Siyuan Chen

Siyuan Chen, Zhuofeng Wang, Zelong Guan et al.

Fine-tuning large language models (LLMs) requires significant memory, often exceeding the capacity of a single GPU. A common solution to this memory challenge is offloading compute and data from the GPU to the CPU. However, this approach is hampered by the limited bandwidth of commodity hardware, which constrains communication between the CPU and GPU, and by slower matrix multiplications on the CPU. In this paper, we present an offloading framework, LSP-Offload, that enables near-native speed LLM fine-tuning on commodity hardware through learned sparse projectors. Our data-driven approach involves learning efficient sparse compressors that minimize communication with minimal precision loss. Additionally, we introduce a novel layer-wise communication schedule to maximize parallelism between communication and computation. As a result, our framework can fine-tune a 1.3 billion parameter model on a 4GB laptop GPU and a 6.7 billion parameter model on a 24GB NVIDIA RTX 4090 GPU. Compared to state-of-the-art offloading frameworks, our approach reduces end-to-end fine-tuning time by 33.1%-62.5% when converging to the same accuracy. We open source our framework at https://github.com/gulang2019/LSP-Offload.

Siyuan Chen, Minghao Guo, Caoliwen Wang et al.

Biomolecular interaction modeling has been substantially advanced by foundation models, yet they often produce all-atom structures that violate basic steric feasibility. We address this limitation by enforcing physical validity as a strict constraint during both training and inference with a uniffed module. At its core is a differentiable projection that maps the provisional atom coordinates from the diffusion model to the nearest physically valid conffguration. This projection is achieved using a Gauss-Seidel scheme, which exploits the locality and sparsity of the constraints to ensure stable and fast convergence at scale. By implicit differentiation to obtain gradients, our module integrates seamlessly into existing frameworks for end-to-end ffnetuning. With our Gauss-Seidel projection module in place, two denoising steps are sufffcient to produce biomolecular complexes that are both physically valid and structurally accurate. Across six benchmarks, our 2-step model achieves the same structural accuracy as state-of-the-art 200-step diffusion baselines, delivering approximately 10 times faster wall-clock speed while guaranteeing physical validity.