Sunwoo Kwak

Fengbei Liu, Rachit Saluja, Sunwoo Kwak et al.

Multi-objective optimization (MOO) underlies many machine learning problems, yet MOO solvers across the loss-balancing, gradient-balancing, and Pareto-based families almost universally hand their reconciled directions to Adam~\cite{kingma2015adam}. We show this coupling introduces two systematic gaps between the solver's intent and the optimizer's execution. The first is a \emph{weighting mismatch}: Adam's second-moment denominator entangles the time-varying preference vector with gradient statistics, marginalizing the preference into a history average and collapsing distinct Pareto trade-offs toward a near-uniform mixture. The second is a \emph{geometric mismatch}: Adam's adaptive metric distorts the Euclidean geometry MOO solvers assume, turning aligned objectives into apparent conflicts. To resolve both jointly, we introduce \textbf{MAdam} (Metric-Aware Multi-Objective Adam), a drop-in wrapper that leaves both solver and optimizer unchanged. MAdam preconditions the reconciled direction by the preference-conditioned curvature of the scalarized objective; on this whitened input, Adam's second moment collapses to identity, so the realized update is governed by the preference-conditioned metric. Across multi-task learning, Pareto-front recovery, physics-informed neural networks, and medical imaging, MAdam consistently improves over Adam for every solver family.

Hexin Dong, Yi Lin, Pengyu Zhou et al.

Chest X-ray (CXR) interpretation is hindered by the long-tailed distribution of pathologies and the open-world nature of clinical environments. Existing benchmarks often rely on closed-set classes from a single institution, failing to capture the prevalence of rare diseases or the appearance of novel findings. To address this, we present the CXR-LT challenge. The first event, CXR-LT 2023, established a large-scale benchmark for long-tailed multi-label CXR classification and identified key challenges in rare disease recognition. CXR-LT 2024 further expanded the label space and introduced a zero-shot task to study generalization to unseen findings. Building on the success of CXR-LT 2023 and 2024, this third iteration of the benchmark introduces a multi-center dataset comprising over 145,000 images from PadChest and NIH Chest X-ray datasets. Additionally, all development and test sets in CXR-LT 2026 are annotated by radiologists, providing a more reliable and clinically grounded evaluation than report-derived labels. The challenge defines two core tasks this year: (1) Robust Multi-Label Classification on 30 known classes and (2) Open-World Generalization to 6 unseen (out-of-distribution) rare disease classes. This paper summarizes the overview of the CXR-LT 2026 challenge. We describe the data collection and annotation procedures, analyze solution strategies adopted by participating teams, and evaluate head-versus-tail performance, calibration, and cross-center generalization gaps. Our results show that vision-language foundation models improve both in-distribution and zero-shot performance, but detecting rare findings under multi-center shift remains challenging. Our study provides a foundation for developing and evaluating AI systems in realistic long-tailed and open-world clinical conditions.

Fengbei Liu, Sunwoo Kwak, Hao Phung et al.

Non-contrast chest CTs offer a rich opportunity for both conventional pulmonary and opportunistic extra-pulmonary screening. While Multi-Task Learning (MTL) can unify these diverse tasks, standard hard-parameter sharing approaches are often suboptimal for modeling distinct pathologies. We propose HyperCT, a framework that dynamically adapts a Vision Transformer backbone via a Hypernetwork. To ensure computational efficiency, we integrate Low-Rank Adaptation (LoRA), allowing the model to regress task-specific low-rank weight updates rather than full parameters. Validated on a large-scale dataset of radiological and cardiological tasks, \method{} outperforms various strong baselines, offering a unified, parameter-efficient solution for holistic patient assessment. Our code is available at https://github.com/lfb-1/HyperCT.