Xiaohang Nie

Xiaohang Nie, Zihan Guo, Kezhuo Yang et al.

AI agents are rapidly expanding in both capability and population: they now write code, operate computers across platforms, manage cloud infrastructure, and make purchasing decisions, while open-source frameworks such as OpenClaw are putting personal agents in the hands of millions and embodied agents are spreading across smartphones, vehicles, and robots. As the internet prepares to host billions of such entities, it is shifting toward what we call Open Agentic Web, a decentralized digital ecosystem in which agents from different users, organizations, and runtimes can discover one another, negotiate task boundaries, and delegate work across open technical and social surfaces at scale. Yet most of today's agents remain isolated tools or closed-ecosystem orchestrators rather than socially integrated participants in open networks. We argue that the next generation of agents must become Agentic Citizens, defined by three requirements: Agentic-Web-Native Collaboration, participation in open collaboration networks rather than only closed internal orchestration; Agent Identity and Personhood, continuity as a social entity rather than a resettable function call; and Lifelong Evolution, improvement across task performance, communication, and collaboration over time. We present Synergy, a general-purpose agent architecture and runtime harness for persistent, collaborative, and evolving agents on Open Agentic Web, grounding collaboration in session-native orchestration, repository-backed workspaces, and social communication; identity in typed memory, notes, agenda, skills, and persistent social relationships; and evolution in an experience-centered learning mechanism that proactively recalls rewarded trajectories at inference time.

Xiaohang Nie, Zihan Guo, Zicai Cui et al.

As large language models (LLM)-driven agents transition from isolated task solvers to persistent digital entities, the emergence of the Agentic Web, an ecosystem where heterogeneous agents autonomously interact and co-evolve, marks a pivotal shift toward Artificial General Intelligence (AGI). However, LLM-based multi-agent systems (LaMAS) are hindered by open-world issues such as scaling friction, coordination breakdown, and value dissipation. To address these challenges, we introduce Holos, a web-scale LaMAS architected for long-term ecological persistence. Holos adopts a five-layer architecture, with core modules primarily featuring the Nuwa engine for high-efficiency agent generation and hosting, a market-driven Orchestrator for resilient coordination, and an endogenous value cycle to achieve incentive compatibility. By bridging the gap between micro-level collaboration and macro-scale emergence, Holos hopes to lay the foundation for the next generation of the self-organizing and continuously evolving Agentic Web. We have publicly released Holos (accessible at https://holosai.io), providing a resource for the community and a testbed for future research in large-scale agentic ecosystems.

Zihan Guo, Zhiyu Chen, Xiaohang Nie et al.

With the rapid evolution of Large Language Model (LLM) agent ecosystems, centralized skill marketplaces have emerged as pivotal infrastructure for augmenting agent capabilities. However, these marketplaces face unprecedented security challenges, primarily stemming from semantic-behavioral inconsistency and inter-skill combinatorial risks, where individually benign skills induce malicious behaviors during collaborative invocation. To address these vulnerabilities, we propose SkillProbe, a multi-stage security auditing framework driven by multi-agent collaboration. SkillProbe introduces a "Skills-for-Skills" design paradigm, encapsulating auditing processes into standardized skill modules to drive specialized agents through a rigorous pipeline, including admission filtering, semantic-behavioral alignment detection, and combinatorial risk simulation. We conducted a large-scale evaluation using 8 mainstream LLM series across 2,500 real-world skills from ClawHub. Our results reveal a striking popularity-security paradox, where download volume is not a reliable proxy for security quality, as over 90% of high-popularity skills failed to pass rigorous auditing. Crucially, we discovered that high-risk skills form a single giant connected component within the risk-link dimension, demonstrating that cascaded risks are systemic rather than isolated occurrences. We hope that SkillProbe will inspire researchers to provide a scalable governance infrastructure for constructing a trustworthy Agentic Web. SkillProbe is accessible for public experience at skillhub.holosai.io.

Zhichong Zheng, Xiaohang Nie, Xueqi Wang et al.

Forecasting evolving clinical risks relies on intrinsic pathological dependencies rather than mere chronological proximity, yet current methods struggle with coarse binary supervision and physical timestamps. To align predictive modeling with clinical logic, we propose the Medical-semantics Aware Time-ALiBi Transformer (MATA-Former), utilizing event semantics to dynamically parameterize attention weights to prioritize causal validity over time lags. Furthermore, we introduce Plateau-Gaussian Soft Labeling (PSL), reformulating binary classification into continuous multi-horizon regression for full-trajectory risk modeling. Evaluated on SIICU -- a newly constructed dataset featuring over 506k events with rigorous expert-verified, fine-grained annotations -- and the MIMIC-IV dataset, our framework demonstrates superior efficacy and robust generalization in capturing risks from text-intensive, irregular clinical time series.