280 trials in our assessment of transfer learning. We analyze both with multi-way ANOVA. We use the exhaustive trials to simulate sequential decisions and ensembles, with and without the use of privileged information from the test set. Results -- main experiment: Amount of train data has disproportionate influence, explaining almost half the variation in performance. Of the other factors, test data augmentation and input resolution are the most influential. Deeper models, when combined, with extra data, also help. -- transfer experiment: Transfer learning is critical, its absence brings huge performance penalties. -- simulations: Ensembles of models are the best option to provide reliable results with limited resources, without using privileged information and sacrificing methodological rigor. Conclusions and Significance: Advancing research on automated skin lesion analysis requires curating larger public datasets. Indirect use of privileged information from the test set to design the models is a subtle, but frequent methodological mistake that leads to overoptimistic results. Ensembles of models are a cost-effective alternative to the expensive full-factorial and to the unstable sequential designs.

Afonso Menegola, Julia Tavares, Michel Fornaciali et al.

This extended abstract describes the participation of RECOD Titans in parts 1 and 3 of the ISIC Challenge 2017 "Skin Lesion Analysis Towards Melanoma Detection" (ISBI 2017). Although our team has a long experience with melanoma classification, the ISIC Challenge 2017 was the very first time we worked on skin-lesion segmentation. For part 1 (segmentation), our final submission used four of our models: two trained with all 2000 samples, without a validation split, for 250 and for 500 epochs respectively; and other two trained and validated with two different 1600/400 splits, for 220 epochs. Those four models, individually, achieved between 0.780 and 0.783 official validation scores. Our final submission averaged the output of those four models achieved a score of 0.793. For part 3 (classification), the submitted test run as well as our last official validation run were the result from a meta-model that assembled seven base deep-learning models: three based on Inception-V4 trained on our largest dataset; three based on Inception trained on our smallest dataset; and one based on ResNet-101 trained on our smaller dataset. The results of those component models were stacked in a meta-learning layer based on an SVM trained on the validation set of our largest dataset.

Afonso Menegola, Michel Fornaciali, Ramon Pires et al.

Deep learning is the current bet for image classification. Its greed for huge amounts of annotated data limits its usage in medical imaging context. In this scenario transfer learning appears as a prominent solution. In this report we aim to clarify how transfer learning schemes may influence classification results. We are particularly focused in the automated melanoma screening problem, a case of medical imaging in which transfer learning is still not widely used. We explored transfer with and without fine-tuning, sequential transfers and usage of pre-trained models in general and specific datasets. Although some issues remain open, our findings may drive future researches.

Carlos Caetano, Sandra Avila, William Robson Schwartz et al.

With the growing amount of inappropriate content on the Internet, such as pornography, arises the need to detect and filter such material. The reason for this is given by the fact that such content is often prohibited in certain environments (e.g., schools and workplaces) or for certain publics (e.g., children). In recent years, many works have been mainly focused on detecting pornographic images and videos based on visual content, particularly on the detection of skin color. Although these approaches provide good results, they generally have the disadvantage of a high false positive rate since not all images with large areas of skin exposure are necessarily pornographic images, such as people wearing swimsuits or images related to sports. Local feature based approaches with Bag-of-Words models (BoW) have been successfully applied to visual recognition tasks in the context of pornography detection. Even though existing methods provide promising results, they use local feature descriptors that require a high computational processing time yielding high-dimensional vectors. In this work, we propose an approach for pornography detection based on local binary feature extraction and BossaNova image representation, a BoW model extension that preserves more richly the visual information. Moreover, we propose two approaches for video description based on the combination of mid-level representations namely BossaNova Video Descriptor (BNVD) and BoW Video Descriptor (BoW-VD). The proposed techniques are promising, achieving an accuracy of 92.40%, thus reducing the classification error by 16% over the current state-of-the-art local features approach on the Pornography dataset.

Michel Fornaciali, Micael Carvalho, Flávia Vasques Bittencourt et al.

In this paper we survey, analyze and criticize current art on automated melanoma screening, reimplementing a baseline technique, and proposing two novel ones. Melanoma, although highly curable when detected early, ends as one of the most dangerous types of cancer, due to delayed diagnosis and treatment. Its incidence is soaring, much faster than the number of trained professionals able to diagnose it. Automated screening appears as an alternative to make the most of those professionals, focusing their time on the patients at risk while safely discharging the other patients. However, the potential of automated melanoma diagnosis is currently unfulfilled, due to the emphasis of current literature on outdated computer vision models. Even more problematic is the irreproducibility of current art. We show how streamlined pipelines based upon current Computer Vision outperform conventional models - a model based on an advanced bags of words reaches an AUC of 84.6%, and a model based on deep neural networks reaches 89.3%, while the baseline (a classical bag of words) stays at 81.2%. We also initiate a dialog to improve reproducibility in our community

Otávio A. B. Penatti, Sandra Avila, Eduardo Valle et al.

Visual dictionaries are a critical component for image classification/retrieval systems based on the bag-of-visual-words (BoVW) model. Dictionaries are usually learned without supervision from a training set of images sampled from the collection of interest. However, for large, general-purpose, dynamic image collections (e.g., the Web), obtaining a representative sample in terms of semantic concepts is not straightforward. In this paper, we evaluate the impact of semantics in the dictionary quality, aiming at verifying the importance of semantic diversity in relation visual diversity for visual dictionaries. In the experiments, we vary the amount of classes used for creating the dictionary and then compute different BoVW descriptors, using multiple codebook sizes and different coding and pooling methods (standard BoVW and Fisher Vectors). Results for image classification show that as visual dictionaries are based on low-level visual appearances, visual diversity is more important than semantic diversity. Our conclusions open the opportunity to alleviate the burden in generating visual dictionaries as we need only a visually diverse set of images instead of the whole collection to create a good dictionary.