Rusab Sarmun

Alvee Hassan, Rusab Sarmun, Muhammad E. H. Chowdhury et al.

Early detection of coronary artery disease (CAD) is critical for reducing mortality and improving patient treatment planning. While angiographic image analysis from X-rays is a common and cost-effective method for identifying cardiac abnormalities, including stenotic coronary arteries, poor image quality can significantly impede clinical diagnosis. We present the Coronary Artery Segmentation and Refinement Network (CASR-Net), a three-stage pipeline comprising image preprocessing, segmentation, and refinement. A novel multichannel preprocessing strategy combining CLAHE and an improved Ben Graham method provides incremental gains, increasing Dice Score Coefficient (DSC) by 0.31-0.89% and Intersection over Union (IoU) by 0.40-1.16% compared with using the techniques individually. The core innovation is a segmentation network built on a UNet with a DenseNet121 encoder and a Self-organized Operational Neural Network (Self-ONN) based decoder, which preserves the continuity of narrow and stenotic vessel branches. A final contour refinement module further suppresses false positives. Evaluated with 5-fold cross-validation on a combination of two public datasets that contain both healthy and stenotic arteries, CASR-Net outperformed several state-of-the-art models, achieving an IoU of 61.43%, a DSC of 76.10%, and clDice of 79.36%. These results highlight a robust approach to automated coronary artery segmentation, offering a valuable tool to support clinicians in diagnosis and treatment planning.

Fabiha Bushra, Muhammad E. H. Chowdhury, Rusab Sarmun et al.

The increasing reliance on Computed Tomography Pulmonary Angiography (CTPA) for Pulmonary Embolism (PE) diagnosis presents challenges and a pressing need for improved diagnostic solutions. The primary objective of this study is to leverage deep learning techniques to enhance the Computer Assisted Diagnosis (CAD) of PE. With this aim, we propose a classifier-guided detection approach that effectively leverages the classifier's probabilistic inference to direct the detection predictions, marking a novel contribution in the domain of automated PE diagnosis. Our classification system includes an Attention-Guided Convolutional Neural Network (AG-CNN) that uses local context by employing an attention mechanism. This approach emulates a human expert's attention by looking at both global appearances and local lesion regions before making a decision. The classifier demonstrates robust performance on the FUMPE dataset, achieving an AUROC of 0.927, sensitivity of 0.862, specificity of 0.879, and an F1-score of 0.805 with the Inception-v3 backbone architecture. Moreover, AG-CNN outperforms the baseline DenseNet-121 model, achieving an 8.1% AUROC gain. While previous research has mostly focused on finding PE in the main arteries, our use of cutting-edge object detection models and ensembling techniques greatly improves the accuracy of detecting small embolisms in the peripheral arteries. Finally, our proposed classifier-guided detection approach further refines the detection metrics, contributing new state-of-the-art to the community: mAP$_{50}$, sensitivity, and F1-score of 0.846, 0.901, and 0.779, respectively, outperforming the former benchmark with a significant 3.7% improvement in mAP$_{50}$. Our research aims to elevate PE patient care by integrating AI solutions into clinical workflows, highlighting the potential of human-AI collaboration in medical diagnostics.

Fabi Nahian Madhurja, Rusab Sarmun, Muhammad E. H. Chowdhury et al.

Cervical spine fractures are critical medical conditions requiring precise and efficient detection for effective clinical management. This study explores the viability of 2D projection-based vertebra segmentation for vertebra-level fracture detection in 3D CT volumes, presenting an end-to-end pipeline for automated analysis of cervical vertebrae (C1-C7). By approximating a 3D volume through optimized 2D axial, sagittal, and coronal projections, regions of interest are identified using the YOLOv8 model from all views and combined to approximate the 3D cervical spine area, achieving a 3D mIoU of 94.45 percent. This projection-based localization strategy reduces computational complexity compared to traditional 3D segmentation methods while maintaining high performance. It is followed by a DenseNet121-Unet-based multi-label segmentation leveraging variance- and energy-based projections, achieving a Dice score of 87.86 percent. Strategic approximation of 3D vertebral masks from these 2D segmentation masks enables the extraction of individual vertebra volumes. The volumes are analyzed for fractures using an ensemble of 2.5D Spatio-Sequential models incorporating both raw slices and projections per vertebra for complementary evaluation. This ensemble achieves vertebra-level and patient-level F1 scores of 68.15 and 82.26, and ROC-AUC scores of 91.62 and 83.04, respectively. We further validate our approach through an explainability study that provides saliency map visualizations highlighting anatomical regions relevant for diagnosis, and an interobserver variability analysis comparing our model's performance with expert radiologists, demonstrating competitive results.

Ashiqur Rahman, Muhammad E. H. Chowdhury, Md Sharjis Ibne Wadud et al.

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing ischemic stroke, yet existing segmentation techniques often fail to accurately delineate lesions. This study introduces a novel deep learning-based method for segmenting ischemic stroke lesions using multi-channel MRI modalities, including Diffusion Weighted Imaging (DWI), Apparent Diffusion Coefficient (ADC), and enhanced Diffusion Weighted Imaging (eDWI). The proposed architecture integrates DenseNet121 as the encoder with Self-Organized Operational Neural Networks (SelfONN) in the decoder, enhanced by Channel and Space Compound Attention (CSCA) and Double Squeeze-and-Excitation (DSE) blocks. Additionally, a custom loss function combining Dice Loss and Jaccard Loss with weighted averages is introduced to improve model performance. Trained and evaluated on the ISLES 2022 dataset, the model achieved Dice Similarity Coefficients (DSC) of 83.88% using DWI alone, 85.86% with DWI and ADC, and 87.49% with the integration of DWI, ADC, and eDWI. This approach not only outperforms existing methods but also addresses key limitations in current segmentation practices. These advancements significantly enhance diagnostic precision and treatment planning for ischemic stroke, providing valuable support for clinical decision-making.

