Jie Xu

Yuanyang Zhang, Yijie Lin, Weiqing Yan et al.

Incomplete multi-view clustering (IMVC) has garnered increasing attention in recent years due to the common issue of missing data in multi-view datasets. The primary approach to address this challenge involves recovering the missing views before applying conventional multi-view clustering methods. Although imputation-based IMVC methods have achieved significant improvements, they still encounter notable limitations: 1) heavy reliance on paired data for training the data recovery module, which is impractical in real scenarios with high missing data rates; 2) the generated data often lacks diversity and discriminability, resulting in suboptimal clustering results. To address these shortcomings, we propose a novel IMVC method called Diffusion Contrastive Generation (DCG). Motivated by the consistency between the diffusion and clustering processes, DCG learns the distribution characteristics to enhance clustering by applying forward diffusion and reverse denoising processes to intra-view data. By performing contrastive learning on a limited set of paired multi-view samples, DCG can align the generated views with the real views, facilitating accurate recovery of views across arbitrary missing view scenarios. Additionally, DCG integrates instance-level and category-level interactive learning to exploit the consistent and complementary information available in multi-view data, achieving robust and end-to-end clustering. Extensive experiments demonstrate that our method outperforms state-of-the-art approaches. The code is available at https://github.com/zhangyuanyang21/2025-AAAI-DCG.

Chenbin Zhang, Zhiqiang Hu, Chuchu Jiang et al.

Drug-target binding affinity prediction is a fundamental task for drug discovery. It has been extensively explored in literature and promising results are reported. However, in this paper, we demonstrate that the results may be misleading and cannot be well generalized to real practice. The core observation is that the canonical randomized split of a test set in conventional evaluation leaves the test set dominated by samples with high similarity to the training set. The performance of models is severely degraded on samples with lower similarity to the training set but the drawback is highly overlooked in current evaluation. As a result, the performance can hardly be trusted when the model meets low-similarity samples in real practice. To address this problem, we propose a framework of similarity aware evaluation in which a novel split methodology is proposed to adapt to any desired distribution. This is achieved by a formulation of optimization problems which are approximately and efficiently solved by gradient descent. We perform extensive experiments across five representative methods in four datasets for two typical target evaluations and compare them with various counterpart methods. Results demonstrate that the proposed split methodology can significantly better fit desired distributions and guide the development of models. Code is released at https://github.com/Amshoreline/SAE/tree/main.