Chongyu Wang

Xinyan Wang, Ting Jia, Chongyu Wang et al. · tsinghua

Accurate identification of disease genes has consistently been one of the keys to decoding a disease's molecular mechanism. Most current approaches focus on constructing biological networks and utilizing machine learning, especially, deep learning to identify disease genes, but ignore the complex relations between entities in the biological knowledge graph. In this paper, we construct a biological knowledge graph centered on diseases and genes, and develop an end-to-end Knowledge graph completion model for Disease Gene Prediction using interactional tensor decomposition (called KDGene). KDGene introduces an interaction module between the embeddings of entities and relations to tensor decomposition, which can effectively enhance the information interaction in biological knowledge. Experimental results show that KDGene significantly outperforms state-of-the-art algorithms. Furthermore, the comprehensive biological analysis of the case of diabetes mellitus confirms KDGene's ability for identifying new and accurate candidate genes. This work proposes a scalable knowledge graph completion framework to identify disease candidate genes, from which the results are promising to provide valuable references for further wet experiments.

Yana Wei, Zeen Chi, Chongyu Wang et al.

In open-world environments, human-object interactions (HOIs) evolve continuously, challenging conventional closed-world HOI detection models. Inspired by humans' ability to progressively acquire knowledge, we explore incremental HOI detection (IHOID) to develop agents capable of discerning human-object relations in such dynamic environments. This setup confronts not only the common issue of catastrophic forgetting in incremental learning but also distinct challenges posed by interaction drift and detecting zero-shot HOI combinations with sequentially arriving data. Therefore, we propose a novel exemplar-free incremental relation distillation (IRD) framework. IRD decouples the learning of objects and relations, and introduces two unique distillation losses for learning invariant relation features across different HOI combinations that share the same relation. Extensive experiments on HICO-DET and V-COCO datasets demonstrate the superiority of our method over state-of-the-art baselines in mitigating forgetting, strengthening robustness against interaction drift, and generalization on zero-shot HOIs. Code is available at \href{https://github.com/weiyana/ContinualHOI}{this HTTP URL}

Tao Liu, Chongyu Wang, Rongjie Li et al.

While Multimodal Large Language Models (MLLMs) have advanced GUI navigation agents, current approaches face limitations in cross-domain generalization and effective history utilization. We present a reasoning-enhanced framework that systematically integrates structured reasoning, action prediction, and history summarization. The structured reasoning component generates coherent Chain-of-Thought analyses combining progress estimation and decision reasoning, which inform both immediate action predictions and compact history summaries for future steps. Based on this framework, we train a GUI agent, \textbf{GUI-Rise}, through supervised fine-tuning on pseudo-labeled trajectories and reinforcement learning with Group Relative Policy Optimization (GRPO). This framework employs specialized rewards, including a history-aware objective, directly linking summary quality to subsequent action performance. Comprehensive evaluations on standard benchmarks demonstrate state-of-the-art results under identical training data conditions, with particularly strong performance in out-of-domain scenarios. These findings validate our framework's ability to maintain robust reasoning and generalization across diverse GUI navigation tasks. Code is available at https://leon022.github.io/GUI-Rise.

Zhen Liu, Xinyu Ning, Zhe Hu et al.

Recent vision-language-action (VLA) systems have demonstrated strong capabilities in embodied manipulation. However, most existing VLA policies rely on limited observation windows and end-to-end action prediction, which makes them brittle in long-horizon, memory-dependent tasks with partial observability, occlusions, and multi-stage dependencies. Such tasks require not only precise visuomotor control, but also persistent memory, adaptive task decomposition, and explicit recovery from execution failures. To address these limitations, we propose a dual-system framework for long-horizon embodied manipulation. Our framework explicitly separates high-level semantic reasoning from low-level motor execution. A high-level planner, implemented as a VLM-based agentic module, maintains structured task memory and performs goal decomposition, outcome verification, and error-driven correction. A low-level executor, instantiated as a VLA-based visuomotor controller, carries out each sub-task through diffusion-based action generation conditioned on geometry-preserving filtered observations. Together, the two systems form a closed loop between planning and execution, enabling memory-aware reasoning, adaptive replanning, and robust online recovery. Experiments on representative RMBench tasks show that the proposed framework substantially outperforms representative baselines, achieving a 32.4% average success rate compared with 9.8% for the strongest baseline. Ablation studies further confirm the importance of structured memory and closed-loop recovery for long-horizon manipulation.