Promit Basak, Rusab Sarmun, Saidul Kabir et al.

Automated lumbar spine segmentation is very crucial for modern diagnosis systems. In this study, we introduce a novel machine-agnostic approach for segmenting lumbar vertebrae and intervertebral discs from MRI images, employing a cascaded model that synergizes an ROI detection and a Self-organized Operational Neural Network (Self-ONN)-based encoder-decoder network for segmentation. Addressing the challenge of diverse MRI modalities, our methodology capitalizes on a unique dataset comprising images from 12 scanners and 34 subjects, enhanced through strategic preprocessing and data augmentation techniques. The YOLOv8 medium model excels in ROI extraction, achieving an excellent performance of 0.916 mAP score. Significantly, our Self-ONN-based model, combined with a DenseNet121 encoder, demonstrates excellent performance in lumbar vertebrae and IVD segmentation with a mean Intersection over Union (IoU) of 83.66%, a sensitivity of 91.44%, and Dice Similarity Coefficient (DSC) of 91.03%, as validated through rigorous 10-fold cross-validation. This study not only showcases an effective approach to MRI segmentation in spine-related disorders but also sets the stage for future advancements in automated diagnostic tools, emphasizing the need for further dataset expansion and model refinement for broader clinical applicability.

Md. Sohanur Rahman, Muhammad E. H. Chowdhury, Hasib Ryan Rahman et al.

In this study, we propose a novel and robust framework, Self-DenseMobileNet, designed to enhance the classification of nodules and non-nodules in chest radiographs (CXRs). Our approach integrates advanced image standardization and enhancement techniques to optimize the input quality, thereby improving classification accuracy. To enhance predictive accuracy and leverage the strengths of multiple models, the prediction probabilities from Self-DenseMobileNet were transformed into tabular data and used to train eight classical machine learning (ML) models; the top three performers were then combined via a stacking algorithm, creating a robust meta-classifier that integrates their collective insights for superior classification performance. To enhance the interpretability of our results, we employed class activation mapping (CAM) to visualize the decision-making process of the best-performing model. Our proposed framework demonstrated remarkable performance on internal validation data, achieving an accuracy of 99.28\% using a Meta-Random Forest Classifier. When tested on an external dataset, the framework maintained strong generalizability with an accuracy of 89.40\%. These results highlight a significant improvement in the classification of CXRs with lung nodules.

Saniah Kayenat Chowdhury, Rusab Sarmun, Muhammad E. H. Chowdhury et al.

Accurate lung cancer tumor staging is crucial for prognosis and treatment planning. However, it remains challenging for end-to-end deep learning approaches, as such approaches often overlook spatial and anatomical information that are central to the tumor-node-metastasis system. The tumor stage depends on multiple quantitative criteria, including the tumor size and its proximity to the nearest anatomical structures, and small variations can alter the staging outcome. We propose a medically grounded hybrid pipeline that performs staging by explicitly measuring the tumor's size and distance properties rather than treating it as a pure image classification task. Our method employs specialized encoder-decoder networks to precisely segment the lung and adjacent anatomy, including the lobes, tumor, mediastinum, and diaphragm. Subsequently, we extract the necessary tumor properties, i.e. measure the largest tumor dimension and calculate the distance between the tumor and neighboring anatomical structures by a quantitative analysis of the segmentation masks. Finally, we apply rule-based tumor staging aligned with the medical guidelines. This novel framework has been evaluated on the Lung-PET-CT-Dx dataset, demonstrating superior performance compared to traditional deep learning models, achieving an overall classification accuracy of 91.36%. We report the per-stage F1-scores of 0.93 (T1), 0.89 (T2), 0.96 (T3), and 0.90 (T4), a critical evaluation aspect often omitted in prior literature. To our knowledge, this is the first study that embeds explicit clinical context into tumor stage classification. Unlike standard convolutional neural networks that operate in an uninterpretable "black box" manner, our method offers both state-of-the-art performance and transparent decision support.

Nowshin Sharmily, Rusab Sarmun, Muhammad E. H. Chowdhury et al.

Illegal landfills are posing as a hazardous threat to people all over the world. Due to the arduous nature of manually identifying the location of landfill, many landfills go unnoticed by authorities and later cause dangerous harm to people and environment. Deep learning can play a significant role in identifying these landfills while saving valuable time, manpower and resources. Despite being a burning concern, good quality publicly released datasets for illegal landfill detection are hard to find due to security concerns. However, AerialWaste Dataset is a large collection of 10434 images of Lombardy region of Italy. The images are of varying qualities, collected from three different sources: AGEA Orthophotos, WorldView-3, and Google Earth. The dataset contains professionally curated, diverse and high-quality images which makes it particularly suitable for scalable and impactful research. As we trained several models to compare results, we found complex and heavy models to be prone to overfitting and memorizing training data instead of learning patterns. Therefore, we chose lightweight simpler models which could leverage general features from the dataset. In this study, Mobilenetv2, Googlenet, Densenet, MobileVit and other lightweight deep learning models were used to train and validate the dataset as they achieved significant success with less overfitting. As we saw substantial improvement in the performance using some of these models, we combined the best performing models and came up with an ensemble model. With the help of ensemble and fusion technique, binary classification could be performed on this dataset with 92.33% accuracy, 92.67% precision, 92.33% sensitivity, 92.41% F1 score and 92.71% specificity.