M.M. Ekanayake

Mevan Ekanayake, Zhifeng Chen, Gary Egan et al.

Implicit Neural Representations (INRs) have recently advanced the field of deep learning due to their ability to learn continuous representations of signals without the need for large training datasets. Although INR methods have been studied for medical image super-resolution, their adaptability to localized priors in medical images has not been extensively explored. Medical images contain rich anatomical divisions that could provide valuable local prior information to enhance the accuracy and robustness of INRs. In this work, we propose a novel framework, referred to as the Semantically Conditioned INR (SeCo-INR), that conditions an INR using local priors from a medical image, enabling accurate model fitting and interpolation capabilities to achieve super-resolution. Our framework learns a continuous representation of the semantic segmentation features of a medical image and utilizes it to derive the optimal INR for each semantic region of the image. We tested our framework using several medical imaging modalities and achieved higher quantitative scores and more realistic super-resolution outputs compared to state-of-the-art methods.

E. M. M. B. Ekanayake, H. M. H. K. Weerasooriya, D. Y. L. Ranasinghe et al.

Hyperspectral unmixing (HU) has become an important technique in exploiting hyperspectral data since it decomposes a mixed pixel into a collection of endmembers weighted by fractional abundances. The endmembers of a hyperspectral image (HSI) are more likely to be generated by independent sources and be mixed in a macroscopic degree before arriving at the sensor element of the imaging spectrometer as mixed spectra. Over the past few decades, many attempts have focused on imposing auxiliary constraints on the conventional nonnegative matrix factorization (NMF) framework in order to effectively unmix these mixed spectra. As a promising step toward finding an optimum constraint to extract endmembers, this paper presents a novel blind HU algorithm, referred to as Kurtosis-based Smooth Nonnegative Matrix Factorization (KbSNMF) which incorporates a novel constraint based on the statistical independence of the probability density functions of endmember spectra. Imposing this constraint on the conventional NMF framework promotes the extraction of independent endmembers while further enhancing the parts-based representation of data. Experiments conducted on diverse synthetic HSI datasets (with numerous numbers of endmembers, spectral bands, pixels, and noise levels) and three standard real HSI datasets demonstrate the validity of the proposed KbSNMF algorithm compared to several state-of-the-art NMF-based HU baselines. The proposed algorithm exhibits superior performance especially in terms of extracting endmember spectra from hyperspectral data; therefore, it could uplift the performance of recent deep learning HU methods which utilize the endmember spectra as supervisory input data for abundance extraction.