Tao Liu, Rongjie Li, Chongyu Wang et al.

Open-vocabulary Scene Graph Generation (OV-SGG) overcomes the limitations of the closed-set assumption by aligning visual relationship representations with open-vocabulary textual representations. This enables the identification of novel visual relationships, making it applicable to real-world scenarios with diverse relationships. However, existing OV-SGG methods are constrained by fixed text representations, limiting diversity and accuracy in image-text alignment. To address these challenges, we propose the Relation-Aware Hierarchical Prompting (RAHP) framework, which enhances text representation by integrating subject-object and region-specific relation information. Our approach utilizes entity clustering to address the complexity of relation triplet categories, enabling the effective integration of subject-object information. Additionally, we utilize a large language model (LLM) to generate detailed region-aware prompts, capturing fine-grained visual interactions and improving alignment between visual and textual modalities. RAHP also introduces a dynamic selection mechanism within Vision-Language Models (VLMs), which adaptively selects relevant text prompts based on the visual content, reducing noise from irrelevant prompts. Extensive experiments on the Visual Genome and Open Images v6 datasets demonstrate that our framework consistently achieves state-of-the-art performance, demonstrating its effectiveness in addressing the challenges of open-vocabulary scene graph generation. The code is available at: https://github.com/Leon022/RAHP

Haodong Wang, Chongyu Wang, Yinghui Quan et al.

Expanding the receptive field in a deep learning model for large-scale 3D point cloud segmentation is an effective technique for capturing rich contextual information, which consequently enhances the network's ability to learn meaningful features. However, this often leads to increased computational complexity and risk of overfitting, challenging the efficiency and effectiveness of the learning paradigm. To address these limitations, we propose the Local Split Attention Pooling (LSAP) mechanism to effectively expand the receptive field through a series of local split operations, thus facilitating the acquisition of broader contextual knowledge. Concurrently, it optimizes the computational workload associated with attention-pooling layers to ensure a more streamlined processing workflow. Based on LSAP, a Parallel Aggregation Enhancement (PAE) module is introduced to enable parallel processing of data using both 2D and 3D neighboring information to further enhance contextual representations within the network. In light of the aforementioned designs, we put forth a novel framework, designated as LSNet, for large-scale point cloud semantic segmentation. Extensive evaluations demonstrated the efficacy of seamlessly integrating the proposed PAE module into existing frameworks, yielding significant improvements in mean intersection over union (mIoU) metrics, with a notable increase of up to 11%. Furthermore, LSNet demonstrated superior performance compared to state-of-the-art semantic segmentation networks on three benchmark datasets, including S3DIS, Toronto3D, and SensatUrban. It is noteworthy that our method achieved a substantial speedup of approximately 38.8% compared to those employing similar-sized receptive fields, which serves to highlight both its computational efficiency and practical utility in real-world large-scale scenes.

Qi Mao, Chongyu Wang, Meng Wang et al.

The accelerated proliferation of visual content and the rapid development of machine vision technologies bring significant challenges in delivering visual data on a gigantic scale, which shall be effectively represented to satisfy both human and machine requirements. In this work, we investigate how hierarchical representations derived from the advanced generative prior facilitate constructing an efficient scalable coding paradigm for human-machine collaborative vision. Our key insight is that by exploiting the StyleGAN prior, we can learn three-layered representations encoding hierarchical semantics, which are elaborately designed into the basic, middle, and enhanced layers, supporting machine intelligence and human visual perception in a progressive fashion. With the aim of achieving efficient compression, we propose the layer-wise scalable entropy transformer to reduce the redundancy between layers. Based on the multi-task scalable rate-distortion objective, the proposed scheme is jointly optimized to achieve optimal machine analysis performance, human perception experience, and compression ratio. We validate the proposed paradigm's feasibility in face image compression. Extensive qualitative and quantitative experimental results demonstrate the superiority of the proposed paradigm over the latest compression standard Versatile Video Coding (VVC) in terms of both machine analysis as well as human perception at extremely low bitrates ($<0.01$ bpp), offering new insights for human-machine collaborative compression.

