Brian Chen

Houliang Zhou, Lifang He, Yu Zhang et al.

Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the identification and classification of Alzheimer's disease (AD) using multi-modality brain imaging data. Specifically, we extended the Gradient Class Activation Mapping (Grad-CAM) technique to quantify the most discriminative features identified by GCN from brain connectivity patterns. We then utilized them to find signature regions of interest (ROIs) by detecting the difference of features between regions in healthy control (HC), mild cognitive impairment (MCI), and AD groups. We conducted the experiments on the ADNI database with imaging data from three modalities, including VBM-MRI, FDG-PET, and AV45-PET, and showed that the ROI features learned by our method were effective for enhancing the performances of both clinical score prediction and disease status identification. It also successfully identified biomarkers associated with AD and MCI.

James Stokes, Brian Chen, Shravan Veerapaneni

This article aims to summarize recent and ongoing efforts to simulate continuous-variable quantum systems using flow-based variational quantum Monte Carlo techniques, focusing for pedagogical purposes on the example of bosons in the field amplitude (quadrature) basis. Particular emphasis is placed on the variational real- and imaginary-time evolution problems, carefully reviewing the stochastic estimation of the time-dependent variational principles and their relationship with information geometry. Some practical instructions are provided to guide the implementation of a PyTorch code. The review is intended to be accessible to researchers interested in machine learning and quantum information science.

Andrew Rouditchenko, Angie Boggust, David Harwath et al.

In this paper, we explore self-supervised audio-visual models that learn from instructional videos. Prior work has shown that these models can relate spoken words and sounds to visual content after training on a large-scale dataset of videos, but they were only trained and evaluated on videos in English. To learn multilingual audio-visual representations, we propose a cascaded approach that leverages a model trained on English videos and applies it to audio-visual data in other languages, such as Japanese videos. With our cascaded approach, we show an improvement in retrieval performance of nearly 10x compared to training on the Japanese videos solely. We also apply the model trained on English videos to Japanese and Hindi spoken captions of images, achieving state-of-the-art performance.

Brian Chen, Bo Wu, Alireza Zareian et al.

We formulate a practical yet challenging problem: General Partial Label Learning (GPLL). Compared to the traditional Partial Label Learning (PLL) problem, GPLL relaxes the supervision assumption from instance-level -- a label set partially labels an instance -- to group-level: 1) a label set partially labels a group of instances, where the within-group instance-label link annotations are missing, and 2) cross-group links are allowed -- instances in a group may be partially linked to the label set from another group. Such ambiguous group-level supervision is more practical in real-world scenarios as additional annotation on the instance-level is no longer required, e.g., face-naming in videos where the group consists of faces in a frame, labeled by a name set in the corresponding caption. In this paper, we propose a novel graph convolutional network (GCN) called Dual Bipartite Graph Autoencoder (DB-GAE) to tackle the label ambiguity challenge of GPLL. First, we exploit the cross-group correlations to represent the instance groups as dual bipartite graphs: within-group and cross-group, which reciprocally complements each other to resolve the linking ambiguities. Second, we design a GCN autoencoder to encode and decode them, where the decodings are considered as the refined results. It is worth noting that DB-GAE is self-supervised and transductive, as it only uses the group-level supervision without a separate offline training stage. Extensive experiments on two real-world datasets demonstrate that DB-GAE significantly outperforms the best baseline over absolute 0.159 F1-score and 24.8% accuracy. We further offer analysis on various levels of label ambiguities.