Guillaume Dardenne

Ambre Marie, Thomas Bertin, Guillaume Dardenne et al.

Automatic speech recognition for French medical conversations remains challenging, with word error rates often exceeding 30% in spontaneous clinical speech. This study proposes a multi-pass LLM post-processing architecture alternating between Speaker Recognition and Word Recognition passes to improve transcription accuracy and speaker attribution. Ablation studies on two French clinical datasets (suicide prevention telephone counseling and preoperative awake neurosurgery consultations) investigate four design choices: model selection, prompting strategy, pass ordering, and iteration depth. Using Qwen3-Next-80B, Wilcoxon signed-rank tests confirm significant WDER reductions on suicide prevention conversations (p<0.05, n=18), while maintaining stability on awake neurosurgery consultations (n=10), with zero output failures and acceptable computational cost (RTF 0.32), suggesting feasibility for offline clinical deployment, pending validation on larger corpora.

Aziliz Guezou-Philippe, Arnaud Clavé, Ehouarn Maguet et al.

Background. Osteoarthritis affects about 528 million people worldwide, causing pain and stiffness in the joints. Arthroplasty is commonly performed to treat joint osteoarthritis, reducing pain and improving mobility. Nevertheless, a significant share of patients remain unsatisfied with their surgery. Personalised arthroplasty was introduced to improve surgical outcomes however current solutions require delays, making it difficult to integrate in clinical routine. We propose a fully automated workflow to design patient-specific implants for total knee arthroplasty. Methods. The proposed pipeline first uses artificial neural networks to segment the femur and tibia proximal and distal extremities. Then the full bones are reconstructed using augmented statistical shape models, combining shape and landmarks information. Finally, 77 morphological parameters are computed to design patient-specific implants. The developed workflow has been trained on 91 CT scans and evaluated on 41 CT scans, in terms of accuracy and execution time. Results. The workflow accuracy was $0.4\pm0.2mm$ for segmentation, $1.0\pm0.3mm$ for full bone reconstruction, and $2.2\pm1.5mm$ for anatomical landmarks determination. The custom implants fitted the patients' anatomy with $0.9\pm0.5mm$ accuracy. The whole process from segmentation to implants' design lasted about 15 minutes. Conclusion. The proposed workflow performs a fast and reliable personalisation of knee implants, directly from a CT image without requiring any manual intervention. It allows the establishment of a patient-specific pre-operative planning in a very short time, making it easily available for all patients. Combined with efficient implant manufacturing techniques, this solution could help answer the growing number of arthroplasties while reducing complications and improving patients' satisfaction.

Ambre Marie, Marine Garnier, Thomas Bertin et al.

Suicide remains a public health challenge, necessitating improved detection methods to facilitate timely intervention and treatment. This systematic review evaluates the role of Artificial Intelligence (AI) and Machine Learning (ML) in assessing suicide risk through acoustic analysis of speech. Following PRISMA guidelines, we analyzed 33 articles selected from PubMed, Cochrane, Scopus, and Web of Science databases. The last search was conducted in February 2025. Risk of bias was assessed using the PROBAST tool. Studies analyzing acoustic features between individuals at risk of suicide (RS) and those not at risk (NRS) were included, while studies lacking acoustic data, a suicide-related focus, or sufficient methodological details were excluded. Sample sizes varied widely and were reported in terms of participants or speech segments, depending on the study. Results were synthesized narratively based on acoustic features and classifier performance. Findings consistently showed significant acoustic feature variations between RS and NRS populations, particularly involving jitter, fundamental frequency (F0), Mel-frequency cepstral coefficients (MFCC), and power spectral density (PSD). Classifier performance varied based on algorithms, modalities, and speech elicitation methods, with multimodal approaches integrating acoustic, linguistic, and metadata features demonstrating superior performance. Among the 29 classifier-based studies, reported AUC values ranged from 0.62 to 0.985 and accuracies from 60% to 99.85%. Most datasets were imbalanced in favor of NRS, and performance metrics were rarely reported separately by group, limiting clear identification of direction of effect.

Ambre Marie, Ilias Maoudj, Guillaume Dardenne et al.

The 1st SpeechWellness Challenge conveys the need for speech-based suicide risk assessment in adolescents. This study investigates a multimodal approach for this challenge, integrating automatic transcription with WhisperX, linguistic embeddings from Chinese RoBERTa, and audio embeddings from WavLM. Additionally, handcrafted acoustic features -- including MFCCs, spectral contrast, and pitch-related statistics -- were incorporated. We explored three fusion strategies: early concatenation, modality-specific processing, and weighted attention with mixup regularization. Results show that weighted attention provided the best generalization, achieving 69% accuracy on the development set, though a performance gap between development and test sets highlights generalization challenges. Our findings, strictly tied to the MINI-KID framework, emphasize the importance of refining embedding representations and fusion mechanisms to enhance classification reliability.

Vincent Jaouen, Pierre-Henri Conze, Guillaume Dardenne et al.

In image registration, many efforts have been devoted to the development of alternatives to the popular normalized mutual information criterion. Concurrently to these efforts, an increasing number of works have demonstrated that substantial gains in registration accuracy can also be achieved by aligning structural representations of images rather than images themselves. Following this research path, we propose a new method for mono- and multimodal image registration based on the alignment of regularized vector fields derived from structural information such as gradient vector flow fields, a technique we call \textit{vector field similarity}. Our approach can be combined in a straightforward fashion with any existing registration framework by substituting vector field similarity to intensity-based registration. In our experiments, we show that the proposed approach compares favourably with conventional image alignment on several public image datasets using a diversity of imaging modalities and anatomical locations.

Alireza Asvadi, Guillaume Dardenne, Jocelyne Troccaz et al.

In this study, we investigated a method allowing the determination of the femur bone surface as well as its mechanical axis from some easy-to-identify bony landmarks. The reconstruction of the whole femur is therefore performed from these landmarks using a Statistical Shape Model (SSM). The aim of this research is therefore to assess the impact of the number, the position, and the accuracy of the landmarks for the reconstruction of the femur and the determination of its related mechanical axis, an important clinical parameter to consider for the lower limb analysis. Two statistical femur models were created from our in-house dataset and a publicly available dataset. Both were evaluated in terms of average point-to-point surface distance error and through the mechanical axis of the femur. Furthermore, the clinical impact of using landmarks on the skin in replacement of bony landmarks is investigated. The predicted proximal femurs from bony landmarks were more accurate compared to on-skin landmarks while both had less than 3.5 degrees mechanical axis angle deviation error. The results regarding the non-invasive determination of the mechanical axis are very encouraging and could open very interesting clinical perspectives for the analysis of the lower limb either for orthopedics or functional rehabilitation.