Chongyu Wang, Ting Huang, Chunyu Sun et al.

Multimodal Large Language Models (MLLMs) have achieved remarkable progress in 2D visual tasks but still exhibit limited physical spatial awareness when processing real-world visual streams. Recently, feed-forward geometric foundation models, which implicitly extract geometric priors, have provided a new pathway to address this issue. However, existing geometry-aware MLLMs are predominantly constrained by the paradigm of single deep-layer extraction and input-level fusion. This flattened fusion leads to the loss of local geometric details and causes semantic mismatches in the early layers. To break this bottleneck, we propose GUIDE (Geometric Unrolling Inside MLLM Early-layers), a progressive geometric priors injection framework. GUIDE performs multi-level sampling within the geometric encoder, comprehensively capturing multi-granularity features ranging from local edges to global topologies. Subsequently, we rigorously align and fuse these multi-level geometric priors step-by-step with the early layers of the MLLM. Building upon the injection of multi-granularity geometric information, this design guides the model to progressively learn the 2D-to-3D transitional process. Furthermore, we introduce a context-aware gating that enables the model to fetch requisite spatial cues based on current semantics, thereby maximizing the utilization efficiency of spatial priors and effectively suppressing redundant geometric noise. Extensive experiments demonstrate that GUIDE significantly outperforms existing baselines on multiple complex spatial reasoning and perception tasks, establishing a novel paradigm for integrating 3D geometric priors into large models.

Jing Liu, Duanchu Wang, Haoran Gong et al.

Understanding and analyzing the spatial semantics and structure of forests is essential for accurate forest resource monitoring and ecosystem research. However, the lack of large-scale and annotated datasets has limited the widespread use of advanced intelligent techniques in this field. To address this challenge, a fully automated synthetic data generation and processing framework based on the concepts of Digital Cousins and Simulation-to-Reality (Sim2Real) is proposed, offering versatility and scalability to any size and platform. Using this process, we created the Boreal3D, the world's largest forest point cloud dataset. It includes 1000 highly realistic and structurally diverse forest plots across four different platforms, totaling 48,403 trees and over 35.3 billion points. Each point is labeled with semantic, instance, and viewpoint information, while each tree is described with structural parameters such as diameter, crown width, leaf area, and total volume. We designed and conducted extensive experiments to evaluate the potential of Boreal3D in advancing fine-grained 3D forest structure analysis in real-world applications. The results demonstrate that with certain strategies, models pre-trained on synthetic data can significantly improve performance when applied to real forest datasets. Especially, the findings reveal that fine-tuning with only 20% of real-world data enables the model to achieve performance comparable to models trained exclusively on entire real-world data, highlighting the value and potential of our proposed framework. The Boreal3D dataset, and more broadly, the synthetic data augmentation framework, is poised to become a critical resource for advancing research in large-scale 3D forest scene understanding and structural parameter estimation.

Chongyu Wang, Kunlei Jing, Jihua Zhu et al.

Open-vocabulary semantic segmentation enables models to recognize and segment objects from arbitrary natural language descriptions, offering the flexibility to handle novel, fine-grained, or functionally defined categories beyond fixed label sets. While this capability is crucial for large-scale urban point clouds that support applications such as digital twins, smart city management, and urban analytics, it remains largely unexplored in this domain. The main obstacles are the frequent absence of high-quality, well-aligned multi-view imagery in large-scale urban point cloud datasets and the poor generalization of existing three-dimensional (3D) segmentation pipelines across diverse urban environments with substantial variation in geometry, scale, and appearance. To address these challenges, we present OpenUrban3D, the first 3D open-vocabulary semantic segmentation framework for large-scale urban scenes that operates without aligned multi-view images, pre-trained point cloud segmentation networks, or manual annotations. Our approach generates robust semantic features directly from raw point clouds through multi-view, multi-granularity rendering, mask-level vision-language feature extraction, and sample-balanced fusion, followed by distillation into a 3D backbone model. This design enables zero-shot segmentation for arbitrary text queries while capturing both semantic richness and geometric priors. Extensive experiments on large-scale urban benchmarks, including SensatUrban and SUM, show that OpenUrban3D achieves significant improvements in both segmentation accuracy and cross-scene generalization over existing methods, demonstrating its potential as a flexible and scalable solution for 3D urban scene understanding.