Zongru Shao

Yichao Liu, Zongru Shao, Yueyang Teng et al.

Cross-dose denoising for low-dose positron emission tomography (LDPET) has been proposed to address the limited generalization of models trained at a single noise level. In practice, neural networks trained on a specific dose level often fail to generalize to other dose conditions due to variations in noise magnitude and statistical properties. Conventional "one-size-for-all" models attempt to handle this variability but tend to learn averaged representations across noise levels, resulting in degraded performance. In this work, we analyze this limitation and show that standard training formulations implicitly optimize an expectation over heterogeneous noise distributions. To this end, we propose a unified residual noise learning framework that estimates noise directly from low-dose PET images rather than predicting full-dose images. Experiments on large-scale multi-dose PET datasets from two medical centers demonstrate that the proposed method outperforms the "one-size-for-all" model, individual dose-specific U-Net models, and dose-conditioned approaches, achieving improved denoising performance. These results indicate that residual noise learning effectively mitigates the averaging effect and enhances generalization for cross-dose PET denoising.

Yichao Liu, Zongru Shao, Yueyang Teng et al.

Recognizing less salient features is the key for model compression. However, it has not been investigated in the revolutionary attention mechanisms. In this work, we propose a novel normalization-based attention module (NAM), which suppresses less salient weights. It applies a weight sparsity penalty to the attention modules, thus, making them more computational efficient while retaining similar performance. A comparison with three other attention mechanisms on both Resnet and Mobilenet indicates that our method results in higher accuracy. Code for this paper can be publicly accessed at https://github.com/Christian-lyc/NAM.

Zongru Shao, Xin Wang, Zhanyang Liu et al.

Recent research leverages large language models (LLMs) for early mental health detection, such as depression, often optimized with machine-generated data. However, their detection may be subject to unknown weaknesses. Meanwhile, quality control has not been applied to these generated corpora besides limited human verifications. Our goal is to systematically evaluate LLM reasoning and reveal potential weaknesses. To this end, we first provide a systematic evaluation of the reasoning over machine-generated detection and interpretation. Then we use the models' reasoning abilities to explore mitigation strategies for enhanced performance. Specifically, we do the following: A. Design an LLM instruction strategy that allows for systematic analysis of the detection by breaking down the task into several subtasks. B. Design contrastive few-shot and chain-of-thought prompts by selecting typical positive and negative examples of detection reasoning. C. Perform human annotation for the subtasks identified in the first step and evaluate the performance. D. Identify human-preferred detection with desired logical reasoning from the few-shot generation and use them to explore different optimization strategies. We conducted extensive comparisons on the DepTweet dataset across the following subtasks: 1. identifying whether the speaker is describing their own depression; 2. accurately detecting the presence of PHQ-9 symptoms, and 3. finally, detecting depression. Human verification of statistical outliers shows that LLMs demonstrate greater accuracy in analyzing and detecting explicit language of depression as opposed to implicit expressions of depression. Two optimization methods are used for performance enhancement and reduction of the statistic bias: supervised fine-tuning (SFT) and direct preference optimization (DPO). Notably, the DPO approach achieves significant performance improvement.

Yichao Liu, Zongru Shao, Nico Hoffmann

A variety of attention mechanisms have been studied to improve the performance of various computer vision tasks. However, the prior methods overlooked the significance of retaining the information on both channel and spatial aspects to enhance the cross-dimension interactions. Therefore, we propose a global attention mechanism that boosts the performance of deep neural networks by reducing information reduction and magnifying the global interactive representations. We introduce 3D-permutation with multilayer-perceptron for channel attention alongside a convolutional spatial attention submodule. The evaluation of the proposed mechanism for the image classification task on CIFAR-100 and ImageNet-1K indicates that our method stably outperforms several recent attention mechanisms with both ResNet and lightweight MobileNet.