Lorenzo Federici

Alessandro Zavoli, Lorenzo Federici

This paper investigates the use of Reinforcement Learning for the robust design of low-thrust interplanetary trajectories in presence of severe disturbances, modeled alternatively as Gaussian additive process noise, observation noise, control actuation errors on thrust magnitude and direction, and possibly multiple missed thrust events. The optimal control problem is recast as a time-discrete Markov Decision Process to comply with the standard formulation of reinforcement learning. An open-source implementation of the state-of-the-art algorithm Proximal Policy Optimization is adopted to carry out the training process of a deep neural network, used to map the spacecraft (observed) states to the optimal control policy. The resulting Guidance and Control Network provides both a robust nominal trajectory and the associated closed-loop guidance law. Numerical results are presented for a typical Earth-Mars mission. First, in order to validate the proposed approach, the solution found in a (deterministic) unperturbed scenario is compared with the optimal one provided by an indirect technique. Then, the robustness and optimality of the obtained closed-loop guidance laws is assessed by means of Monte Carlo campaigns performed in the considered uncertain scenarios. These preliminary results open up new horizons for the use of reinforcement learning in the robust design of interplanetary missions.

Edoardo Conti, Riccardo Rosati, Lorenzo Federici et al.

Purpose: This study provides the first comprehensive evaluation of foundation models in fetal ultrasound (US) imaging under low inter-class variability conditions. While recent vision foundation models such as DINOv3 have shown remarkable transferability across medical domains, their ability to discriminate anatomically similar structures has not been systematically investigated. We address this gap by focusing on fetal brain standard planes--transthalamic (TT), transventricular (TV), and transcerebellar (TC)--which exhibit highly overlapping anatomical features and pose a critical challenge for reliable biometric assessment. Methods: To ensure a fair and reproducible evaluation, all publicly available fetal ultrasound datasets were curated and aggregated into a unified multicenter benchmark, FetalUS-188K, comprising more than 188,000 annotated images from heterogeneous acquisition settings. DINOv3 was pretrained in a self-supervised manner to learn ultrasound-aware representations. The learned features were then evaluated through standardized adaptation protocols, including linear probing with frozen backbone and full fine-tuning, under two initialization schemes: (i) pretraining on FetalUS-188K and (ii) initialization from natural-image DINOv3 weights. Results: Models pretrained on fetal ultrasound data consistently outperformed those initialized on natural images, with weighted F1-score improvements of up to 20 percent. Domain-adaptive pretraining enabled the network to preserve subtle echogenic and structural cues crucial for distinguishing intermediate planes such as TV. Conclusion: Results demonstrate that generic foundation models fail to generalize under low inter-class variability, whereas domain-specific pretraining is essential to achieve robust and clinically reliable representations in fetal brain ultrasound imaging.

Lorenzo Federici, Boris Benedikter, Alessandro Zavoli

This paper presents the main characteristics of the evolutionary optimization code named EOS, Evolutionary Optimization at Sapienza, and its successful application to challenging, real-world space trajectory optimization problems. EOS is a global optimization algorithm for constrained and unconstrained problems of real-valued variables. It implements a number of improvements to the well-known Differential Evolution (DE) algorithm, namely, a self-adaptation of the control parameters, an epidemic mechanism, a clustering technique, an $\varepsilon$-constrained method to deal with nonlinear constraints, and a synchronous island-model to handle multiple populations in parallel. The results reported prove that EOSis capable of achieving increased performance compared to state-of-the-art single-population self-adaptive DE algorithms when applied to high-dimensional or highly-constrained space trajectory optimization problems.

Lorenzo Federici, Alessandro Zavoli, Guido Colasurdo et al.

This paper presents a methodology for the concurrent first-stage preliminary design and ascent trajectory optimization, with application to a Vega-derived Light Launch Vehicle. The reuse as first stage of an existing upper-stage (Zefiro 40) requires a propellant grain geometry redesign, in order to account for the mutated operating conditions. An optimization code based on the parallel running of several Differential Evolution algorithms is used to find the optimal internal pressure law during Z40 operation, together with the optimal thrust direction and other relevant flight parameters of the entire ascent trajectory. Payload injected into a target orbit is maximized, while respecting multiple design constraints, either involving the alone solid rocket motor or dependent on the actual flight trajectory. Numerical results for SSO injection are presented.

Lorenzo Federici, Alessandro Zavoli, Guido Colasurdo

This paper proposes a formulation of the Active Debris Removal (ADR) Mission Design problem as a modified Time-Dependent Traveling Salesman Problem (TDTSP). The TDTSP is a well-known combinatorial optimization problem, whose solution is the cheapest mono-cyclic tour connecting a number of non-stationary cities in a map. The problem is tackled with an optimization procedure based on Simulated Annealing, that efficiently exploits a natural encoding and a careful choice of mutation operators. The developed algorithm is used to simultaneously optimize the targets sequence and the rendezvous epochs of an impulsive ADR mission. Numerical results are presented for sets comprising up to 20 targets.