Emma Sun

Jordan L. Cahoon, Chloe Stanwyck, Asad Aali et al.

Health systems are rapidly deploying large language models (LLMs) that use clinical notes for clinical decision support applications. However, modern documentation practices rely heavily on templates, copy--paste shortcuts, and auto-populated fields, producing extensive duplicated text (``note bloat'') that dilutes clinically meaningful signal and substantially increases the computational cost of LLM use. We introduce TRACE, a scalable preprocessing pipeline that removes note bloat by leveraging EHR attribution metadata to identify templated and copied content and applying frequency-based deduplication when metadata are unavailable. We evaluated TRACE across four real--world clinical cohorts spanning liver transplantation, obstetrics, and inpatient care (5.3 million notes) using blinded physician review and downstream modeling tasks. TRACE removed 47.3% of chart text while preserving performance for information extraction and clinical outcome prediction. At a large academic medical center, this reduction corresponds to an estimated $9.5 million annual decrease in LLM inference costs assuming one query per encounter. These findings show how underutilized EHR metadata can enable more scalable and cost-efficient deployment of LLM-based clinical systems.

Joshua Strong, Pramit Saha, Emma Sun et al.

Learning to Defer (L2D) enables a model to predict autonomously or defer to an expert, but prior work largely assumes flat label spaces. We study the first L2D setting with hierarchical multi-label decisions, motivated by medical-imaging workflows in which findings are organised by clinical taxonomies. In this setting, deferral is a delegation action rather than a label assignment, so treating it as an independent per-label decision can produce deferral incoherence, including taxonomic contradictions, delegation violations, and deferrals of labels already implied by the model's own assertions. We formalise coherent hierarchical deferral under a Selective-Exclusion handoff contract, characterise the Bayes-optimal coherent deferral rule, and show that even nodewise Bayes L2D can be action-incoherent. We then propose two remedies: exact coherent projection, a dynamic-programming decoder over the coherent action set, and Taxonomic Belief Propagation (TBP) with Recursive Policy Optimisation (RPO), a contract-aware joint action model trained through the same recursion used at inference. Across real-reader and controlled-expert medical-imaging benchmarks, naive binary-relevance L2D exhibits non-trivial incoherence. Projection removes it exactly, and fast TBP+RPO drives incoherence near zero while retaining strong utility.